관리용액 점안이 소프트콘택트렌즈를 착용한 건성안의 눈물막 안정성에 미치는 영향 The Effects of Lens Care Solution Instillation on Tear Film Stability of Soft Contact Lens Wearers with Dry Eyes원문보기
목적: 본 연구에서는 렌즈 관리용액이 점안에 사용되는 실태와 관리용액 점안에 대한 인식을 조사하고 관리용액의 점안이 소프트콘택트렌즈를 착용한 건성안의 눈물막 안정성 및 자각증상에 미치는 영향을 알아보고자 하였다. 방법: 렌즈 관련 전문지식이 없는 렌즈 착용자를 대상으로 온라인 설문조사를 실시하여 렌즈 관리용액의 점안제로서의 사용 실태와 점안에 대한 인식을 조사하였다. 콘택트렌즈를 착용한 건성안에 인공눈물과 렌즈 관리용액(2종의 다목적용액과 1종의 습윤액)을 점안한 후 NIBUT, 순목 횟수를 측정하고 설문조사를 통해 점안에 따른 자각증상을 평가하였다. 결과: 적지 않은 렌즈 착용자가 관리용액을 본래의 용도가 아닌 점안에 사용하거나 관리용액 점안에 대해 긍정적인 인식을 가지고 있었으며 많은 수의 응답자가 관리용액의 정확한 사용법을 모른다고 답하였다. 인공눈물 및 렌즈 관리용액 점안 후 NIBUT는 점안 초기에는 모두 증가하였으나 렌즈 관리용액은 점안 15 ~ 20분 후부터 NIBUT가 감소되었다. 4종의 용액 모두 점안 후 순목 횟수의 변화는 미미했다. 인공눈물 점안 후에는 대부분의 자각증상은 개선되었지만 2종의 다목적용액을 점안 후에는 대부분의 증상이 악화되었다. 결론: 관리용액은 인공눈물에 비해 눈물막 안정성 유지 효과가 떨어지고 자각증상의 악화를 유발하므로 건성안에는 인공눈물의 점안이 가장 효과적이고 안전하며 렌즈 관리용액의 올바른 사용법에 대한 교육이 실시될 필요가 있다.
목적: 본 연구에서는 렌즈 관리용액이 점안에 사용되는 실태와 관리용액 점안에 대한 인식을 조사하고 관리용액의 점안이 소프트콘택트렌즈를 착용한 건성안의 눈물막 안정성 및 자각증상에 미치는 영향을 알아보고자 하였다. 방법: 렌즈 관련 전문지식이 없는 렌즈 착용자를 대상으로 온라인 설문조사를 실시하여 렌즈 관리용액의 점안제로서의 사용 실태와 점안에 대한 인식을 조사하였다. 콘택트렌즈를 착용한 건성안에 인공눈물과 렌즈 관리용액(2종의 다목적용액과 1종의 습윤액)을 점안한 후 NIBUT, 순목 횟수를 측정하고 설문조사를 통해 점안에 따른 자각증상을 평가하였다. 결과: 적지 않은 렌즈 착용자가 관리용액을 본래의 용도가 아닌 점안에 사용하거나 관리용액 점안에 대해 긍정적인 인식을 가지고 있었으며 많은 수의 응답자가 관리용액의 정확한 사용법을 모른다고 답하였다. 인공눈물 및 렌즈 관리용액 점안 후 NIBUT는 점안 초기에는 모두 증가하였으나 렌즈 관리용액은 점안 15 ~ 20분 후부터 NIBUT가 감소되었다. 4종의 용액 모두 점안 후 순목 횟수의 변화는 미미했다. 인공눈물 점안 후에는 대부분의 자각증상은 개선되었지만 2종의 다목적용액을 점안 후에는 대부분의 증상이 악화되었다. 결론: 관리용액은 인공눈물에 비해 눈물막 안정성 유지 효과가 떨어지고 자각증상의 악화를 유발하므로 건성안에는 인공눈물의 점안이 가장 효과적이고 안전하며 렌즈 관리용액의 올바른 사용법에 대한 교육이 실시될 필요가 있다.
Purpose: This study investigated the usage of lens care solution as an eye drop, the perception of lens care solution instillation, and the effects of lens care solution instillation on tear film stability and subjective symptoms of soft contact lens wearers with dry eyes. Methods: To investigate th...
Purpose: This study investigated the usage of lens care solution as an eye drop, the perception of lens care solution instillation, and the effects of lens care solution instillation on tear film stability and subjective symptoms of soft contact lens wearers with dry eyes. Methods: To investigate the actual usage of lens care solution as an eye drop and the perception of lens care solution instillation, an online survey was conducted on lens wearers who had no expert lens knowledge. Artificial tear and lens care solutions (2 multipurpose solutions and 1 wetting solution) were applied to contact lens wearers with dry eyes and their NIBUT and blink rate were measured. A survey was conducted to investigate the subjective symptoms following instillation. Results: More than a few lens wearers have used lens care solution as an eye drop, which isn't its original use, or had a positive perception of lens care solution instillation. A large number of respondents didn't know the exact direction for use of the lens care solution. NIBUT increased immediately after the instillation of artificial tear and lens care solutions yet decreased after 15 ~ 20 minutes following lens care solution instillation. All four solutions showed little effect on the change of blink rate after instillation. Although most subjective symptoms improved after artificial tear instillation, they worsened after instillation of multipurpose solutions. Conclusions: Lens care solutions are less effective in maintaining tear film stability than artificial tears and exacerbate subjective symptoms. Therefore, artificial tear instillation is the most effective and safe for dry eyes. In addition, lens wearers need to be educated on proper use of lens care solutions.
Purpose: This study investigated the usage of lens care solution as an eye drop, the perception of lens care solution instillation, and the effects of lens care solution instillation on tear film stability and subjective symptoms of soft contact lens wearers with dry eyes. Methods: To investigate the actual usage of lens care solution as an eye drop and the perception of lens care solution instillation, an online survey was conducted on lens wearers who had no expert lens knowledge. Artificial tear and lens care solutions (2 multipurpose solutions and 1 wetting solution) were applied to contact lens wearers with dry eyes and their NIBUT and blink rate were measured. A survey was conducted to investigate the subjective symptoms following instillation. Results: More than a few lens wearers have used lens care solution as an eye drop, which isn't its original use, or had a positive perception of lens care solution instillation. A large number of respondents didn't know the exact direction for use of the lens care solution. NIBUT increased immediately after the instillation of artificial tear and lens care solutions yet decreased after 15 ~ 20 minutes following lens care solution instillation. All four solutions showed little effect on the change of blink rate after instillation. Although most subjective symptoms improved after artificial tear instillation, they worsened after instillation of multipurpose solutions. Conclusions: Lens care solutions are less effective in maintaining tear film stability than artificial tears and exacerbate subjective symptoms. Therefore, artificial tear instillation is the most effective and safe for dry eyes. In addition, lens wearers need to be educated on proper use of lens care solutions.
Jung DI, Lee HS, Kim SR, Park M. The difference of tear break-up time by the fitting states of soft contact lens in normal and dry eyes. J Korean Ophthalmic Opt Soc. 2010;15(4):339-346.
Seo SG. The effect of artificial tear application on central corneal thickness in dry eye. J Korean Ophthalmol Soc. 2009;50(10):1483-1488.
Shin HM, Park M. Kim SR. The effect of difference in main components of artificial tears on tear film stability of soft contact lenses wearers. J Korean Ophthalmic Opt Soc. 2016;21(4):351-360.
Kim SR, Lim JA, Jung JH, Byun HY, Park M. The effect of artificial tear components on tear film stability of dry eyes in the early stage of soft contact lenses wear. J Korean Ophthalmic Opt Soc. 2016;21(3):191-201.
Choi TH, Kim HM, Cha HW, Kim JC, Kim MS, Lee HB. Research on the current status of contact lenses in Korea. J Korean Ophthalmol Soc. 2004;45(11):1833-1841.
Choi JY, Song YY, Byun JC. The status of contact lens wearing, management and eye health awareness among female university students in Jeju area. J Korean Ophthalmic Opt Soc. 2016;21(3):203-214.
Kim NY, Lee KJ. Cytotoxicity of multipurpose contact lens solutions on the cultured corneal epithelial cells evaluated by image analysis. J Korean Ophthalmic Opt Soc. 2015;20(1):51-60.
Price R, Gustafson J, Greish K, Cappello J, McGill L, Ghandehari H. Comparison of silk-elastinlike protein polymer hydrogel and poloxamer in matrix-mediated gene delivery. Int J Pharm. 2012;427(1):97-104.
Neal JC, Stolnik S, Garnett MC, Davis SS, Illum L. Modification of the copolymers poloxamer 407 and poloxamine 908 can affect the physical and biological properties of surface modified nanospheres. Pharm Res. 1998;15(2):318-324.
Nayak VS, Tan Z, Ihnat PM, Russell RJ, Grace MJ. Evaporative light scattering detection based HPLC method for the determination of polysorbate 80 in therapeutic protein formulations. J Chromatogr Sci. 2012;50(1):21-25.
Al Khateb K, Ozhmukhametova EK, Mussin MN, Seilkhanov SK, Rakhypbekov TK, Lau WM et al. In situ gelling systems based on Pluronic F127/Pluronic F68 formulations for ocular drug delivery. Int J Pharm. 2016;502(1-2):70-79.
Zhao M, Campolmi N, Thuret G, Piselli S, Acquart S, Peoc'h M et al. Poloxamines for deswelling of organ-cultured corneas. Ophthalmic Res. 2012;48(3):124-133.
Ho L, Di Carlo S, Moran KL, Bantseev V, Sivak JG. Effect of age on ocular irritancy as measured with in vitro bovine lenses. Toxicol In Vitro. 2008;22(2):450-456.
Ayaki M, Iwasawa A. Cell viability of four corneoconjunctival cell lines exposed to five preservatives and a surfactant used for infection control in eyedrops. Biocontrol Sci. 2011;16(3):117-121.
AI-Helper
※ AI-Helper는 부적절한 답변을 할 수 있습니다.