국내외의 여드름에 대한 매선요법을 시행한 무작위배정 비교임상시험연구들을 고찰하여 그 치료효과에 대한 근거를 제공하고자 한다. 전자데이터베이스(KMbase, RISS, National Assembly Library, OASIS, NDSL, China Academic Journal, ...
국내외의 여드름에 대한 매선요법을 시행한 무작위배정 비교임상시험연구들을 고찰하여 그 치료효과에 대한 근거를 제공하고자 한다. 전자데이터베이스(KMbase, RISS, National Assembly Library, OASIS, NDSL, China Academic Journal, Pubmed, Science direct)에서 2016년 08월까지 국문, 영문, 중문으로 작성된 논문을 검색하였다. 초록과 본문을 통해 선정기준에 맞는 무작위배정 비교임상시험연구들은 선택하여 자료들을 추출하고 분석하였다. 비뚤림 위험평가는 Cochrane’s Risk of Bias(RoB)를 사용하였다. 그 결과, 총 23편의 무작위배정비교임상시험연구가 문헌고찰에 포함되었고, 91.3%의 연구가 최근 10년 내에 이루어졌다. 87%의 연구에서 실험군이 더 유의한 효과를 나타내었고, 사용된 혈위는 肺兪가 91.3%로 가장 많이 사용되었고, 평균 8.7개의 혈위를 사용하였다. 82.6%에서 羊肠线을 사용하였으며, 10~20mm의 길이를 사용하였다. 치료간격은 평균 13.1일, 치료횟수는 4.9회였다. 비뚤림 위험평가에서 무작위 배정순서 항목 high risk of bias 2편, low risk of bias 8편, unclear risk of bias 13편, 배정순서 은폐 high risk of bias 8편, low risk of bias 1편, unclear risk of bias 14편, 연구 참여자, 연구자에 대한 눈가림 low risk of bias 2편, unclear risk of bias 21편, 결과평과에 대한 눈가림 low risk of bias 23편, 불충분한 결과자료 low risk of bias 10편, unclear risk of bias 13편, 선택적 보고와 그 외 비뚤림 항목에서 unclear risk of bias 23편으로 분류하였다. 매선요법의 여드름에 대한 치료 효과를 증명하기 위한 23편의 무작위배정 비교임상시험연구에서 전체적으로, 부분적으로 유의한 결과를 얻었음을 확인하였다. 그러나 대부분의 연구가 다수의 비뚤림 위험에 노출되어 있어 추후 더욱 질 높은 연구가 필요하다.
국내외의 여드름에 대한 매선요법을 시행한 무작위배정 비교임상시험연구들을 고찰하여 그 치료효과에 대한 근거를 제공하고자 한다. 전자데이터베이스(KMbase, RISS, National Assembly Library, OASIS, NDSL, China Academic Journal, Pubmed, Science direct)에서 2016년 08월까지 국문, 영문, 중문으로 작성된 논문을 검색하였다. 초록과 본문을 통해 선정기준에 맞는 무작위배정 비교임상시험연구들은 선택하여 자료들을 추출하고 분석하였다. 비뚤림 위험평가는 Cochrane’s Risk of Bias(RoB)를 사용하였다. 그 결과, 총 23편의 무작위배정비교임상시험연구가 문헌고찰에 포함되었고, 91.3%의 연구가 최근 10년 내에 이루어졌다. 87%의 연구에서 실험군이 더 유의한 효과를 나타내었고, 사용된 혈위는 肺兪가 91.3%로 가장 많이 사용되었고, 평균 8.7개의 혈위를 사용하였다. 82.6%에서 羊肠线을 사용하였으며, 10~20mm의 길이를 사용하였다. 치료간격은 평균 13.1일, 치료횟수는 4.9회였다. 비뚤림 위험평가에서 무작위 배정순서 항목 high risk of bias 2편, low risk of bias 8편, unclear risk of bias 13편, 배정순서 은폐 high risk of bias 8편, low risk of bias 1편, unclear risk of bias 14편, 연구 참여자, 연구자에 대한 눈가림 low risk of bias 2편, unclear risk of bias 21편, 결과평과에 대한 눈가림 low risk of bias 23편, 불충분한 결과자료 low risk of bias 10편, unclear risk of bias 13편, 선택적 보고와 그 외 비뚤림 항목에서 unclear risk of bias 23편으로 분류하였다. 매선요법의 여드름에 대한 치료 효과를 증명하기 위한 23편의 무작위배정 비교임상시험연구에서 전체적으로, 부분적으로 유의한 결과를 얻었음을 확인하였다. 그러나 대부분의 연구가 다수의 비뚤림 위험에 노출되어 있어 추후 더욱 질 높은 연구가 필요하다.
The author has attempted to provide the basis of treatment effects by considering foreign and domestic randomized controlled trials (RCTs), being implemented with Thread Embedding Acupuncture for Acne vulgaris. The literature prepared in Korean, English and Chinese by August, 2016 were found in ...
The author has attempted to provide the basis of treatment effects by considering foreign and domestic randomized controlled trials (RCTs), being implemented with Thread Embedding Acupuncture for Acne vulgaris. The literature prepared in Korean, English and Chinese by August, 2016 were found in electronic database (KMbase, RISS, National Assembly Library, OASIS, NDSL, China Academic Journal, Pubmed, Science Direct). The foreign and domestic RCTs were chosen by selection criteria through abstracts and articles with the data then subsequently being extracted and analyzed. Cochrane’s Risk of Bias Tool was used for the risk of bias. The total of 23 randomly assigned foreign and domestic comparative clinical trial studies were included in the review, 91.3% of studies were accomplished within the last decade. The experimental group has shown more significant effects in 87% of studies. The most frequent acupoint was BL13 and it was used in 91.3% with average 8.7 acupoints. Catguts were used in 82.6%, and the most frequent length was a range of 10-20mm. The interval of treatment was an average of 13.1days with 4.9 average treatment frequencies. The studies of risk of bias were classified according to 2 high risk of bias, 8 low risk of bias, 13 unclear risk of bias by randomly sequence generation; 8 high risk of bias, 1 low risk of bias, 14 unclear risk of bias by allocation concealment; 2 low risk of bias, 21 unclear risk of bias by blinding of participant and personnel; 23 low risk of bias by blinding outcome assessment; 10 low risk of bias, 13 unclear of bias by incomplete outcome data and 2 unclear risk of bias by selective reporting and other bias. Overall and partial significant results were obtained from 23 foreign & domestic comparative RCTs which substantiates the treatment effects of Thread Embedding Acupuncture for Acne vulgaris. Since all studies, however, were exposed to the risk of bias, so future research of higher quality shall be necessary.
The author has attempted to provide the basis of treatment effects by considering foreign and domestic randomized controlled trials (RCTs), being implemented with Thread Embedding Acupuncture for Acne vulgaris. The literature prepared in Korean, English and Chinese by August, 2016 were found in electronic database (KMbase, RISS, National Assembly Library, OASIS, NDSL, China Academic Journal, Pubmed, Science Direct). The foreign and domestic RCTs were chosen by selection criteria through abstracts and articles with the data then subsequently being extracted and analyzed. Cochrane’s Risk of Bias Tool was used for the risk of bias. The total of 23 randomly assigned foreign and domestic comparative clinical trial studies were included in the review, 91.3% of studies were accomplished within the last decade. The experimental group has shown more significant effects in 87% of studies. The most frequent acupoint was BL13 and it was used in 91.3% with average 8.7 acupoints. Catguts were used in 82.6%, and the most frequent length was a range of 10-20mm. The interval of treatment was an average of 13.1days with 4.9 average treatment frequencies. The studies of risk of bias were classified according to 2 high risk of bias, 8 low risk of bias, 13 unclear risk of bias by randomly sequence generation; 8 high risk of bias, 1 low risk of bias, 14 unclear risk of bias by allocation concealment; 2 low risk of bias, 21 unclear risk of bias by blinding of participant and personnel; 23 low risk of bias by blinding outcome assessment; 10 low risk of bias, 13 unclear of bias by incomplete outcome data and 2 unclear risk of bias by selective reporting and other bias. Overall and partial significant results were obtained from 23 foreign & domestic comparative RCTs which substantiates the treatment effects of Thread Embedding Acupuncture for Acne vulgaris. Since all studies, however, were exposed to the risk of bias, so future research of higher quality shall be necessary.
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