[논문]국내산 블렌딩 정유의 항산화 및 항염 효과 연구

정숙희; 이은경

doi:10.12925/jkocs.2021.38.6.1370

국내산 블렌딩 정유의 항산화 및 항염 효과 연구
A study on antioxidant and anti-inflammatory effects of domestic blended essential oils 원문보기

Journal of the Korean Applied Science and Technology = 한국응용과학기술학회지, v.38 no.6, 2021년, pp.1370 - 1382

정숙희 (남부대학교 향장미용학과) , 이은경 (남부대학교 산학협력단 치유향기상용화사업단)

초록
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국내산 소재를 이용한 단일 추출물의 안전성 실험 및 화장품 소재로써의 선행 연구는 실시되어 왔지만, 개별 추출하여 식물의 특성을 극대화 및 효과 간섭 가능성에 대한 복합 혼합물에 대한 연구가 미비한 상황이다. 이에 본 연구는 배초향, 적송, 강황, 생강, 산미나리씨, 불수감에 대한 정유 추출에 따른 GC-MSD, 블렌딩 오일의 세포독성, 항산화, 항염을 확인하여 화장품 소재로서의 가능성을 확인하였다. GC-MSD 향기성분을 분석한 결과 주요 성분으로는 배초향은 Estragole, 적송은 à-Pinene, 강황과 생강은 Zingiberene, 산미나리씨 Anethole, 불수감 D-Limonene이 동정되었다. 세포독성이 확인되지 않은 100 uL/mL의 농도에서 NO 생성 70.62% 억제, DPPH 라디칼 소거능 64.03%, ABTS 라디칼 소거능 89.55%을 보였다. 이를 통하여 블렌딩 정유는 화장품 및 식품, 의약품 산업 분야에서 항산화 및 항염 효능이 있는 원료로서 유용하게 활용할 수 있는 가능성을 제시하였다.

Abstract ▼ AI-Helper

Previous studies have been conducted on domestic materials as a single extract. Research on complex mixtures for maximizing plant characteristics by individual extraction and potential interference with effects is insufficient. Therefore, this study confirmed the GC-MSD according to the extraction of essential oils for Agastache rugosa O. Kuntze(AR), Pinus densiflora Sieb. et Zuccarini(PD), Curcuma longa, Curcuma domestica(CC), Zingiber officinale Roscoe(ZR), Foeniculum vulgare Miller(FV), and Citrus medica L. var. sarcodactylis Swingle(CS). The cytotoxicity, antioxidant, and anti-inflammatory properties of the blending oil were confirmed to confirm its potential as a cosmetic material. As a result of analyzing GC-MSD aroma components, the main components were estragole of AR, à-Pinene for PD, Zingiberene for CC and ZR, Anethole from FV, and D-Limonene for CS. At a concentration of 100 uL/mL with no confirmed cytotoxicity, NO production was inhibited by 70.62%, DPPH radical scavenging activity was 64.03%, and ABTS radical scavenging activity was 89.55%. Through this, blended essential oil suggests the possibility of useful application as a raw material with antioxidant and anti-inflammatory effects in the cosmetic and food industries.

주제어

표/그림 (11)

표 Table 1. Yields of steam distillation extracts from AR, PD, CC, ZR, FV, CS
표 Table 2. Chemical composition of the volatile oil constituents of AR determined by GC-MSD analysis
표 Table 3. Chemical composition of the volatile oil constituents of PD determined by GC-MSD analysis
표 Table 4. Chemical composition of the volatile oil constituents of CC determined by GC-MSD analysis
표 Table 5. Chemical composition of the volatile oil constituents of ZR determined by GC-MSD analysis
표 Table 6. Chemical composition of the volatile oil constituents of FV determined by GC-MSD analysis
그림 Fig. 1. Effect of viability of cells treated with HE in Raw 264.7 cell. Data are presented as mean±SD. HE: The volatile oil constituents of Six Natural Herbs Essential oil Mixture. *p<0.05 compared with the negative control
표 Table 7. Chemical composition of the volatile oil constituents of CS determined by GC-MSD analysis
그림 Fig. 2. Effect of anti-oxidant effects of HE by DPPH radical scavenging. HE: The volatile oil constituents of Six Natural Herbs Essential oil Mixture. Data are presented as mean±SD. *p<0.05 compared with the negative control
그림 Fig. 3. Effect of anti-oxidant effects of HE by ABTS radical scavenging. HE: The volatile oil constituents of Six Natural Herbs Essential oil Mixture. Data are presented as mean±SD. *p<0.05 compared with the negative control
그림 Fig. 4. Effect of inhibition of NO production of HE. HE: The volatile oil constituents of Six Natural Herbs Essential oil Mixture. Data are presented as mean±SD. *p<0.05 compared with the negative control

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표제어: PCR

동의어: Packet Collision Rate

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