[논문]비급성 요통에 대한 위수혈 자락관법의 효과 탐색: 예비 무작위 대조군 시험

김형석; 조재흥; 김고운; 정원석; 박재현; 신우철; 정석희

doi:10.18325/jkmr.2018.28.4.21

[국내논문] 비급성 요통에 대한 위수혈 자락관법의 효과 탐색: 예비 무작위 대조군 시험
An Investigation on the Effects of Wet Cupping on Wisu (BL21) for Non-acute Low Back Pain: A Pilot Randomized Controlled Trial 원문보기

Journal of Korean Medicine Rehabilitation : JKMR = 한방재활의학과학회지, v.28 no.4, 2018년, pp.21 - 32

김형석 (경희대학교 대학원 임상한의학교실) , 조재흥 (경희대학교 대학원 임상한의학교실) , 김고운 (경희대학교 대학원 임상한의학교실) , 정원석 (경희대학교 대학원 임상한의학교실) , 박재현 (경희대학교 대학원 임상한의학교실) , 신우철 (경희대학교 대학원 임상한의학교실) , 정석희 (경희대학교 대학원 임상한의학교실)

Abstract ▼ AI-Helper

Objectives This study was designed to investigate the effects of wet cupping on Wisu (BL12) in non-acute low back pain patients. Methods We recruited 30 participants for this study. Fifteen patients were randomly assigned to the Wisu (BL21) treatment group (WT group) and 15 were assigned to the non-acupoint treatment group (NT group). Both groups were treated with the pricking-cupping bloodletting method three times. Values at baseline and follow-up were analyzed by Wilcoxon signed rank test and the differences between the two groups were determined by Wilcoxon rank sum test. p-values less than 0.05 were considered significant. The primary outcome was the visual analogue scale (VAS), and secondary outcomes were the Oswestry disability index (ODI), Rolland-Morris disability questionnaire (RMDQ), Euroqol-5 dimension questionnaire (EQ-5D) and finger-to-ground distance (FTGD). These outcomes were measured on the day of first treatment before the procedure and on follow-up 7 days after the last treatment. Results Significant changes were identified in the VAS for pain and ODI in each group after wet cupping treatment on Wisu (p<0.05). However, no significant changes were found between groups. Meanwhile, RMDQ and EQ-5D were significantly decreased only in the NT group (p<0.05) without any differences between groups. FTGD was decreased in both groups, but not significantly. Conclusions Wet cupping with both Wisu treatment and non-acupoint had significant effects on non-acute low back pain, although there were no differences between the two groups. A large-scale study is needed to identify the effect of wet cupping on Wisu.

Keyword

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제안 방법

Furthermore, no studies have analyzed differences in the effects according to different treatment locations. In this study, wet cupping was performed for non-acute low back pain patients on either Wisu or a designated non-acupoint to compare the effect.
This study recruited participants who had non-acute low back pain and randomized them into either a Wisu treatment group (WT group) or non-acupoint treatment group (NT group). Wet cupping was conducted on the designated area according to groups and the degree of pain, physical function and quality of life were evaluated to see the feasibility of treating Wisu as a tr eatment point for low back pain.
VAS, Oswestry disability index (ODI), Roland-Morris disability questionnaire (RMDQ), Euroqol-5 dimensions questionnaire (EQ-5D), and finger-to-ground distance (FTGD) were measured by an evaluator on the first visit.
Wet cupping was repeated three times over an approximately 72-hour period. On follow-up, a week after the 3rd treatment, VAS, ODI, RMDQ, EQ-5D, and FTGD were evaluated. A 24-hour difference was allowable at each visit.
This study was designed to see if wet cupping on Wisu is more effective than on a non-acupoint. The effect size of wet cupping on Wisu and the number of subjects in a large-scale clinical trial will be calculated.
Thirty non-acute low back pain patients were randomly assigned to either the WT or NT gr oup. Three rounds of pricking-cupping bloodletting were conducted and VAS, ODI, RMDQ, EQ-5D, and FTGD were measured. VAS, the primary outcome, and ODI showed a significant reduction between baseline and follow-up in both groups.

대상 데이터

This study had two arms, the WT gr oup and NT group. Block randomization was conducted using R 3.
Forty-four participants were screened in this study. Fourteen were excluded because they either had VAS under 40 mm (n=7) or had other mor e sever e symptoms than lower back pain (n=3) or refused to participate after explanation of the procedure (n=4).
These 3 dropouts were processed with “intention to treat analysis” so each group had 15 participants for analysis.

데이터처리

Chi-square test was performed to determine the gender ratio between the WT and NT groups and Wilcoxon signed rank test was conducted to see the change between baseline and follow-up in each group. To compare groups at the same point of time, Wilcoxon rank sum test was used. A p-value lower than 0.

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