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NTIS 바로가기한국임상약학회지 = Korean journal of clinical pharmacy, v.27 no.3, 2017년, pp.136 - 142
Background: Dementia is one of important social and economic healthcare issues in the aging age. Therefore, it signifies to analyze the relationship between chronic disease or cardiovascular drug use and the incidence of dementia to establish a basis for increasing or preventing the risk of dementia...
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핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
치매의 위험성이 더 높은 성별은? | 환자 요인과 알츠하이머에서 환자 요인의 상관성은 모든 치매의 종류에서 남성보다 여성에서 위험도가 증가하는 것으로 분석되었고, 다른 치매와 비교하여 알츠하이머의 경우 OR 값이 1.987 (95% CI;1. | |
치매의 유병률과 연령은 상관이 있는가? | 522, P<0.001)로 나타나, 치매의 유병률과 연령의 상관관계는 매우 높으며 그 위험도 증가폭도 크게 분석되었다. 의료급 여종과 치매의 상관성에 대해서는 질환마다 상이하게 나타났다. | |
고혈압 환자와 이상 지질혈증 환자에서 유병률이 낮게 나타난 이유는? | 치매와 동반질환의 상관성을 분석하였을 때, 고혈압 환자와 이상 지질혈증 환자에서 알츠하이머 유병률이 더 낮게 나타났다. 이는 고혈압 환자나 이상 지질혈증 환자에서 알츠하이머의 위험이 낮아진다고 해석하기보다는 기존의 연구결과에 비추어 볼 때, ACEI 또는 ARB, CCB 등의 약물의 사용이나 statin 등의 약물 사용이 알츠하이머의 유병률을 감소시킨다는 결과로 해석하는 것이 바람직할 것이다. 또한 허혈성 뇌졸중이 치매의 높은 위험인자로 보고된 그동안의 연구결과와 비슷한 결과로 제시되었다. |
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