Abstract ▼

□ Purpose & Contents
The purpose of this research project is to establish the basis and to secure excellence of medical mathematics research for prediction, diagnosis, and treatment of diseases, and to solve problems arising inthe medical/health fields. This project includes the following topics:

□ Purpose & Contents
The purpose of this research project is to establish the basis and to secure excellence of medical mathematics research for prediction, diagnosis, and treatment of diseases, and to solve problems arising inthe medical/health fields. This project includes the following topics:
◯ Algorithm/software development and clinical application for high-definition medical images
◯ Development of biometric information-based mathematical model and disease prediction model
◯ Development of AI-based specific disease prediction model and framework using medical data
○ Mathematical modeling of the spread of infectious diseases and analysis of the effectiveness of control strategies

□ Results
◯ Algorithm/software development and clinical application for high-definition medical images
⦁ Development of algorithms for reducing arm-down noises and metal artifacts in CT images
⦁ Development of short scanning restoration techniques with performance of SSIM index of 0.87 in Brain-PET
⦁ Performance improvement and S/W development for DDH(developmental hip dysplasia) screening algorithm in X-ray images
⦁ Estimation accuracy enhancement of 49 reference points in 3D CT data rendered from MDCT
◯ Development of biometric information-based mathematical model and disease prediction model
⦁ Proof of convergence of mathematical model for LV boundary restoration
⦁ Development of machine learning-based disease prediction model and S/W using time series data of blood pressure
⦁ Development of numerical schemes for fluid flows in 2D arbitrary boundaries
⦁ Mathematical modeling for food metric-based life phenomenon and SIR type rumor spread
◯ Development of AI-based specific disease prediction model and framework using medical data
⦁ Development of prediction models with an accuracy of over 80% from the dry weight and auscultation sound data
⦁ Advancement of a model predicting (residual) agricultural product price and quantification of emotional efficacy by cosmetics
○ Mathematical modeling of the spread of infectious diseases and analysis of the effectiveness of control strategies
⦁ Analysis and spread prediction for each scenario of governmental quarantine policies against COVID-19 and related respiratory infectious diseases
⦁ Mathematical model with an accuracy more than 90% for predicting infected patients by analyzing risk factors of the regional SFTS infection

□ Expected Contribution
◯ To activate medical industry by developing mathematics based medical technologies
◯ To secure the core technology for advanced medical imaging based on mathematical theories; to reduce the dependence on foreign technology
◯ To predict the risk of regional infectious diseases using healthcare data

(source : Summary 5p)

목차 Contents

• 표지 ... 1
• 제 출 문 ... 2
• 보고서 요약서 ... 3
• 국문 요약문 ... 4
• SUMMARY ... 5
• CONTENTS ... 6
• 목차 ... 7
• 제1장. 연구개발과제의 개요 ... 8
• 제1절. 연구개발 목적 ... 8
• 제2절. 연구개발의 필요성 ... 8
• 제3절. 연구개발 범위 ... 11
• 제2장. 국내외 기술 개발 현황 ... 12
• 제1절. 해외 주요 연구기관 ... 12
• 제2절. 국내 연구 현황 ... 14
• 제3장. 연구 수행 내용 및 성과 ... 15
• 제1절. 고화질 의료영상 복원 및 분석을 위한 알고리즘 개발 및 임상 적용 ... 15
• 제2절. 인체정보 기반 수학적 모델과 질환 예측모델의 개발 ... 23
• 제3절. 의료데이터를 활용한 인공지능 기반 특정 질환 예측 모델 및 프레임워크 개발 ... 31
• 제4절. 데이터 기반 감염병 확산 수리모델링 및 방제전략 효과 분석 ... 38
• 제4장. 목표 달성도 및 관련 분야 기여도 ... 43
• 제1절. 목표 달성도 ... 43
• 제2절. 평가 착안점에 따른 자체평가 ... 45
• 제3절. 정량적 연구성과 목표 및 달성도 ... 47
• 제5장. 연구개발성과의 활용계획 ... 48
• 제6장. 연구 과정에서 수집한 해외 과학기술 정보 ... 49
• 제7장. 연구개발성과의 보안등급 ... 50
• 제8장. 국가과학기술종합정보시스템에 등록한 연구시설·장비 현황 ... 51
• 제9장. 연구개발과제 수행에 따른 연구실 등의 안전 조치 이행 실적 ... 52
• 제10장. 연구개발과제의 대표적 연구 실적 ... 53
• 제11장. 기타 사항 ... 55
• 제12장. 참고 문헌 ... 56
• 끝페이지 ... 58