선택한 단어 수는 입니다.
최소 단어 이상 선택하여야 합니다.
최소 단어 이상 선택하여야 합니다.
선택한 단어 수는 30입니다.
최대 10 단어까지만 선택 가능합니다.
최대 10 단어까지만 선택 가능합니다.
제안 방법
- 5mg/Kg of BV or 30以 and 10mg/ Kg of morphine was injected into a hind paw of mice intraplantarly 30minutes before pain was induced by 10 nmol of capsaicin. Lick phenomenon was observed from 30 to 40minutes after baseline(from right after pain was induced to 10 minutes after pain induction), and then Hot Plate test was performed with the hot plate unit from 40 to 45minutes after baseline, and last Tail Flick test was followed from 45 to 60minutes after baseline. Each value means 士 S.
- 5mg/Kg of BV or 30成 and 10mg/ Kg of morphine was injected intc> a hind paw of mice intraplantarly 30minutes before pain was induced by 10 nmol of capsaicin. Lick phenomenon was observed from 30 to 40minutes after bas신ine(from right after pain was induced to 10 minutes after pain induction), and then Hot Plate test was performed with the hot plate unit from 40 to 45minutes after baseline, and last Tail Flick test was followed from 45 to 60minutcs after baseline. In spontaneous nociceptive behaviour test, LN of BV or Morphine significantly decreased by capsaicin was 9.
- of bradykinin treated. Lick phenomenon was observed from baseline(right after pain induction) to lOminutes after pain induction, and then Hot Plate test was performed with the hot plate unit from lOminutes after pain induction to 15minutes after pain induction, and last Tail Flick test was followed from 15minutes after pain induction to 30minutes after pain induction. In spontaneous nociceptive behaviour test, LN significantly increased by Capsaicin or Bradykinin was 20.
- The behavioral test was performed with the tail flick unit from 15minutes after pain induction to 30 minutes after pain induction in the absence of BV or morphine pre-treatment, while it was performed from 45 to 60minutes after baseline in the presence of BV or morphine pre-treatment. Experimental rats were properly fitted in plastic holders with their tails protruding outside and were allowed to adapt to the environment for 60 min/day for 7days.
- this test was performed with the hot plate unit from lOminutes after pain induction to 15 minutes after pain induction in the absence of BV or morphine pre-treatment, while it was performed from 40 to 45minutes after baseline in the presence of BV or morphine pre-treatment.
데이터처리
- Data were analyzed using one-way analysis of variance followed by Tuckey test as a post hoc test. Differences were considered significant at p<0.
이론/모형
- All mice were housed in a room that was automatically maintained at 21~25℃ and relative humidity (45~ 65%) with a controlled light-dark cycle. All experiments were conducted in accordance with the guidelines of the International Association for the Study of Pain (IASP)9).
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