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NTIS 바로가기한국식품과학회지 = Korean journal of food science and technology, v.49 no.2, 2017년, pp.123 - 131
강지현 (충북대학교 식품생명공학과) , 심혜미 (충북대학교 식품생명공학과) , 김광엽 (충북대학교 식품생명공학과)
Norovirus causes frequent epidemic viral gastroenteritis in Korea. The team for the control of noroviral foodborne outbreaks (NOROTECL) executed a project to trace the cause of norovirus contamination in agricultural products and environmental samples to reduce norovirus outbreaks in Korea. Between ...
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핵심어 | 질문 | 논문에서 추출한 답변 |
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노로바이러스란 무엇인가? | 노로바이러스는 칼리시바이러스과(Caliciviridae)에 속하며 약 7.7 kb의 외피가 없는 외가닥(single stranded) RNA 바이러스이며 전 세계적으로 가장 많은 장염을 일으키는 병원성 미생물로 비세균성 장염의 약 90% 이상의 발병원인으로도 알려져 있다. 주 증상으로는 오심, 구토, 설사, 복통을 유발하나 대부분의 경우 증상은 경미하고 1-2일 지나면 자연 회복되며, 잠복기는 24-48시간이다(1-6). | |
노로바이러스 감염의 주 증상은 무엇인가? | 7 kb의 외피가 없는 외가닥(single stranded) RNA 바이러스이며 전 세계적으로 가장 많은 장염을 일으키는 병원성 미생물로 비세균성 장염의 약 90% 이상의 발병원인으로도 알려져 있다. 주 증상으로는 오심, 구토, 설사, 복통을 유발하나 대부분의 경우 증상은 경미하고 1-2일 지나면 자연 회복되며, 잠복기는 24-48시간이다(1-6). | |
노로바이러스는 어떻게 구분되는가? | 노로바이러스는 유전학적 면역학적으로 매우 다양한 바이러스로 알려져 있다. 노로바이러스는 크게 5가지의 genogroup (GI-GV)으로 구분된다(7). 이중 GI, GII, GIV 유전자형은 인간에게 급성장염을 일으키는 병원성 바이러스이며 분자생물학적, 역학적, 계통학적으로 매우 상의하여 유전자 염기서열에 따라 유전자형 GI은 14 아형, 유전자형 GII은 17 아형으로 모두 31가지의 유전자 타입(Genotype)으로 분류 되고 있다(8-12). |
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Shin SB, Oh EG, Yu HS, Lee HJ, Kim JH, Park KBW, Kwon JY, Yun HD, Son KT. Inactivation of a norovirus surrogate (Feline calicivirus) during the ripening of oyster kimch. Korean J. Fish Aquat. Sci. 43: 415-420 (2010)
Kim KY. Research on the contamination levels of norovirus in food catering facilities. National Institute of Food and Drug Safety Evaluation, Osong, Korea. pp. 1-98 (2009)
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Kim BJ. Correlation between norovirus detection and indicator organisms presence in agricultural produce, growing soil, feces, agricultural water, and river water. MS thesis, University of Dongguk, Gyeongju, Korea (2015)
Choi WS. Development of protocol for the detection of foodborne virus in food. National Institute of Food and Drug Safety Evaluation, Osong, Korea. pp. 1-90 (2004)
Lu QB, Huang DD, Zhao J, Wang HY, Zhang XA, Xu HM, Qu F, Liu W, Cao WC. An increasing prevalence of recombinant GII norovirus in pediatric patients with diarrhea during 2010-2013 in China. Infect. Genet. Evol. 31: 48-52 (2015)
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Hedlund KO, Rubilar-Abreu E, Svensson L. Epidemiology of calicivirus infections in Sweden, 1994-1998. J. Infect. Dis. 181: 275-280 (2000)
Ho ECM, Cheng PKC, Lau AWL, Wong AH, Lim WWL. Atypical norovirus epidemic in Hong Kong during summer of 2006 caused by a new genogroup II/4 variant. J. Clin. Microbiol. 45: 2205-2011 (2007)
Oh SA, Park SH, Ham HJ, Seung HJ, Jang JI, Suh SW, Jo SJ, Choi SM, Jeong HS. Molecular characterization of norovirus and rotavirus in outbreak of acute gastroenteritis in Seoul. J. Bacteriol. 43: 307-316 (2013)
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Hedlund KO, Rubilar-Abreu E, Svensson L. Epidemiology of calicivirus infections in Sweden, 1994-1998. J. Infect. Dis. 181:275-280 (2000)
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