[논문]Sensitivity Alterable Biosensor Based on Gated Lateral BJT for CRP Detection

Yuan, Heng; Kang, Byoung-Ho; Lee, Jae-Sung; Jeong, Hyun-Min; Yeom, Se-Hyuk; Kim, Kyu-Jin; Kwon, Dae-Hyuk; Kang, Shin-Won

doi:10.5573/jsts.2013.13.1.001

Sensitivity Alterable Biosensor Based on Gated Lateral BJT for CRP Detection 원문보기

Journal of semiconductor technology and science, v.13 no.1, 2013년, pp.1 - 7

Yuan, Heng (School of Electrical Engineering and Computer Science, Kyungpook National University) , Kang, Byoung-Ho (Center for Functional Devices Fusion Platform, Kyungpook National University) , Lee, Jae-Sung (School of Electrical Engineering and Computer Science, Kyungpook National University) , Jeong, Hyun-Min (School of Electrical Engineering and Computer Science, Kyungpook National University) , Yeom, Se-Hyuk (Center for Functional Devices Fusion Platform, Kyungpook National University) , Kim, Kyu-Jin (School of Electrical Engineering and Computer Science, Kyungpook National University) , Kwon, Dae-Hyuk (Department of Electronic Engineering, Kyungil University) , Kang, Shin-Won (School of Electronics Engineering, College of IT Engineering, Kyungpook National University)

Abstract ▼ AI-Helper

In this paper, a biosensor based on a gated lateral bipolar junction transistor (BJT) is proposed. The gated lateral BJT can function as both a metal-oxide-semiconductor field-effect transistor (MOSFET) and a BJT. By using the self-assembled monolayer (SAM) method, the C-reactive protein antibodies were immobilized on the floating gate of the device as the sensing membrane. Through the experiments, the characteristics of the biosensor were analyzed in this study. According to the results, it is indicated that the gated lateral BJT device can be successfully applied as a biosensor. Additionally, we found that the sensitivity of the gated lateral BJT can be varied by adjusting the emitter (source) bias.

주제어

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가설 설정

In this study, we proposed a new type of CRP biosensor based on a gated lateral BJT. The fabrication of the sensor utilized the common semiconductor manufacturing technology (0.

제안 방법

By fabricating a floating gate on the lateral BJT, the gated lateral BJT was formed; it can be used as a sensor for ion detection and gas sensing [10, 11]. According to the experiment, the proposed gated lateral BJT operated in the MOSFET-BJT hybrid mode can be used as a biosensor and the sensitivity can be controlled by input biases.
Unlike common MOSFETs, the gated lateral BJT can be operated in multiple modes, including a typical MOSFET mode, a typical BJT mode, and a MOSFET-BJT hybrid mode. For this study, the lateral collector (drain) and p-substrate of the device were connected to the ground, and a positive bias was applied to the emitter (source). The operational modes can be switched using the gate bias and base current supply, i.
In this study, we propose a new type of semiconductor CRP biosensor based on a gated lateral bipolar junction transistor (BJT) whose sensitivity can be changed by adjusting the emitter (source) bias supply. The device was fabricated using a standard CMOS process, with the advantages of having a small size and being easy to manufacture.

대상 데이터

It consists of a semiconductor test & analyzer (STA), a gated lateral BJT device (embedded on a printed circuit board), a text fixture, and a PC.

성능/효과

According to the results, when VE was equal to 0.5 V, 0.6 V, 0.7 V, 0.8 V, and 0.9 V, the sensitivity of the gated lateral BJT device for CRP detection was approximately 0.80, 1.00, 1.13, 1.29, and 1.35 µA/decade, respectively.

참고문헌 (15)

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