어린이용 영양제의 우식유발능에 관해 알아보기 위하여 국내에서 시판 중인 건강보조식품 어린이용 영양제 4종에 대한 생체외 연구를 시행하였다. 어린이용 영양제 4종을 실험군으로, 10% 자당(S)을 양성 대조군, 인공 타액(T)을 음성 대조군으로 하였다. 실험군 및 대조군의 pH를 측정하고 시료용액 50 mL의 pH를 7로 맞추는데 필요한 0.1 N NaOH의 ...
어린이용 영양제의 우식유발능에 관해 알아보기 위하여 국내에서 시판 중인 건강보조식품 어린이용 영양제 4종에 대한 생체외 연구를 시행하였다. 어린이용 영양제 4종을 실험군으로, 10% 자당(S)을 양성 대조군, 인공 타액(T)을 음성 대조군으로 하였다. 실험군 및 대조군의 pH를 측정하고 시료용액 50 mL의 pH를 7로 맞추는데 필요한 0.1 N NaOH의 부피로 완충능을 측정하였다. Streptococcus mutans의 배양액을 접종 후 12시간 배양하여 pH의 변화를 측정해서 산생성능을 살펴보았다. 하루에 2번 시료용액에 우치 법랑질 시편을 20분간 넣은 후 인공타액에 보관하는 pH 순환 모델을 8일간 적용하였고 표면미세경도의 변화를 측정하여 우치 법랑질 침식능을 검사하였다. 결과는 다음과 같다. 실험군 4종의 pH 모두 탈회 임계 pH인 5.5보다 낮았다. 완충능은 Hama Vitamin Pharm(Hamsoa Pharm Co., Korea)이 가장 크고, Smart Chewable Vitamin A(JW Pharm Co., Korea)가 가장 작았다. 4개의 실험군은 음성 대조군보다 유의하게 높은 산생성능을 보였다(p < 0.05). 우치 법랑질 침식능 검사 결과, 4종의 실험군과 양성 대조군에서 표면미세경도가 유의하게 감소하였으며, 음성 대조군은 오히려 유의하게 표면미세경도가 증가하였다(p < 0.05). 표면미세경도 감소율은 실험군 중에서 Hama Vitamin Pharm(Hamsoa Pharm Co., Korea)이 유의하게 높았고 Hikid Plus(Sanga Pharm Co., Korea)는 유의하게 낮았다(p < 0.05).
어린이용 영양제의 우식유발능에 관해 알아보기 위하여 국내에서 시판 중인 건강보조식품 어린이용 영양제 4종에 대한 생체외 연구를 시행하였다. 어린이용 영양제 4종을 실험군으로, 10% 자당(S)을 양성 대조군, 인공 타액(T)을 음성 대조군으로 하였다. 실험군 및 대조군의 pH를 측정하고 시료용액 50 mL의 pH를 7로 맞추는데 필요한 0.1 N NaOH의 부피로 완충능을 측정하였다. Streptococcus mutans의 배양액을 접종 후 12시간 배양하여 pH의 변화를 측정해서 산생성능을 살펴보았다. 하루에 2번 시료용액에 우치 법랑질 시편을 20분간 넣은 후 인공타액에 보관하는 pH 순환 모델을 8일간 적용하였고 표면미세경도의 변화를 측정하여 우치 법랑질 침식능을 검사하였다. 결과는 다음과 같다. 실험군 4종의 pH 모두 탈회 임계 pH인 5.5보다 낮았다. 완충능은 Hama Vitamin Pharm(Hamsoa Pharm Co., Korea)이 가장 크고, Smart Chewable Vitamin A(JW Pharm Co., Korea)가 가장 작았다. 4개의 실험군은 음성 대조군보다 유의하게 높은 산생성능을 보였다(p < 0.05). 우치 법랑질 침식능 검사 결과, 4종의 실험군과 양성 대조군에서 표면미세경도가 유의하게 감소하였으며, 음성 대조군은 오히려 유의하게 표면미세경도가 증가하였다(p < 0.05). 표면미세경도 감소율은 실험군 중에서 Hama Vitamin Pharm(Hamsoa Pharm Co., Korea)이 유의하게 높았고 Hikid Plus(Sanga Pharm Co., Korea)는 유의하게 낮았다(p < 0.05).
An in vitro study on cariogenic potential of 4 over-the-counter nutritional supplements for children was performed. The experimental groups were 4 over-the-counter nutritional supplements. The positive control group was 10% sucrose solution (S), and the negative control group was artificial saliva (...
An in vitro study on cariogenic potential of 4 over-the-counter nutritional supplements for children was performed. The experimental groups were 4 over-the-counter nutritional supplements. The positive control group was 10% sucrose solution (S), and the negative control group was artificial saliva (T). The pH of each group was determined. The buffering capacities were measured by the volume of 0.1 N NaOH adding to equalize the pH of 50 mL of experimental solutions to reach pH 7. The culture medium of Streptococcus mutans inoculated the experimental solutions were cultured for 12 hours. Then the pH changes of solutions, that is acid production, were measured. The bovine teeth specimens were soaked in the experimental solutions for 20 minutes two times a day. Outside those hours the specimens were stored in artificial saliva. After 8 days, the microhardness changes of the specimens were measured. The results were as follows. The pH of all experimental groups were lower than critical pH 5.5 where enamel demineralization start. The buffering capacity of the Hama Vitamin Pharm (Hamsoa Pharm Co., Korea) was highest, and the Smart Chewable Vitamin A(JW Pharm Co., Korea) had lowest buffering capacity. The reduction rates of pH of the experimental groups were significantly higher than that of the negative control group (p < 0.05). The microhardness of enamel of the all experimental groups and the positive control group significantly decreased, in contrast, the microhardness of enamel of the negative control group significantly increased after experiment (p < 0.05). The reduction rate of the microhardness of enamel of the Hama Vitamin Pharm(Hamsoa Pharm Co., Korea) was significantly higher and Hikid Plus(Sanga Pharm Co., Korea) was significantly lower than other experimental groups.
An in vitro study on cariogenic potential of 4 over-the-counter nutritional supplements for children was performed. The experimental groups were 4 over-the-counter nutritional supplements. The positive control group was 10% sucrose solution (S), and the negative control group was artificial saliva (T). The pH of each group was determined. The buffering capacities were measured by the volume of 0.1 N NaOH adding to equalize the pH of 50 mL of experimental solutions to reach pH 7. The culture medium of Streptococcus mutans inoculated the experimental solutions were cultured for 12 hours. Then the pH changes of solutions, that is acid production, were measured. The bovine teeth specimens were soaked in the experimental solutions for 20 minutes two times a day. Outside those hours the specimens were stored in artificial saliva. After 8 days, the microhardness changes of the specimens were measured. The results were as follows. The pH of all experimental groups were lower than critical pH 5.5 where enamel demineralization start. The buffering capacity of the Hama Vitamin Pharm (Hamsoa Pharm Co., Korea) was highest, and the Smart Chewable Vitamin A(JW Pharm Co., Korea) had lowest buffering capacity. The reduction rates of pH of the experimental groups were significantly higher than that of the negative control group (p < 0.05). The microhardness of enamel of the all experimental groups and the positive control group significantly decreased, in contrast, the microhardness of enamel of the negative control group significantly increased after experiment (p < 0.05). The reduction rate of the microhardness of enamel of the Hama Vitamin Pharm(Hamsoa Pharm Co., Korea) was significantly higher and Hikid Plus(Sanga Pharm Co., Korea) was significantly lower than other experimental groups.
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