선택한 단어 수는 입니다.
최소 단어 이상 선택하여야 합니다.
최소 단어 이상 선택하여야 합니다.
선택한 단어 수는 30입니다.
최대 10 단어까지만 선택 가능합니다.
최대 10 단어까지만 선택 가능합니다.
가설 설정
- 12. Product satisfaction was higher in the experimental group than in the control group.
제안 방법
- After six weeks, the subjects and the research investigator evaluate an improvement degree and also the subjects evaluate a satisfactory degree divided at 5 phases(Table 2).
- Aim of this studies used the SCORAD Index with first effectiveness evaluation using in the subjects ‘Atomento solution & cream’ for evaluates the condition improvement of the atopic dermatitis.
- The subjects are tested through double blinding, block randomization and then divided into the experimental group and the control group. For six weeks of test period, gross examination, hematological examination and instrumentation through skin-ANBT equipment were made before and after the experiments to see how well the products for experimental group act against the disease compared with those for control group in recovering the damaged skin barriers by atopic dermatitis.
- In order to examine the effect where the product which it uses on the human body conduct an experiment with the blood analysis(WBC, RBC, MCV, MCH, MCHC, MPV, Hemoglobin, Hematocrit and Platelets count) and biochemical analysis (Total Bilirubin, Glucose, AST, ALT, ALP, Albumin, BUN, Total Protein, Creatinine, Na, K, Cl and Total Cholesterol and ESR).
- In order to examine the effect where the product which it uses on the human body conduct an experiment with the blood analysis(WBC, RBC, MCV, MCH, MCHC, MPV, Hemoglobin, Hematocrit and Platelets count) and biochemical analysis (Total Bilirubin, Glucose, AST, ALT, ALP, Albumin, BUN, Total Protein, Creatinine, Na, K, Cl and Total Cholesterol and ESR).
- Skin change of before and after of evaluation tested in order to evaluate measured in skin moisture content by using Corneometer CM825(Courage+Khazaka electronic GmbH, Germany).
- The clinical research here was done to atopic dermatitis patients from 5 to 50 years of age who were diagnosed as having the disease by the Atopic Dermatitis Research Group in 2005 and who have no histories of medicinal treatments or external preparation13). The subjects are tested through double blinding, block randomization and then divided into the experimental group and the control group. For six weeks of test period, gross examination, hematological examination and instrumentation through skin-ANBT equipment were made before and after the experiments to see how well the products for experimental group act against the disease compared with those for control group in recovering the damaged skin barriers by atopic dermatitis.
대상 데이터
- After a series of prior notices for the clinical research, the subjects of this study were selected from the patients who have been diagnosed as having atopic dermatitis by OMDs in Dept. of Oriental Medical Ophthalmology & Otolaryngology & Dermatology of Semyung Jecheon Oriental Medical Hospital, Korea.
데이터처리
- Comparison between two groups were analyzed using Student's t-test.
이론/모형
- 05 considered be statistically significant. Independent sample T verification method and Confrontation sample T official approval method were used by Statistical analysis method. the baseline characteristics was analyzed by frequency analysis and descriptive analysis
성능/효과
- 1. The total number of subjects was 30: in the experimental group, 4 were males and 12 were females in the control group, 4 were males and 10 were females.
- 3. In the atopic dermatitis diagnostic criteria, both the control group and the experimental group have more than two major features and four minor features. In minor features of the experimental group and the control group, xerosis was the most common symptom followed by the tendency towards non-specific hand or foot dermatitis, scalp scale, periorbital eczema or orbital darkening etc.
- 4. In the primary endpoint, SCORAD Index showed a statistically significant (reliable) decline in both the control group and the experimental group. However, the experimental group showed greater statistical significance (reliability) than the control group.
- 5. In the secondary endpoint index of skin hydration, both the control group and the experimental group showed a statistically significant (reliable) increase. However, the degree of skin hydration in the experimental group is greater than in the control group.
- 6. In the secondary endpoint index of Transepidermal Water Loss (TEWL), the statistical significance (reliability) of the control group was acknowledged but TEWL increased; TEWL of the experimental group showed a statistically significant (reliable) decline.
- 9. In the secondary endpoint index of Eosinophil count, compared to the previous level, both the control group and the experimental group showed a statistically significant (reliable) decline it was higher in the experimental group than in the control group.
- In the secondary endpoint index of skin pH, both the control group and the experimental group are located on the edges of subacid and alkalescent states. After six weeks, the skin pH in the control group was higher than in the experimental group, showing no statistical significance (reliability).
- Throughout the clinical research for six weeks, ‘Atomento solution & cream’ proved their efficacy on the damaged skin barriers and also verified the high moisturizing effects for atopic dermatitis.
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