$\require{mediawiki-texvc}$
  • 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"

논문 상세정보

Abstract

Objective : Panic disorders are frequently accompanied by major depressive disorder (MDD). There is insufficient information about which clinical factors in panic disorder are associated with comorbid MDD. The aim of this study is to identify clinical factors related with comorbid MDD in patients with panic disorder. Methods : Two experienced psychiatrists diagnosed panic disorder based on DSM-IV criteria. This diagnosis in the 275 subjects was confirmed again by Mini-International Neuropsychiatric Interview (MINI). Lifetime comorbid psychiatric diagnoses were examined by MINI. The Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA) and Panic Disorder Severity Scale (PDSS) were used to assess the severity of depressive, anxiety and panic symptoms. Results : The result of MINI showed that 95 patients (34%) with panic disorder satisfied the diagnosis of MDD. Multivariate logistic regression model showed that comorbid generalized anxiety disorder (GAD) and the symptom of "fear of losing control or going crazy" were associated with MDD in patients with panic disorder. In female patients, the "chills or hot flushes" symptom was also associated with comorbid MDD. Conclusion : These results showed that coexisting GAD and certain symptoms of panic are associated with comorbid MDD.

질의응답 

키워드에 따른 질의응답 제공
핵심어 질문 논문에서 추출한 답변
공황 장애 집단에서 동반된 주요 우울증
공황 장애 집단에서 동반된 주요 우울증은 공황장애만 있는 집단에 비해 더 심각한 우울, 불안, 공황 증상을 보였고, 범불안장애의 동반과 특정 공황증상의 호소가 많음이 시사하는 바는 무엇인가?
특정 공황증상이 주요 우울증, 공황증상의 병태 생리학적 유사성과 주요 우울증의 인지왜곡적 측면을 나타낼 가능성을 시사한다

공황 장애 집단에서 동반된 주요 우울증은 공황장애만 있는 집단에 비해 더 심각한 우울, 불안, 공황 증상을 보였고, 범불안장애의 동반과 특정 공황증상(“자제력 상실, 미칠 것 같은 느낌”, “오한 또는 얼굴이 화끈 달아오름”)의 호소가 많았다. 이러한 결과는 특정 공황증상이 주요 우울증, 공황증상의 병태 생리학적 유사성과 주요 우울증의 인지왜곡적 측면을 나타낼 가능성을 시사한다.

공황장애
공황장애란 무엇인가?
반복적인 공황발작을 특징으로 하는 불안장애

공황장애는 반복적인 공황발작을 특징으로 하는 불안장애로 전체 인구에서 약 1~3%의 유병률을 보이고, 1 일차 의료기관에 내원한 환자의 3~8%가 이 질환을 가진다. 2,3 주요 우울증 (major depressive disorder, 이하 MDD)은 약 13%의 평생유병률을 보이는 질환으로, 4 전 세계적으로 장애손실년수(years of life lived with disability)의 가장 큰 원인이며, 2020년에 이르면 남/여 모두에서 심장질환에 이어 장애-보정 생존년수 Anxiety and Mood Vol 10, No 1 (disability-adjusted life years)에 두 번째로 영향을 줄 것이라 추정된다.

공황장애
공황장애의 유병률은 어느 정도인가?
전체 인구에서 약 1~3%의 유병률

공황장애는 반복적인 공황발작을 특징으로 하는 불안장애로 전체 인구에서 약 1~3%의 유병률을 보이고, 1 일차 의료기관에 내원한 환자의 3~8%가 이 질환을 가진다. 2,3 주요 우울증 (major depressive disorder, 이하 MDD)은 약 13%의 평생유병률을 보이는 질환으로, 4 전 세계적으로 장애손실년수(years of life lived with disability)의 가장 큰 원인이며, 2020년에 이르면 남/여 모두에서 심장질환에 이어 장애-보정 생존년수 Anxiety and Mood Vol 10, No 1 (disability-adjusted life years)에 두 번째로 영향을 줄 것이라 추정된다.

질의응답 정보가 도움이 되었나요?

참고문헌 (37)

  1. 1. Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S, et al. Lifetime and 12-month prevalence of dsm-iii-r psychiatric disorders in the united states. Results from the national comorbidity survey. Arch Gen Psychiatry 1994;51:8-19. 
  2. 2. Spitzer RL, Kroenke K, Linzer M, Hahn SR, Williams JB, deGruy FV 3rd, et al. Health-related quality of life in primary care patients with mental disorders. Results from the prime-md 1000 study. JAMA 1995;274:1511-1517. 
  3. 3. Leon AC, Olfson M, Broadhead WE, Barrett JE, Blacklow RS, Keller MB, et al. Prevalence of mental disorders in primary care. Implications for screening. Arch Fam Med 1995;4:857-861. 
  4. 4. Hasin DS, Goodwin RD, Stinson FS, Grant BF. Epidemiology of major depressive disorder: Results from the national epidemiologic survey on alcoholism and related conditions. Arch Gen Psychiatry 2005; 62:1097-1106. 
  5. 5. World Health Organization. The world health report 2001: Mental health- new understanding, new hope. Geneva: World Health Organization; 2001. 
  6. 6. Kessler RC, Chiu WT, Jin R, Ruscio AM, Shear K, Walters EE. The epidemiology of panic attacks, panic disorder, and agoraphobia in the national comorbidity survey replication. Arch Gen Psychiatry 2006; 63:415-424. 
  7. 7. Leckman JF, Weissman MM, Merikangas KR, Pauls DL, Prusoff BA. Panic disorder and major depression. Increased risk of depression, alcoholism, panic, and phobic disorders in families of depressed probands with panic disorder. Arch Gen Psychiatry 1983;40:1055-1060. 
  8. 8. Biederman J, Rosenbaum JF, Bolduc EA, Faraone SV, Hirshfeld DR. A high risk study of young children of parents with panic disorder and agoraphobia with and without comorbid major depression. Psychiatry Res 1991;37:333-348. 
  9. 9. Weissman MM, Wickramaratne P, Adams PB, Lish JD, Horwath E, Charney D, et al. The relationship between panic disorder and major depression. A new family study. Arch Gen Psychiatry 1993;50:767-780. 
  10. 10. Roy-Byrne PP, Stang P, Wittchen HU, Ustun B, Walters EE, Kessler RC. Lifetime panic-depression comorbidity in the national comorbidity survey. Association with symptoms, impairment, course and help-seeking. Br J Psychiatry 2000;176:229-235. 
  11. 11. Vollrath M, Angst J. Outcome of panic and depression in a seven-year follow-up: Results of the zurich study. Acta Psychiatr Scand 1989;80: 591-596. 
  12. 12. Cassano GB, Michelini S, Shear MK, Coli E, Maser JD, Frank E. The panic-agoraphobic spectrum: A descriptive approach to the assessment and treatment of subtle symptoms. Am J Psychiatry 1997;154: 27-38. 
  13. 13. Choi YH, Kim W, Kim MS, Yoon HY, Choi SM, Woo JM. Clinical characteristics and heart rate variability in patients with comorbid panic disorder and major depressive disorder. Sleep Med Psychophysiol 2005;12:50-57. 
  14. 14. Dube S, Jones DA, Bell J, Davies A, Ross E, Sitaram N. Interface of panic and depression: Clinical and sleep eeg correlates. Psychiatry Res 1986;19:119-133. 
  15. 15. Ahn JY, Oh JM, Kim SJ, Lee S-H, Park S, Hong JP. Clinical characteristics in panic disorder patients with or without depressive disorders. J of Kor Soc for Dep and Bip Disorders 2008;6:109-113. 
  16. 16. Meuret AE, White KS, Ritz T, Roth WT, Hofmann SG, Brown TA. Panic attack symptom dimensions and their relationship to illness characteristics in panic disorder. J Psychiatr Res 2006;40:520-527. 
  17. 17. Yaseen ZS, Chartrand H, Mojtabai R, Bolton J, Galynker, II. Fear of dying in panic attacks predicts suicide attempt in comorbid depressive illness: Prospective evidence from the national epidemiological survey on alcohol and related conditions. Depress Anxiety 2013;30: 930-939. 
  18. 18. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960;23:56-62. 
  19. 19. Hamilton M. Hamilton anxiety scale;1959. 
  20. 20. Kim JB. Development of the korean version of the panic disorder severity scale. Korean J Psychopathol 2001;10:140-151. 
  21. 21. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, et al. The mini-international neuropsychiatric interview (m.I.N. I.): The development and validation of a structured diagnostic psychiatric interview for dsm-iv and icd-10. J Clin Psychiatry 1998;59 Suppl 20:22-33; quiz 34-57. 
  22. 22. Yoo SW, Kim YS, Noh JS, Oh KS, Kim CH, Namkoong K, et al. Validity of korean version of the mini international neuropsychiatric interview. Anxiety Mood 2006;2:50-55. 
  23. 23. Maser JD, Cloninger CR. Comorbidity of anxiety and mood disorders: Introduction and overview. In: Maser JD, Cloninger CR, editors. Comorbidity of anxiety and mood disorders. Washington DC: American Psychiatric Press;1990. p.1-12. 
  24. 24. Breier A, Charney DS, Heninger GR. Major depression in patients with agoraphobia and panic disorder. Arch Gen Psychiatry 1984;41: 1129-1135. 
  25. 25. Dealy RS, Ishiki DM, Avery DH, Wilson LG, Dunner DL. Secondary depression in anxiety disorders. Compr Psychiatry 1981;22:612- 618. 
  26. 26. "Facts about panic disorder". National institute of mental health. Archived from the original on 2006-09-07. Retrieved 2006-09-30. 
  27. 27. Kuehner C. Gender differences in unipolar depression: An update of epidemiological findings and possible explanations. Acta Psychiatr Scand 2003;108:163-174. 
  28. 28. Bruch MA, Cheek JM. Developmental factors in childhood and adolescent shyness. In: Heimberg RG, Liebowitz MR, Hope DA, Schneier FR, editors. Social phobia: Diagnosis, assessment, and treatment. New York: Guilford Press;1995. p.163-182. 
  29. 29. Rapee RM. Descriptive psychopathology of social phobia. In: Heimberg RG, Liebowitz MR, Hope DA, Schneier FR, editors. Social phobia: Diagnosis, assessment, and treatment. New York: Guilford Press; 1995. p.41-66. 
  30. 30. Kikuchi M, Komuro R, Oka H, Kidani T, Hanaoka A, Koshino Y. Panic disorder with and without agoraphobia: Comorbidity within a half-year of the onset of panic disorder. Psychiatry Clin Neurosci 2005;59:639-643. 
  31. 31. Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR, et al. The epidemiology of major depressive disorder: Results from the national comorbidity survey replication (ncs-r). JAMA 2003;289: 3095-3105. 
  32. 32. Arnstein P, Caudill M, Mandle CL, Norris A, Beasley R. Self efficacy as a mediator of the relationship between pain intensity, disability and depression in chronic pain patients. Pain 1999;80:483-491. 
  33. 33. Berendsen HH. The role of serotonin in hot flushes. Maturitas 2000; 36:155-164. 
  34. 34. Plouffe L Jr, Trott EA, Largoza M, Hansen KA. An open trial of sertraline for menopausal hot flushes: Potential involvement of serotonin in vasomotor instability. Del Med J 1997;69:481-482. 
  35. 35. Roth AJ, Scher HI. Sertraline relieves hot flashes secondary to medical castration as treatment of advanced prostate cancer. Psychooncology 1998;7:129-132. 
  36. 36. Loprinzi CL, Pisansky TM, Fonseca R, Sloan JA, Zahasky KM, Quella SK, et al. Pilot evaluation of venlafaxine hydrochloride for the therapy of hot flashes in cancer survivors. J Clin Oncol 1998;16:2377-2381. 
  37. 37. Murphy DL, Mueller EA, Hill JL, Tolliver TJ, Jacobsen FM. Comparative anxiogenic, neuroendocrine, and other physiologic effects of m-chlorophenylpiperazine given intravenously or orally to healthy volunteers. Psychopharmacology (Berl) 1989;98:275-282. 

문의하기 

궁금한 사항이나 기타 의견이 있으시면 남겨주세요.

Q&A 등록

원문보기

원문 PDF 다운로드

  • ScienceON :
  • KCI :

원문 URL 링크

원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다. (원문복사서비스 안내 바로 가기)

DOI 인용 스타일

"" 핵심어 질의응답