[논문]대사증후군과 알레르기 비염의 상관관계

김민아; 김인식; 이지숙

doi:10.15324/kjcls.2019.51.2.134

대사증후군과 알레르기 비염의 상관관계
Correlation between Metabolic Syndrome and Allergic Rhinitis 원문보기

Korean journal of clinical laboratory science : KJCLS = 대한임상검사과학회지, v.51 no.2, 2019년, pp.134 - 144

김민아 (을지대학교 대전캠퍼스 임상병리학과) , 김인식 (을지대학교 대전캠퍼스 임상병리학과) , 이지숙 (원광보건대학교 임상병리과)

초록
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대사증후군과 알레르기 비염은 중요한 만성질환이다. 본 연구에서는 대사증후군의 각 항목에 따른 알레르기 비염 유병률의 관계를 분석하였다. 제4, 5, 6기 및 제7기 1차년도 국민건강 영양조사 자료를 이용한 것으로(KNHANES IV, V, VI, VII-1) (2007~2016년) 이 자료를 통합하여. 51,854명의 연구대상자를 선정하였다. 연령대는 청장년(19~39세), 중년(40~64세), 노년(65세 이상)으로 분류하였다. 또 대사증후군에 영향을 미치는 일반적인 특성인 근력운동, 걷기운동, 흡연, 음주가 미치는 영향이 있다는 사실에 근거하여 조사하였다. 따라서 본 연구는 연령대 및 근력운동, 걷기운동, 흡연, 음주에 따라서 대사증후군 및 알레르기 비염의 유병률에 미치는 영향을 조사했다. 연구 결과 전 연령대에서 대사증후군이 없는 대상자가 대사증후군이 있는 대상자보다 알레르기 유병률이 높았고, 이는 연령대가 낮을 수록 알레르기 유병률이 높은 것으로 나타났다. 종합해 보면, 이 연구의 결과는 연령별, 일반적 특성별(근력운동, 걷기운동, 흡연, 음주), 대사증후군 또는 대사증후군 각각의 항목별로 알레르기 비염 유병률에 유의한 영향을 미친다는 것을 확인하였다. 본 연구에서 발견된 근거를 바탕으로 대사증후군과 알레르기 비염 유병률의 상관관계를 더 잘 이해하는데 도움이 될 것이다.

Abstract ▼ AI-Helper

Metabolic syndrome and allergic rhinitis are two important chronic diseases that affect people all over the world. Metabolic syndrome very often induces other diseases and the prevalence of allergic rhinitis is currently increasing. Aging is known to affect the pathogenesis of various diseases such as metabolic syndrome and allergy. This study examined the effects of metabolic syndrome and the prevalence of allergic rhinitis depending on different age groups and several general characteristics. This study was conducted by using the data from the Korea National Health and Nutrition Examination Survey from the 4th, 5th, 6th, and 7th-1 (2007~2016). The data used for this study was obtained from 51,854 people. In all age groups, our studies have shown that people without metabolic syndrome have a higher prevalence of allergic rhinitis than those people with metabolic syndrome, and the younger age group had the higher prevalence of allergic rhinitis (P<0.05). Overall, the results of this study found a significant effect on the prevalence of allergic rhinitis in each category of age, general characteristics (physical activity, smoking and drinking) and the presence or absence of metabolic syndrome (P<0.05). The evidence found in this study will help to understand the correlation between metabolic syndrome and allergy, and specifically allergic rhinitis.

주제어

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문제 정의

According to the KNHANES in 2016, it has been reported that the level of physical activity in adults has been continuously decreasing in Korea over the past decade [33]. The study that examined the effects of general characteristics affecting metabolic syndrome on allergic rhinitis was insufficient, so the study looked at this relationship.
It is also believed that continuous research should be conducted with accurate measurements that are excluded from subjective judgments. This study explains the correlation between diseases in statistical ways and has limitations in the extent to which it should be studied in the KNHANES. Although there is no evidence supporting the preventive effect of allergic rhinitis for cardiovascular disease risk, inflammatory responses of allergic rhinitis are related to atherosclerosis pathogenesis and metabolic conditions[34-36].
후)특성 인">특성인 근력운동, 걷기운동, 흡연, 음주가 미치는 영향이 있다는 사실에 근거하여 조사하였다. 따라서 본 연구는 연령대 및 근력운동, 걷기운동, 흡연, 음주에 따라서 대사증후군 및 알레르기 비염의 유병률에 미치는 영향을 조사했다. 연구 결과 전 연령대에서 대사증후군이 없는 대상자가 대사증후군이 있는 대상자보다 알레르기 유병률이 높았고, 이는 연령대가 연령대는 청장년(19∼39세), 중년(40∼64세), 노년(65세 이상)으로 분류하였다. 또 대사증후군에 영향을 미치는 일반적인 특성인 근력운동, 걷기운동, 흡연, 음주가 미치는 영향이 있다는 사실에 근거하여 조사하였다. 따라서 본 연구는 연령대 및 근력운동, 걷기운동, 흡연, 음주에 따라서 대사증후군 및 알레르기 비염의 유병률에 미치는 영향을 조사했다.
대사증후군과 알레르기 비염은 중요한 만성질환이다. 본 연구에서는 대사증후군의 각 항목에 따른 알레르기 비염 유병률의 관계를 분석하였다. 제4, 5, 6기 및 제7기 1차년도
제안 방법
- However, research on age and general characteristics between metabolic syndrome and allergic rhinitis is lacking. Accordingly, this study aims to study the correlation between the two diseases using the data from the Korea National Health and Nutrition Examination Survey (KNHANES) IV, V, VI and VII-1. A number of variables have been established and studied, including sex, age group, physical activity (muscle exercise, walking exercise), smoking and drinking.
- For each age group, a logistic regression analysis was conducted to verify the effects of metabolic syndrome components on allergic rhinitis, and the influences of sex, age group, muscle exercise, walking exercise, smoking, and drinking were determined (Table 7). After verifying the effects of each component of metabolic syndrome among young adults on allergic rhinitis, it was found that abnormal obesity, hyperglycemia, and hypertension did not significantly affect allergic rhinitis.
- Frequency analysis was conducted to identify the general, metabolic syndrome, and allergic rhinitis-related characteristics of this study (Table 1). A chi-squared test (x² test) was conducted to compare allergic rhinitis prevalence to general characteristics.
- Logistic regression was conducted for each component of metabolic syndrome in order to verify the effects of each component on allergic rhinitis. Similarly, the influence of sex, age group, muscle exercise, walking exercise, smoking, and drinking was corrected and analyzed (Table 5). Those with abnormal obesity had a lower prevalence of allergic rhinitis than normal (OR=0.
- The study was conducted to provide basic data on the prevalence of allergic rhinitis according to different variables found in normal adult and metabolic syndrome patients. The KNHANES showed that the prevalence of metabolic syndrome and allergic rhinitis is increasing every year, but it was difficult to find any particular relationship between the two diseases.
- The KNHANES showed that the prevalence of metabolic syndrome and allergic rhinitis is increasing every year, but it was difficult to find any particular relationship between the two diseases. Therefore, it was investigated to determine the correlation between the metabolic syndrome and allergic rhinitis in which prevalence was increasing in the course of rapidly industrializing, urbanized, and westernized lifestyles.
대상 데이터
- 후)(2007∼2016년)이">(2007∼2016년) 이 자료를 통합하여. 51,854명의 연구대상자를 선정하였다. 연령대는 청장년(19∼39세), 중년(40∼64세), 노년(65세 이상)으로 분류하였다.
- The data used in this study were prepared in accordance with the procedures and classifications presented on the KNHANES homepage. The data used in this study were from 62,421 people out of 81,503, excluding the 19,082 who were under the age of 19, and of those that remained, 10,567 had missing values in major variables, leaving 51,854. The missing values were excluded because there were no data related to metabolic syndrome and the prevalence of allergic rhinitis.

성능/효과

For each age group, a logistic regression analysis was conducted to verify the effects of metabolic syndrome components on allergic rhinitis, and the influences of sex, age group, muscle exercise, walking exercise, smoking, and drinking were determined (Table 7). After verifying the effects of each component of metabolic syndrome among young adults on allergic rhinitis, it was found that abnormal obesity, hyperglycemia, and hypertension did not significantly affect allergic rhinitis. On the other hand, hypertriglyceridemia (P=0.
In other words, young adults with hypertriglyceridemia and low HDL cholesterol may indicate a lower prevalence of allergic rhinitis. After verifying the effects of each component of metabolic syndrome on middle-aged people and the prevalence of allergic rhinitis, it was found that abnormal obesity did not significantly affect allergic rhinitis (Table 8). On the other hand, hyperglycemia, hypertriglyceridemia, hypertension, and low HDL cholesterol have been proven to have a significant effect on allergic rhinitis (P＜0.
The data used in this study were from 62,421 people out of 81,503, excluding the 19,082 who were under the age of 19, and of those that remained, 10,567 had missing values in major variables, leaving 51,854. The missing values were excluded because there were no data related to metabolic syndrome and the prevalence of allergic rhinitis. Age groups were divided into those of young adults (aged 19∼39), middle-aged people (aged 40∼64), and aged people (over 65).
Of the people who were not hyperglycemia had high prevalence of allergic rhinitis. The prevalence of allergic rhinitis with hypertriglyceridemia was 10.9%, and that of those was not hypertriglyceridemia was 15.6%. Of the people who were not hypertriglyceridemia had high prevalence of allergic rhinitis.
The correlation between metabolic syndrome and allergic rhinitis prevalence was significant. Therefore, this study is considered meaningful because it has identified the relationship between two diseases, metabolic syndrome and allergic rhinitis, which have increased prevalence among Koreans. In this regard, the factors that affect metabolic syndrome and allergic diseases excluded from this study should be investigated.
따라서 본 연구는 연령대 및 근력운동, 걷기운동, 흡연, 음주에 따라서 대사증후군 및 알레르기 비염의 유병률에 미치는 영향을 조사했다. 연구 결과 전 연령대에서 대사증후군이 없는 대상자가 대사증후군이 있는 대상자보다 알레르기 유병률이 높았고, 이는 연령대가 낮을 수록 알레르기 유병률이 높은 것으로 나타났다. 후)종합해보면,">종합해 보면, 이 연구의 결과는 연령별, 일반적 특성별(근력운동, 걷기운동, 흡연, 음주), 대사증후군 또는 대사증후군 각각의 항목별로 알레르기 비염 유병률에 유의한 영향을 미친다는 것을 확인하였다. 본 연구에서 발견된 근거를 바탕으로 대사증후군과 알레르기 비염 유병률의 상관관계를 더 잘
후속연구
- 후)종합해보면,">종합해 보면, 이 연구의 결과는 연령별, 일반적 특성별(근력운동, 걷기운동, 흡연, 음주), 대사증후군 또는 대사증후군 각각의 항목별로 알레르기 비염 유병률에 유의한 영향을 미친다는 것을 확인하였다. 본 연구에서 발견된 근거를 바탕으로 대사증후군과 알레르기 비염 유병률의 상관관계를 더 잘 이해하는데 도움이 될 것이다.

참고문헌 (36)

Lim HK, Sull JW, Park BS, Mun JY, Hong MH, Lee Y, et al. Relationship of metabolic diseases with physical activity depending on age. Korean J Clin Lab Sci. 2018;50:144 -154. https://doi.org/10.15324/kjcls.2018.50.2.144.

원문보기 상세보기
Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults. Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III). JAMA. 2001;285:2486-2497.

상세보기
Hwang YC, Jee JH, Oh EY, Choi YH, Lee MS, Kim KW, et al. Metabolic syndrome as a predictor of cardiovascular diseases and type diabetes in Koreans. Int J Cardiol. 2009;134:313-321. https://doi.org/10.1016/j.ijcard.2008.12.025.

상세보기
Skoner DP. Allergic rhinitis definition, epidemiology, pathophysiology, detection and diagnosis. J Allergy Clin Immunol. 2001;108:S2-8.

상세보기
Asher MI, Montefort S, Bjorksten B, Lai CK, Strachan DP, Weiland SK, et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC phase one and three repeat multicountry cross-sectional survey. Lancet. 2006;368:733-743. https://doi.org/10.1016/S0140-6736(06)69283-0.

상세보기
Hong SJ, Ahn KM, Lee SY, Kim KE. The prevalences of asthma and allergic diseases in Korean children. Pediatr Allergy Respir Dis. 2008;18:15-25.
Kim IS, Lee JS. The development of diagnosis for atopic dermatitis by evaluating expression of skin barrier proteins using non-invasive method. Korean J Clin Lab Sci. 2017;49: 395-400. https://doi.org/10.15324/kjcls.2017.49.4.395.

원문보기 상세보기
Seong HU, Cho SD, Park SY, Yang JM, Lim DH, Kim JH, et al. Nationwide survey on the prevalence of allergic diseases according to region and age. Pediatr Allergy Respir Dis. 2012;22:224-231.

상세보기
Seo MH, Lee WY, Kim SS, Kang JH, Kang JH, Kim KK et al. 2018 Korean society for the study of obesity guideline for the management of obesity in Korea. J Obes Metab Syndr. 2019; 28:40-45. https://doi.org/10.7570/jomes.2019.28.1.40.

상세보기
Bousquet J, Van Cauwenberge P, Khaltaev N; Aria Workshop Group; World Health Organization. Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol. 2001;108(5 Suppl):147-334.

상세보기
Park JS, Park HD, Yun JW, Jung CH, Lee WY, Kim SW. Prevalence of the metabolic syndrome as defined by NCEPATPIII among the urban Korean population. Korean J Med. 2002;63:290-299.
Bo S, Ciccone Gm Baldi C, Benini L, Dusio F, Forastiere G, et al. Effectiveness of lifestyle intervention on metabolic syndrome. A randomized controlled trial. J Gen Intern Med. 2007; 22:1695-1703. https://doi.org/10.1007/s11606-007-0399-6.

상세보기
Jahangiry L, Shojaeizadeh D, Montaazeri A, Najafi M, Mohammad K, Abbasalizad Farhangi M. Modifiable lifestyle risk factors and metabolic syndrome: opportunities for a webbased preventive program. J Res Health Sci. 2014;14:303-307.

상세보기
Yoon YS, Oh SW, Baik HW, Park HS, Kim WY. Alcohol consumption and the metabolic syndrome in Korean adults: the 1998 Korean National Health and Nutrition Examination Survey. Am J Clin Nutr. 2004;80:217-224. https://doi.org/10.1093/ajcn/80.1.217.

상세보기
Kang SY, Song WJ, Cho SH. Chang YS. Time trends of the prevalence of allergic diseases in Korea: A systematic literature review. Asia Pac Allergy. 2018;8:E8. https://doi.org/10.5415/apallergy.2018.8.e8.

상세보기
Larsson Ulf, Taft C, Karlsson J, Sullivan M. Gender and age differences in the relative burden of rhinitis and asthma on health-related quality of life-a Swedish population study. Respir Med. 2007;101:1291-1298. https://doi.org/10.1016/j.rmed.2006.10.014.

상세보기
Mjos OD. Lipid effects of smoking. Am Heart J. 1998;115:272-275.
Oh JE. Association between smoking status and metabolic syndrome in Men. Korean J Obes. 2014;23:99-105. http://dx.doi.org/10.7570/kjo.2014.23.2.99.

상세보기
Park JE, Ryu Y, Cho SI. The effect of reference group classification and change in alcohol consumption on the association between alcohol consumption and cardiovascular disease. Alcohol Clin Exp Res. 2017;41:379-387. http://dx.doi.org/10.1111/acer.13299.

상세보기
Wilsgaard T. Jacobsen BK. Lifestyle factors and incident metabolic syndrome. The Tromso Study 1979-2001. Diabetes Res Clin Prac. 2007;78:217-224. http://dx.doi.org/10.1016/j.diabres.2007.03.006.

상세보기
Wannamethee SG, Shaper AG, Whincup PH. Alcohol and adiposity: effects of quantity and type of drink and time relation with meals. Int J Obes. 2005;29:1436-1444. https://doi.org/10.1038/sj.ijo.0803034.

상세보기
Santos AC, Ebrahim S, Barros H. Alcohol intake, smoking, sleeping hours, physical activity and the metabolic syndrome. PrevMed. 2007;44:328-334. https://doi.org/10.1016/j.ypmed.2006.11.016.

상세보기
Kim BJ, Kim BS, Kang JH. Alcohol consumption and incidence of metabolic syndrome in Korean men. A 3-year follow-up study. Circ J. 2012;76:2363-2371.

상세보기
Thompson PD1, Arena R, Riebe D, Pescatello LS; American College of Sports Medicine. ACSM's new preparticipation health screening recommendation from ACSM's guidelines for exercise testing and prescription, ninth edition. Curr Sports Med Rep. 2013;12:215-217. https://doi.org/10.1249/JSR.0b013e31829a68cf.

상세보기
Diabetes Prevention Program (DPP) Research Group. The diabetes prevention program (DPP): description of lifestyle intervention. 2002;25:2165-2171. https://doi.org/10.2337/diacare.25.12.2165.

상세보기
Kelley DE, Wing R, Buonocore C, Sturis J, Polonsky K, Fitzsimmons M. Relative effects of calorie restriction and weight loss in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 1993;77:1287-1293. https://doi.org/10.1210/jcem.77.5.8077323.

상세보기
Jenkins DJ, Kendall CW, Augustin LS, Franceschi S, Hamidi M, Marchie A, et al. Glycemic index: overview of implications in health and disease. Am J Clin Nutr. 2002;76:266-273. https://doi.org/10.1093/ajcn/76/1.266S.

상세보기
Kim DH, So WY, Kim JS. Patterns of physical activity and metabolic syndrome among adult Koreans: a cross sectional study. Southeast Asian J Trop Med Public Health. 2014;45:1202-1208.

상세보기
Rennie KL, McCarthy N, Yazdgerdi S, Marmot M, Brunner E. Association of the metabolic syndrome with both vigorous and moderate physical activity. Int J Epidemiol. 2003;32:600-606. http://dx.doi.org/10.1093/ije/dyg179.

상세보기
Choi M, Yeom HA, Jung D. Association between physical activity and metabolic syndrome in older adults in Korea: analysis of data from the Korean National Health and Nutrition Examination survey IV. Nurs Health Sci. 2013;15:379-386. http://dx.doi.org/10.1111/nhs.12045.

상세보기
Wu S, Fisher-Hoch SP, Reininger B, McCormick JB. Recommended levels of physical activity are associated with reduced risk of the metabolic syndrome in Mexican-Americans. PLoS One. 2016;11:E0152896. http://dx.doi.org/10.1371/journal.pone. 0152896.

상세보기
Ko KJ, Kim EH, Baek UH, Gang Z, Kang SJ. The relationship between physical activity levels and metabolic syndrome in male white-collar workers. J Phys Ther Sci. 2016;28:3041-3046. http://dx.doi.org/10.1589/jpts.28.3041.

상세보기
Korea Centers for Disease Control and Prevention. Korea health statistics 2015: Korea national health and nutrition examination survey (KNHANES VI-3). Sejong: Ministry of Health and Welfare; 2016.
Wang J, Cheng X, Xiang MX, Alanne-Kinnunen M, Wang JA, Chen H, et al. IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice. J Clin Invest. 2011;121:3564-3577. http://dx.doi.org/10.1172/JCI46028.

상세보기
Jawien J, Korbut R. The current view on the role of leukotrienes in atherogenesis. J Physiol Pharmacol. 2010;61:647-650.
Hwang IC, Lee YJ, Ahn HY, Lee SM. Association between allergic rhinitis and metabolic conditions: a nationwide survey in Korea. Allergy Asthma Clin Imunol. 2016;12:5. http://dx.doi.org/10.1186/s13223-015-0108-7.

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구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

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