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한국식품과학회지 = Korean journal of food science and technology, v.44 no.2, 2012년, pp.141 - 147
이재익 (고려대학교 식품생명공학과) , 김영완 (고려대학교 식품생명공학과)
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Biogenic amines have been used as chemical indicators to estimate bacterial spoilage of foods, particularly fish and fish products, cheese, and fermented foods. So far many chromatography methods have been developed to detect biogenic amines in foods. Although these instrumental analyses exhibit goo...
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| 핵심어 | 질문 | 논문에서 추출한 답변 |
|---|---|---|
| 대표적인 BA 검출을 위해서 상용화된 신속검출법은 무엇인가? | 현재 BA 검출을 위해서 상용화된 신속검출법은 효소면역 분석법(enzyme-linked immunosorbent assay, ELISA)이 대표적이다. ELISA는 항원 또는 항체에 효소, 주로 고추냉이에서 유래한 퍼옥시데이즈(horseradish peroxidase, HRP)를 중합시킨 후, 효소의 활성을 이용하여 항체와 항원의 결합 정도를 정량적으로 측정하는 방법이다. | |
| 바이오제닉아민이란 무엇인가? | 바이오제닉아민(Biogenic amine, BA)은 아미노산의 탈탄산작용 또는 알데하이드와 케톤의 아미노화와 아미노기 전이반응에 의해 주로 생성되는 질소화합물이다(1). BA는 아민그룹의 개수에 따라 모노아민류(monoamines), 다이아민류(diamines) 및 폴리아민류(polyamines)로 분류하며(Fig. | |
| 바이오제닉아민은 어떻게 분류할 수 있는가? | 바이오제닉아민(Biogenic amine, BA)은 아미노산의 탈탄산작용 또는 알데하이드와 케톤의 아미노화와 아미노기 전이반응에 의해 주로 생성되는 질소화합물이다(1). BA는 아민그룹의 개수에 따라 모노아민류(monoamines), 다이아민류(diamines) 및 폴리아민류(polyamines)로 분류하며(Fig. 1), 화학적 구조에 의해서는 지방 족화합물(putrescine(Put), cadaverine(Cad), spermine(Spm), spermidine(Spd)), 방향족화합물(tyramine(TyrN), 2-phenylethylamine(PheN)) 및 헤테로환상화합물(histamine(HisN), tryptamine(TrpN))로 나눌 수 있다. BA은 세포 내에서 세포증식, 분화 및 성장에 중요한 역할을 수행하며(2), 체내에서 직간접적으로 신경전달물질로서 작용하고, 혈압조절 및 혈류 등의 심혈관계에도 영향을 미친다(3). |
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