선택한 단어 수는 입니다.
최소 단어 이상 선택하여야 합니다.
최소 단어 이상 선택하여야 합니다.
선택한 단어 수는 30입니다.
최대 10 단어까지만 선택 가능합니다.
최대 10 단어까지만 선택 가능합니다.
제안 방법
- Statistical analysis was performed using analysis of variance followed by Turkey's post-hoc tests.
- Therefore, the effects of DF on visceral obesity and visceral obesity-induced hepatic inflammation and fibrosis were examined in high fat diet (HFD)-induced obese C57BL /6J mice and HepG2 cells, and investigated the histological and molecular events involved in this process. The present results demonstrate that DF inhibits visceral obesity, infiltration of inflammatory cells into the liver, and hepatic collagen accumulation and that this process may be mediated by regulating the hepatic expression of inflammation and fibrosis genes.
- , 2015). To determine the effect of DF on visceral obesity, HFD-fed obese mice were treated with DF-FW, DF-GA30, and DF-GA70 for 8 weeks. HFD-fed control mice had much higher visceral fat mass and visceral adipocyte size compared with LFD-fed normal mice.
- To evaluate whether the inhibitory effects of DF on hepatic fibrosis in obese mice were associated with alterations of the expression of fibrosis genes such as TGFβ1, α smooth muscle actin (α-SMA), and collagen α1.
대상 데이터
- DF was prepared from food-grade extracts of the three medicinal herbs (40% Ephedra intermedia, 40% Lithospermum erythrorhizon, and 20% Rheum palmatum; ex pressed as % dry weight of DF) (Hwalim, Busan, Korea). The proportions used in this study are same as those used to treat patients in local clinics of Korea.
- The genes of interest were amplified from the synthesized cDNA using AccuPower® GreenStarTM qPCR PreMix (Bioneer, Deajeon, Korea) on an ExcyclerTM 96 Real Time Quantitative Thermal Block machine (Bioneer).
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