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NTIS 바로가기JKSDH : Journal of Korean Society of Dental Hygiene = 한국치위생학회지, v.16 no.2, 2016년, pp.155 - 163
The purpose of the review article is to investigate the influence of periodontal diseases on preterm birth(PTB) and low birth weight(LBW). PTB and LBW are the main risk factors of infant mortality and a major public health problem. PTB is defined as delivery at less than 37 weeks and LBW is less tha...
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핵심어 | 질문 | 논문에서 추출한 답변 |
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임신기는 어떠한 특징을 가지는가? | 임신기는 체내 호르몬 변화와 함께 신체적인 변화가 급격하게 일어나는 시기이다. 더불어 구강 내 치주조직에서도 많은 변화가 나타나는데, 가임기 여성이 임신을 하면 이로 인하여 임신성 치은염이 발생되는 경우가 35-100%에 이르며, 이 중에서 약 10%는 화농성 육아종으로 악화될 수 있다[1]. | |
임신성 치은염이 발생하는 이유는? | 더불어 구강 내 치주조직에서도 많은 변화가 나타나는데, 가임기 여성이 임신을 하면 이로 인하여 임신성 치은염이 발생되는 경우가 35-100%에 이르며, 이 중에서 약 10%는 화농성 육아종으로 악화될 수 있다[1]. 이러한 치주조직의 변화가 나타나는 원인으로는 임신으로 인하여 에스트로겐과 프로게스테론의 농도가 증가하고, 이와 함께 혈관확장, 혈소판응집억제, 염증유기 등의 염증발현에 중요한 역할을 하는 지방산인 프로스타글란딘의 합성이 치은열구 내 조직에서 주로 이루어져, 치은출혈, 치은연하 세균총의 변화를 일으키기 때문이다[2,3]. 또한 임신기는 염증에 대한 감수성이 증가하므로, 치주조직 감염에 대한 위험성도 증가할 수 있는 시기이다[4]. | |
조산 혹은 저체중 영아의 위험성은? | 조산 및 저체중아 출산은 영유아 사망 등의 주요 원인으로 공중보건의 대표적인 문제 중 하나이며[5], 저출산으로 인한 인구 구성의 급격한 변화를 겪고 있는 우리나라에서는 더욱 심각한 문제라 할 수 있다. 조산 및 저체중아 출산율은 약 10% 내외로 나타나며, 조산 혹은 저체중 영아의 경우, 호흡기계 질환, 심혈관계 이상, 간질, 심각한 학습 장애의 위험이 높은 것으로 알려져 있다[5]. 이러한 조산 및 저체중아 출산의 위험요인으로는 현재까지 흡연, 음주, 약물남용, 산전관리의 소홀, 영양 및 호르몬 문제 등으로 보고된바 있으나, 감염이 가장 주요한 원인으로 꼽히고 있어, 구강 내의 만성염증질환인 치주염이 조산 및 저체중아 출산에 영향을 미칠 수 있다는 가설이 제기되어 1996년에 치주염과 조산 및 저체중아 출산의 연관성을 확인하기 위하여 역학조사연구가 수행되기 시작하였다. |
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