There are many causes of sexual dysfunction, including primary sexual dysfunction, sexual dysfunction associated with general medical and psychiatric disorders, and sexual dysfunction associated with treatments for psychiatric disorders. Especially antidepressant-induced sexual dysfunction has emerg...
There are many causes of sexual dysfunction, including primary sexual dysfunction, sexual dysfunction associated with general medical and psychiatric disorders, and sexual dysfunction associated with treatments for psychiatric disorders. Especially antidepressant-induced sexual dysfunction has emerged as a particular problem in treatment of depression. The effect of Nelumbinis Semen on cocaine-induced genital reflexes of paradoxical sleep-deprived male rats was investigated through analyses of changes in penile erection, ejaculation and testosterone. The subjects in this study were divided into eight groups: the (-) N/C group, which wasn’t subjected to PSD for 96 hr; the (-) 500 NS group, which wasn’t subjected to PSD treated with 500 mg/kg NS for 96 hr; the (-) 1,000 NS group, which wasn’t subjected to PSD treated with 1,000 mg/kg NS for 96 hr; the CTRL group, which was subjected to PSD treated with saline for 96 hr; the (+) 500 NS group, which was subjected to PSD treated with 500 mg/kg NS for 96 hr; the (+) 1,000 NS group, which was subjected to PSD treated with 1,000 mg/kg NS for 96 hr; the (+) F group, which was subjected to PSD treated with fluoxetine hydrochloride for 96 hr; the (+) S group, which was subjected to PSD treated with St. John'S Wort for 96 hr. Rats were administered cocaine to induce spontaneous genital reflexes. The study shows that Nelumbinis Semen has very similar numbers of PE and EJ, while it has similar amounts of testosterone, compared with the control group with PSD-cocaine treatment. However, numbers of PE and EJ were significantly decreased in groups of Hypericum perforatum (St John's wort) and fluoxetine (Prozac) treatments, while they present a similar amounts of testosterone with the control group without PSD-cocaine treatment. Nelumbinis Semen has no effect on normal condition. It was concluded from the results that Nelumbinis Semen has a distinct resolution effect on sexual dysfunction, presented in commonly used anti-depressants without any side effect or toxicity for normal condition.
There are many causes of sexual dysfunction, including primary sexual dysfunction, sexual dysfunction associated with general medical and psychiatric disorders, and sexual dysfunction associated with treatments for psychiatric disorders. Especially antidepressant-induced sexual dysfunction has emerged as a particular problem in treatment of depression. The effect of Nelumbinis Semen on cocaine-induced genital reflexes of paradoxical sleep-deprived male rats was investigated through analyses of changes in penile erection, ejaculation and testosterone. The subjects in this study were divided into eight groups: the (-) N/C group, which wasn’t subjected to PSD for 96 hr; the (-) 500 NS group, which wasn’t subjected to PSD treated with 500 mg/kg NS for 96 hr; the (-) 1,000 NS group, which wasn’t subjected to PSD treated with 1,000 mg/kg NS for 96 hr; the CTRL group, which was subjected to PSD treated with saline for 96 hr; the (+) 500 NS group, which was subjected to PSD treated with 500 mg/kg NS for 96 hr; the (+) 1,000 NS group, which was subjected to PSD treated with 1,000 mg/kg NS for 96 hr; the (+) F group, which was subjected to PSD treated with fluoxetine hydrochloride for 96 hr; the (+) S group, which was subjected to PSD treated with St. John'S Wort for 96 hr. Rats were administered cocaine to induce spontaneous genital reflexes. The study shows that Nelumbinis Semen has very similar numbers of PE and EJ, while it has similar amounts of testosterone, compared with the control group with PSD-cocaine treatment. However, numbers of PE and EJ were significantly decreased in groups of Hypericum perforatum (St John's wort) and fluoxetine (Prozac) treatments, while they present a similar amounts of testosterone with the control group without PSD-cocaine treatment. Nelumbinis Semen has no effect on normal condition. It was concluded from the results that Nelumbinis Semen has a distinct resolution effect on sexual dysfunction, presented in commonly used anti-depressants without any side effect or toxicity for normal condition.
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