[논문]비스페놀류의 사용 현황과 위해성: 소고

송창엽; 김웅; 계명찬

doi:10.11626/kjeb.2017.35.4.581

비스페놀류의 사용 현황과 위해성: 소고
Current State of Use and the Risks of Bisphenols: A Minireview 원문보기

환경생물 = Korean journal of environmental biology, v.35 no.4, 2017년, pp.581 - 594

송창엽 (한양대학교 생명과학과 자연과학연구소) , 김웅 (한양대학교 생명과학과 자연과학연구소) , 계명찬 (한양대학교 생명과학과 자연과학연구소)

초록
AI-Helper

비스페놀 A는 플라스틱과 에폭시 레진에 사용되는 대표적인 내분비계 교란물질이다. BPA가 함유된 플라스틱은 물병, 식품용기, CD, DVD, 그리고 건설현장에서 사용되는 건축자재 등에 사용되고 있으며, BPA가 함유된 에폭시 레진은 상수도관 내의 코팅제, 식품용 캔 그리고 영수증용 감열지 등에 사용되고 있다. BPA의 에스트로젠 유사효과와 다른 유해 영향이 많이 보고되고 있기 때문에 이미 많은 나라에서 BPA가 규제되고 있으며, BPA의 대체재를 만들기 위해 노력 중에 있다. 비스페놀 S와 비스페놀 F가 BPA의 대체재로 사용되고 있으며, 최근에 BPS와 BPF가 함유된 제품들이 광범위하게 소비되고 있다. 하지만, BPA와 비슷한 화학구조 때문에 이 대체재들 또한 BPA처럼 내분비계의 교란을 일으키며 이 대체재들의 유해 영향도 이미 많은 연구들을 통해 보고되고 있는 실정이다. 본 소고에서 비스페놀류의 유해 영향과 규제 현황을 기술하고자 한다.

Abstract ▼ AI-Helper

Bisphenol A(BPA), known as a typical endocrine disruptor, has been used commercially and widely for plastics and epoxy resins. BPA-based plastic is used extensively for the production of water bottles, food containers, CDs, DVDs, and panels that can be applied in construction. Epoxy resins containing BPA are used for coatings on the insides of water pipes, food cans, and thermal papers that are used in sales receipts. As its estrogenic effects and other adverse health effects have published, BPA has been regulated in many countries, and there have been efforts made to replace BPA. Other bisphenols substitutes such as bisphenol S(BPS) and bisphenol F(BPF) have been used. Currently, BPS- and BPF-based products labeled BPA-free products have been widely consumed. Because of structural similarities with BPA, however, these alternatives also show endocrine disruption effects like BPA, and many studies on adverse health effects of these alternatives are being reported. In this review, we describe the adverse health effects of bisphenols and the current status of regulation.

주제어

AI 본문요약
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문제 정의

하지만, BPA와 비슷한 화학구조 때문에 이 대체재들 또한 BPA처럼 내분비계의 교란을 일으키며 이 대체재들의 유해 영향도 이미 많은 연구들을 통해 보고되고 있는 실정이다. 본 소고에서 비스페놀류의 유해 영향과 규제 현황을 기술하고자 한다.

제안 방법

이를 반증하듯 국내의 관공서, 은행, 유통업체에서 사용되는 감열지에서 BPA가 검출되고 있다(서울시 공공기관의 감열지 영수증 비스페놀 화합물 조사결과, KWEN,2016). EU, 미국, 일본 등 주요 국가와 한국의 비스페놀류 규제 현황을 표로 정리하였다(Table 2).

성능/효과

2017). 결론적으로 BPF 역시 BPA 만큼 유해한 내분비계 교란물질이라 할 수 있다(Table 1).
2017). 이러한 결과들을 종합하면 BPS도 BPA와 다를 바 없는 내분비계 장애물질이라 할 수 있다(Table 1). BPS는 현재 BPA의 가장 대표적인 대체재이며, 다양한 유해 영향 가능성이 보고되었으나 현재 구체적인 규제는 없고 국제화학사무국(ChemSec)에서 제공하는 SIN(Substitute It Now!) list에 법률로 규제가 요구되는 물질로 등재되어 있으며(Table 2), 유럽위원회(EC)에서고시한 BPA의 신규 규제 내용에서 BPS에 대한 감시가 필요하다고 보고되었다(EC 2016).
국내에서는 캔 코팅에 BPF 사용이 미미하지만 BPF가 코팅제로 사용된 주철관을 상수도관으로 사용하고 있다(Moon 2014; Office of Water Works 2014). 한국, 중국, 일본, 인도 4개국의 14개 지역의 취수장 용수에서 BPA, BPF, BPS가 검출되었으며, 인도를 제외한 3개국에서 BPF의 농도가 가장 높았다. 특히, 한강 시료의 경우 BPA 농도가 평균 144 ng L^-1인 반면 BPF는 555 ng L^-1로 BPA보다 4배 높았다.

후속연구

따라서 BPF가 RXRα 신호전달을 교란하여 발생에 영향을 미칠 가능성이 있으므로 좀 더 심도 깊은 연구가 필요할 것이다.
2012). 또한 대체 물질들의 도입에 앞서 그 안전성에 대한 심도 있고 구체적인 평가가 이뤄져야 할 것이다.

질의응답

핵심어	질문	논문에서 추출한 답변
	비스페놀 A는 무엇인가?	비스페놀 A는 플라스틱과 에폭시 레진에 사용되는 대표적인 내분비계 교란물질이다. BPA가 함유된 플라스틱은 물병, 식품용기, CD, DVD, 그리고 건설현장에서 사용되는 건축자재 등에 사용되고 있으며, BPA가 함유된 에폭시 레진은 상수도관 내의 코팅제, 식품용 캔 그리고 영수증용 감열지 등에 사용되고 있다.
	BPA 대체제인 비스페놀 S와 비스페놀 F의 한계점은?	비스페놀 S와 비스페놀 F가 BPA의 대체재로 사용되고 있으며, 최근에 BPS와 BPF가 함유된 제품들이 광범위하게 소비되고 있다. 하지만, BPA와 비슷한 화학구조 때문에 이 대체재들 또한 BPA처럼 내분비계의 교란을 일으키며 이 대체재들의 유해 영향도 이미 많은 연구들을 통해 보고되고 있는 실정이다. 본 소고에서 비스페놀류의 유해 영향과 규제 현황을 기술하고자 한다.
	BPA가 사용되는 곳은 어디인가?	비스페놀 A는 플라스틱과 에폭시 레진에 사용되는 대표적인 내분비계 교란물질이다. BPA가 함유된 플라스틱은 물병, 식품용기, CD, DVD, 그리고 건설현장에서 사용되는 건축자재 등에 사용되고 있으며, BPA가 함유된 에폭시 레진은 상수도관 내의 코팅제, 식품용 캔 그리고 영수증용 감열지 등에 사용되고 있다. BPA의 에스트로젠 유사효과와 다른 유해 영향이 많이 보고되고 있기 때문에 이미 많은 나라에서 BPA가 규제되고 있으며, BPA의 대체재를 만들기 위해 노력 중에 있다.

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