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NTIS 바로가기Korean journal of clinical laboratory science : KJCLS = 대한임상검사과학회지, v.49 no.4, 2017년, pp.470 - 476
김진목 (성균관대학교 삼성창원병원 병리과) , 이현욱 (성균관대학교 삼성창원병원 병리과)
Changes in the mammalian target of the rapamycin (mTOR) signaling proteins have been observed in many types of cancer. Accordingly, these proteins have recently become an exciting new target for molecular therapeutics. This study examined the expression of an activated mTOR signaling protein in pati...
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Brown EJ, Albers MW, Shin TB, Ichikawa K, Keith CT, Lane WS, et al. "A mammalian protein targeted by G 1-arresting rapamycin-receptor complex". Nature. 1994;369(6483):756-758.
Kim, DH, Sarbassov DD, Ali, SM, King JE, Latek RR, Erdjument-Bromage H, et al. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell. 2002;110(2):163-176.
Hermsen M, Postma C, Baak J, Weiss M, Rapallo A, Sciutto A, et al. Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability. Gastroenterology. 2002;123(4):1109-1119.
Jackman RJ, Mayo CW. The adenoma-carcinoma sequence in cancer of the colon. Surg Gynecol Obstet. 1951;93(3):327-330.
Nagel R, le Sage C, Diosdado B, van der Waal M, Oude Vrielink JAF, Bolijn A, et al. Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer. Cancer Res. 2008;68(14):5795-5802.
Toll AD, Fabius D, Hyslop T, Pequignot E, DiMarino AJ, Infantolino A, et al. Prognostic significance of high-grade dysplasia in colorectal adenomas. Colorectal Dis. 2011;13(4): 370-373.
Brenner H, Chang-Claude J, Seiler CM, Rickert A, Hoffmeister M. Protection from colorectal cancer after colonoscopy. Ann Intern Med. 2011;154(1):22-30.
Mamane Y, Petroulakis E, LeBacquer O, Sonenberg N. mTOR, translation initiation and cancer. Oncogene. 2006;25(48): 6416-6422.
Tee AR, Blenis J. mTOR, translational control and human disease. Semin Cell Dev Biol. 2005;16(1):29-37.
Noh WC, Kim YH, Kim MS, Koh JS, Kim HA, Moon NM, et al. Activation of the mTOR signaling pathway in breast cancer and its correlation with the clinicopathologic variables. Breast Cancer Res Treat. 2008;1109(3):477-483
No JH, Jeon YT, Park IA, Kim YB, Kim JW, Park NH, et al. Activation of mTOR signaling pathway associated with adverse prognostic factors of epithelial ovarian cancer. Gynecol Oncol. 2011;121(1):8-12.
Faivre S, Kroemer G, Raymond E. "Current development of mTOR inhibitors as anticancer agents". Nat Rev Drug Discov. 2006;5(8):671-88.
Fingar DC, Salama S, Tsou C, Harlow E, Blenis J. Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. Genes Dev. 2002;16(12):1472-1487.
Brown EJ, Beal PA, Keith CT, Chen J, Shin, TB, Schreiber, SL. Control of p70 s6 kinase by kinase activity of FRAP in vivo. Nature. 1995;377(6548):441-446.
Burnett PE, Barrow RK, Cohen NA, Snyder SH, Sabatini DM. RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. Proc Natl Acad Sci. 1998;95(4):1432-1437
Gingras AC, Gygi SP, Raught B, Polakiewicz RD, Abraham RT, Hoekstra, M.F. et al. Regulation of 4E-BP1 phosphorylation: A novel two step mechanism. Genes Dev. 1999;13:1422-1437.
Inoki K, Ouyang H, Li Y, Guan KL. Signaling by target of rapamycin proteins in cell growth control. Micro Mol Biol Rev. 2005;69(1):79-100.
Lazaris-Karatzas A, Montine KS, Sonenberg N. Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA cap. Nature. 1990;345(6275):544-7.
Graff JR, Boghaert ER, DeBenedetti A, Tudor DM, Zimmer SG. Reduction of translation initiation factor 4E reduces tumor growth, invasion and metastasis of ras transformed cloned rat embryo fibroblast. Int J Cancer. 1995;60(17):255-63.
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