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NTIS 바로가기Environmental health and toxicology : Eht, v.31, 2016년, pp.13.1 - 13.4
Park, Kwangsik (College of Pharmacy, Dongduk Women's University)
An analysis of patients and fatalities due to exposure to polyhexamethylene guanidine (PHMG) shows that PHMG causes mainly lung diseases such as pulmonary fibrosis. However, no research on the other organs has been conducted on this matter yet. So, an in-depth discussion on toxicological techniques ...
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1 Asian Citizen’s Center for Environment and Health Population survey of humidifier disinfectant use 2016 [cited 2016 Feb 25]. Available from: http://eco-health.org/bbs/board.php?bo_table=sub02_04&wr_id=160 (Korean)
3 Ostapenko YN Brusin KM Zobnin YV Shchupak AY Vishnevetskiy MK Sentsov VG Acute cholestatic liver injury caused by polyhexamethyleneguanidine hydrochloride admixed to ethyl alcohol Clin Toxicol (Phila) 2011 49 6 471 477 21761961
4 Asiedu-Gyekye IJ Mahmood SA Awortwe C Nyarko AK A preliminary safety evaluation of polyhexamethylene guanidine hydrochloride Int J Toxicol 2014 33 6 523 531 25359731
5 Kim HR Lee K Park CW Song JA Shin da Y Park YJ Polyhexamethylene guanidine phosphate aerosol particles induce pulmonary inflammatory and fibrotic responses Arch Toxicol 2016 90 3 617 632 25716161
6 Kwon do Y Kim HM Kim E Lim YM Kim P Choi K Acute pulmonary toxicity and inflammation induced by combined exposure to didecyldimethylammonium chloride and ethylene glycol in rats J Toxicol Sci 2016 41 1 17 24 26763389
7 Ohnuma-Koyama A Yoshida T Tajima-Horiuchi H Takahashi N Yamaguchi S Ohtsuka R Didecyldimethylammonium chloride induces pulmonary fibrosis in association with TGF-β signaling in mice Exp Toxicol Pathol 2013 65 7-8 1003 1009 23537712
8 Ohnuma A Yoshida T Tajima H Fukuyama T Hayashi K Yamaguchi S Didecyldimethylammonium chloride induces pulmonary inflammation and fibrosis in mice Exp Toxicol Pathol 2010 62 6 643 651 19762220
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