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폐암 한약제제 임상시험 가이드라인 개발을 위한 한약제제 무작위배정 대조군 임상시험 고찰
Analysis of Existing Guidelines and Randomized, Controlled, Clinical Trials for Development of [Guideline of Clinical Trial with Herbal Medicinal Product for Lung Cancer] 원문보기

Journal of Korean Medicine = 대한한의학회지, v.40 no.1, 2019년, pp.153 - 173  

한가진 (소람한방병원) ,  조민지 (소람한방병원) ,  박은주 (소람한방병원) ,  성신 (소람한방병원) ,  김성수 (소람한방병원) ,  김관일 (경희대학교 한의과대학 폐계내과학 교실) ,  정희재 (경희대학교 한의과대학 폐계내과학 교실) ,  이범준 (경희대학교 한의과대학 폐계내과학 교실) ,  임정태 (청연중앙연구소)

Abstract AI-Helper 아이콘AI-Helper

Objectives: This study aimed to ascertain what should be considered in the "Guideline for Clinical Trials with Herbal Medicinal Products for Lung Cancer" by analyzing the existing guidelines and clinical trials. Methods: The committee searched guidelines and clinical trials about herbal medicine for...

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핵심어 질문 논문에서 추출한 답변
폐암의 종류는 어떠한 것들로 구분하는가?  폐암의 종류는 암세포의 크기와 형태를 기준으로 비소세포 폐암과 소세포 폐암으로 구분한다. 폐암 가운데 80~85%는 비소세포 폐암인데, 이것은 다시 선암(샘암), 편평상피세포암, 대세포암 등으로 나뉜다.
근거중심의학이 무엇인가?  근거중심의학이란 의사들이 논문을 찾고 분석만 하는 것이 아니라 이를 실제 환자진료에 활용하는 것을 의미한다38). 이러한 근거중심의학을 실행하기 위한 첫 번째 단계는 구체적이고 답변 가능한 임상질문을 만드는 것인데, 이 질문의 네 가지 요소는 임상시험대상자(P), 중재군(I), 대조군(C), 결과(O)이다39).
대부분의 폐암환자는 항암화학요법을 받는다. 항암화학요법의 부작용은 무엇인가? 폐암의 최선의 치료방법은 수술이 가능할 경우 완전 절제를 하는 것이나 조기병변이라 할지라도 수술 후 재발율이 높으며, 진단 당시에 이미 절반 이상의 환자에게서 전이 소견을 보여 수술이 불가능한 경우가 많아 대부분의 폐암환자는 항암화학요법을 받는다5),6). 그런데 항암화학요법은 암세포뿐 아니라 모공세포, 위장관내 점막세포, 피부, 구강 내 상피세포, 골수와 같은 성장이 빠른 정상세포에 악영향을 끼치는 부작용을 초래하여7)항암화학요법 중인 폐암 환자는 호흡곤란, 피로, 통증, 식욕부진, 수면장애, 변비, 오심과 구토, 설사 등을 호소한다8). 그러나 서양의학의 기존 의료 체계 내에서는 이러한 부작용에 대한 적절한 치료 및 전문적인 관리가 부족한 상황으로9), 많은 암환자들이 암 치료 과정에서 겪게 되는 심각한 부작용의 해결을 위해 효과가 있다고 알려진 보완대체 의학을 사용하고 있다10).
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