[논문]건강한 성견의 canine coronavirus에 대한 항체가 조사

안소저; 정석영; 박선일; 김두

[국내논문] 건강한 성견의 canine coronavirus에 대한 항체가 조사
Serologic Survey for Canine Coronavirus in Adult Dogs 원문보기

Journal of veterinary clinics = 한국임상수의학회지, v.24 no.4 = no.59, 2007년, pp.493 - 498

안소저 (강원대학교 수의학부대학) , 정석영 (강원대학교 수의학부대학) , 박선일 (강원대학교 수의학부대학) , 김두 (강원대학교 수의학부대학)

초록
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건강한 성견들의 혈청 CCV 항체 역가 보유실태와 역학적인 요인들과 관련성을 조사하기 위하여, 2003년 1월부터 2004년 4월까지 국내의 1세 이상된 성견 812두를 대상으로 CCV에 대한 중화항체 역가를 조사하였으며 연령, 성별, 사육지역, 사육환경 및 기초 예방접종과 추가 예방접종 여부 등의 역학적 요인들 별로 항체보유 상태를 조사하였다. 조사대상 812두의 성견 중 87.9%(714두)가 CCV에 대하여 항체 양성(1:4 이상) 반응을 보였다. 연령, 성별, 사육지역, 사육상태 및 예방접종 상태는 항체보유율에 영향을 미치지 않았으나 나아가 증가함에 따라 항체 보유율이 증가하는 양상을 보였다. 이상의 결과를 종합해볼 때, 국내의 성견들은 CCV에 대하여 항체보유율이 대체로 높은 수준이었으며 CCV 감염이 전국에 걸쳐 발생하는 것으로 판단되므로 개들의 CCV에 대한 방어를 위하여 위생적인 관리와 함께 예방접종이 필요한 것으로 생각되었다.

Abstract ▼ AI-Helper

The purposes of this study were to survey the seroprevalence of canine coronavirus(CCV) in healthy adult dogs and to determine whether there was any relationship between seroprevalence and the host parameters. Serum samples for determination of serum neutralization antibody titers against CCV were obtained from 812 healthy adult dogs over 1 year old brought to veterinary clinics for routine health care visit in 4 provinces from January 2003 to April 2004. Of the 812 dogs, 714(87.9%) had positive antibody titers(more than 1:4) against CCV. The prevalence of positive CCV antibody titers were not significantly associated with age, sex, rearing province and environment, and vaccination status. However, the positive CCV antibody titers were increasing with the age. These serological findings have shown that prevalence of positive CCV antibody titers in Korean dogs were a relatively high and that CCV infection was widespread in Korean dog population. These suggest that it may be as important to protect dogs against infection with CCV as it is to vaccinate against canine parvovirus.

주제어

AI 본문요약
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문제 정의

Furthermore, it is not clear how many widespread CCV infection is in dogs in Korea nowadays. The purposes of this study were to survey the seroprevalence of CCV in healthy adult dogs and to determine whether there was any relationship between seroprevalence and the host parameters.

제안 방법

Serological test result and potential associations with age, sex, breed, rearing environment and province, primary vaccination, and revaccination were assessed by the use of a Chi- square test and Cochran-Mantel-Haenszel trend test. All of the analyses described above were performed using SAS version 9.
Serum CCV antibody titer was determined by the SN test as described by Barlough et al (3), with minor modification. Pnor to use, all test sera were heated to 56℃ for 30 minutes in order to inactivate heat-labile virus inhibitors.

대상 데이터

SN titers : SN antibody titers against CCV of 812 adult dogs were evaluated. Of the 812 dogs, 714 (87.

성능/효과

9%(11). In this study we found that a high percentage (87.9%) of health adult dogs had antibodies against CCV This high rate of serum positivity was considered by natural active infection and CCV vaccination.
These serological findings have shown that prevalence of positive CCV antibody titers in Korean dogs were a relatively high and that CCV infection was widespread in Korean dog population. These suggest that it may be as important to protect dogs by vaccination with CCV as it is to vaccinate against CPV

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