초록 ▼

결과: Anyplex MTB/NTM Real-time Detection kit과 AdvanSure TB/NTM real-time PCR kit간의 검사결과 일치율은 95% (103/108)였으며, 객담검체에 대해서는 96% (77/80), 균주검체에 대해서는 93% (26/28)였다. 활동성 결핵 환자에 대한 민감도 및 양성예측도가 Anyplex MTB/NTM Real-time Detection kit과 AdvanSure TB/NTM real-time PCR kit에서 각각 76%, 84%와 78%, 85%였고, 활동성 비결핵성항산

결과: Anyplex MTB/NTM Real-time Detection kit과 AdvanSure TB/NTM real-time PCR kit간의 검사결과 일치율은 95% (103/108)였으며, 객담검체에 대해서는 96% (77/80), 균주검체에 대해서는 93% (26/28)였다. 활동성 결핵 환자에 대한 민감도 및 양성예측도가 Anyplex MTB/NTM Real-time Detection kit과 AdvanSure TB/NTM real-time PCR kit에서 각각 76%, 84%와 78%, 85%였고, 활동성 비결핵성항산균 환자에 대한 민감도 및 양성예측도는 각각 83%, 100%와 83%, 83%였다. 두 kit 모두 객담도말음성 검체보다 객담도말양성 검체에서 활동성 결핵에 대한 민감도와 양성예측도가 더 높게 나타났으며, Anyplex MTB/NTM Real-time Detection kit는 민감도 1.8배, 양성예측도 1.4배, AdvanSure TB/NTM real-time PCR kit는 민감도 1.7배, 양성예측도 1.4배 더 높은 수치를 보였다.

(출처:요약)

Abstract ▼

Result: The concordance rate between the results of the Anyplex MTB/NTM Real-time Detection kit and the AdvanSure TB/NTM real-time PCR kit was 95% (103/108) for all specimens, 96% (77/80) for sputum specimens, and 93 % (26/28) for strain specimens. For active tuberculosis patients, the sensitivity a

Result: The concordance rate between the results of the Anyplex MTB/NTM Real-time Detection kit and the AdvanSure TB/NTM real-time PCR kit was 95% (103/108) for all specimens, 96% (77/80) for sputum specimens, and 93 % (26/28) for strain specimens. For active tuberculosis patients, the sensitivity and the positive predictive value were 76% and 84% by the Anyplex MTB/NTM Real-time Detection kit, and 78% and 85% by the AdvanSure TB/NTM real-time PCR kit. For active nontuberculous mycobacteria patients, the sensitivity and the positive predictive value were 83% and 100% by the Anyplex MTB/NTM Real-time Detection kit, and 83% and 83% by the AdvanSure TB/NTM real-time PCR kit. Both kits showed higher sensitivity and positive predictive value for active tuberculosis in sputum-positive specimens than sputum-negative specimens. The sensitivity and the positive predictive value of the Anyplex MTB/NTM Real-time Detection kit were, respectively, 1.8 times and 1.4 times higher in sputum-positive specimens than in sputum-negative specimens, and the sensitivity and the positive predictive value of the AdvanSure TB/NTM real-time PCR kit were, respectively, 1.7 times and 1.4 times higher in sputum-positive specimens than in sputum-negative specimens.

(출처:Abstract)

목차 Contents

• 표지 ... 1
• Abstract ... 2
• 서 론 ... 4
• 대상 및 방법 ... 5
• 1. 대상 ... 5
• 2. 연구방법 ... 5
• 3. 용어정의 ... 7
• 4. 통계분석 ... 8
• 결 과 ... 9
• 1. 대상 검체의 특징 ... 9
• 2. Anyplex MTB/NTM Real-time Detection kit과 AdvanSure TB/NTM real-time PCR kit간의 일치율 ... 10
• 3. Anyplex MTB/NTM Real-time Detection kit과 AdvanSure TB/NTM real-time PCR kit의 진단능 비교 ... 11
• 고 찰 ... 15
• 요 약 ... 17
• 참 고 문 헌 ... 18
• 끝페이지 ... 18