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Ubiquitin E3 ligases controlling p53 stability 원문보기

Animal cells and systems, v.16 no.3, 2012년, pp.173 - 182  

Lee, Seong-Won (School of Biological Sciences, Seoul National University) ,  Seong, Min-Woo (School of Biological Sciences, Seoul National University) ,  Jeon, Young-Joo (School of Biological Sciences, Seoul National University) ,  Chung, Chin-Ha (School of Biological Sciences, Seoul National University)

Abstract AI-Helper 아이콘AI-Helper

The p53 protein plays a pivotal role in tumor suppression. The cellular level of p53 is normally kept low by proteasome-mediated degradation, allowing cell cycle progression and cell proliferation. Under stress conditions, such as DNA damage, p53 is stabilized and activated through various post-tran...

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참고문헌 (118)

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