선택한 단어 수는 입니다.
최소 단어 이상 선택하여야 합니다.
최소 단어 이상 선택하여야 합니다.
선택한 단어 수는 30입니다.
최대 10 단어까지만 선택 가능합니다.
최대 10 단어까지만 선택 가능합니다.
문제 정의
- Therefore, the purpose of this study is to find out that, using the inositol and phytic acid which show sim ilar structures and have mutual effects, feasibility of inositol and phytic acid as a new functional ingredients in cosmetics is examined. Skin lotions containing ino sitol and phytic acid were prepared, applied on skin, and its effects on moisture, sebum, elasticity, and wrin kling of skin were evaluated.
제안 방법
- 10 wt%) were applied on the area below the right eye twice a day. After seven weeks application of the lotion, the repli cas were retraced and analyzed by Image Analyzer (KIT-500, PIAS, Japan). Effects of the skin lotion on number, depth, length, and width of the wrinkles were quantitatively analyzed[12].
- In this study of the effects on the moisture, sebum, elasticity, and wrinkle of skin with the use of inositol and phytic acid skin lotions, the following conclusions were obtained.
- Inositol (1.0 wt%) and different concentrations of phytic acid (0.05, 0.10, 0.15, and 0.20 wt%), 0.2 wt% allantoin, 0.05 wt% EDTA-2Na, 0.1 wt% germall, and 8.0 wt% glycerin were successively added in a beaker containing 80 wt% distilled water. An agitation mixer was used to obtain a homogeneous solution.
- Therefore, the purpose of this study is to find out that, using the inositol and phytic acid which show sim ilar structures and have mutual effects, feasibility of inositol and phytic acid as a new functional ingredients in cosmetics is examined. Skin lotions containing ino sitol and phytic acid were prepared, applied on skin, and its effects on moisture, sebum, elasticity, and wrin kling of skin were evaluated.
- The inositol (1.0 wt%) and phytic acid (0.05, 0.10, 0.15, and 0.20 wt%) skin lotions were evenly applied on the specific areas of the subjects both arms twice a day. The subjects were located in a constant temper ature and humidity room for 20 min prior to moisture evaluation to minimize effect of atmospheric conditions on the measurement.
- Elleven of them had dry skin and others had oily skin. The inositol and phytic acid skin lotions with various concentrations were applied each morning and evening after washing for seven weeks on specific area of face, cheek, and arm of the subjects. Moisture effect on arm was measured after applying the inositol (1.
- The measurement was carried out 30 min after applying the skin lotion on cheek area located 5 cm below the subjects eye. The measurement was made each week during a period of seven weeks by using Cutometer (SEM474, Courage + Kha^aka, Ger many) with three replications.
- Therefore, the subjects' skin with the sebum values below or equal to 80 g/cm2 was designated as dry skin, the skin with the sebum values above or equal to 150 g/cm2 were assigned as oily skin. The sebum values were evaluated for the placebo, inositol (1.0 wt%), phytic acid (0.50 wt%), and inositol (1.0 wt%) phytic acid (0.10 wt%) skin lotions, respectively.
- 20 wt%) skin lotions were evenly applied on the specific areas of the subjects both arms twice a day. The subjects were located in a constant temper ature and humidity room for 20 min prior to moisture evaluation to minimize effect of atmospheric conditions on the measurement. Comeometer (CM820PC, Courage + Khazaka, Germany) was used to measure the mois- ture.
- The values of skin elasticity were evaluated for the placebo, inositol (1.0 wt%), phytic acid (0.50 wt%), and inositol (1.0 wt%)-phytic acid (0.1 wt%) skin lotions for seven weeks.
대상 데이터
- The measurements were made on center of forehead and cheek area located 2 cm below the subjects eye. Seb- umeter (SM80, Courage + Khazaka, Germany) was used.
- Subjects used were 15 healthy Asian women (20 ~ 30's and 40~50's). Elleven of them had dry skin and others had oily skin.
성능/효과
- 1. The moisture values were 66.9, 92.7, and 93.0 for the inositol (1.0 wt%), the phytic acid (0.50 wt%), and the inositol (1.0 wt%)-phytic acid (0.10 wt%) skin lotion, respectively. The increasing rate of moisture were 19%, 71.
- 2. In the sebum value, the time needed for the dry or oily skin to be changed into the neutral 아dn were 4 weeks and 2 weeks for the inositol (1.0 wt%) and phytic acid (0.50 wt%) skin lotion, and the inositol (1.0 wt%)-phytic acid (0.10 wt%) skin lotion, respectively.
- 3. The improvements of skin elasticity on 20~30 ages were 9%, 13%, and 18% for the inositol (1.0 wt%), the phytic acid (0.50 wt%), and the inositol (1.0 wt%)- phytic acid (0.10 wt%) skin lotions, respectively. Its values on 40~50 ages were 17.
- 4. The total improvement on the peak, length, depth, and width were 12.5%, 16.9%, and 17.4% for the ino sitol (1.0 wt%), the phytic acid (0.50 wt%), and the ino sitol (1.0 wt%)-phytic acid (0.10 wt%) skin lotion, respectively.
- And then its value did not show the further increasment. After four weeks the sebum values were 114, 105, and 113.7 g/cm2 for the inositol (1.0 wt%), the phytic acid (0.50 wt%), and the inositol (1.0 wt%)-phytic acid (0.10 wt%) skin lotions, respectively. With these results it took 4 weeks more for the im provement of skin by the inositol (1.
- 3%, respectively, the values of length, depth, and width are much more higher than that of peak. Although, there was a wide difference in the individual improvement according to the subjects like as in Table 1, the total improvement were 124%, which illustrats much greater improvement in wrikle than that of the placebo skin lotion.
- 70 constantly. The increase of moisture revealed 19%, With the phytic acid (0.50 wt%) skin lotion the initial moisture value was 54 and its value increased continuously to 70, 83, and 86 for one week, two weeks, and three weeks, respectively, and then after four weeks a value of 92 held constantly. And the increase of moisture was 71.
- However, compared to Table 2 the differ ences in the individual improvement according to the subjects reveal small. The total improvement was 16.9 %, which also illustrates much greater improvement in wrinkle than that of the inositol (1.0 wt%) skin lotion.
- Evaluation param eters on skin wrinkles were peak (number of wrinkles), length, depth, and width. Total wrinkle improvement value was obtained by calculating combining effects of four parameters, such as peak, length, depth, and width of wrinkles, with putting the different weight on the factor; 30%, for peak; 20%, for length; 30%, for depth; 20% for width, respectively.
- With the foregoing results, since the problems on using the phytic acid only can be reduced, it can be concluded that, with using the inositol and phytic acid simultaneously, the inositol (1.0 wt%)-phytic acid (0.10 wt%) skin lotion is more beneficial than any other skin lotions in our experiments.
- With the results in Tables 2, 3, and 4, it may be concluded that the use of the inositol (1.0 wt%)-phytic acid (0.10 wt%) skin lotion is more beneficial than that of the placebo, the inositol (1.0 wt%), and the phytic acid (0.50 wt%) skin lotions on the wrinkle improve ment, and especially shows more effectiveness in the peak.
- 10 wt%) skin lotions, respectively. With these results it took 4 weeks more for the im provement of skin by the inositol (1.0 wt%) and phytic acid (0.50 wt%) skin lotions, but in the case of the inositol (1.0 wt%)-phytic acid (0.10 wt%) skin lotion, only 2 weeks were needed. Hence, for the improvement of skin the using with inositol and phytic acid simul- taneously could take less time for the improvement of skin than that of inositol and phytic acid, individually.
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