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NTIS 바로가기Korean chemical engineering research = 화학공학, v.59 no.1, 2021년, pp.106 - 111
박지민 (공주대학교 화학공학부) , 김진현 (공주대학교 화학공학부)
In this study, an ultrasound-assisted micellar extraction process was developed to efficiently purify the anticancer substance paclitaxel from the plant cell Taxus chinensis. The problem of many extraction steps and long phase separation time in the traditional micellar process could be dramatically...
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Kang, H. J. and Kim, J. H., "Removal of Residual Toluene and Methyl Tertiary Butyl Ether from Amorphous Paclitaxel by Simple Rotary Evaporation with Alcohol Pretreatment," Biotechnol. Bioprocess Eng., 25, 86-93(2020).
Yang, J. W. and Kim, J. H., "Evaluation of Adsorption Characteristics of 2-picoline Onto Sylopute," Korean Chem. Eng. Res., 57, 210-218(2019).
Hsiao, J. R., Leu, S. F. and Huang, B. M., "Apoptotic Mechanism of Paclitaxel Induced Cell Death in Human Head and Neck Tumor Cell Lines," J. Oral Pathol. Med., 38, 188-197(2009).
Rao, K. V., Hanuman, J. B., Alvarez, C., Stoy, M., Juchum, J., Davies, R. M. and Baxley, R., "A New Large-scale Process for Taxol and Related Taxanes from Taxus brevifolia", Pharm. Res., 12, 1003-1010(1995).
Baloglu, E. and Kingston, D. G., "A New Semisynthesis of Paclitaxel from Baccatin III," J. Nat. Prod., 62, 1068-1071(1999).
Kang, H. J. and Kim, J. H., "Removal of Residual Chloroform from Amorphous Paclitaxel Pretreated by Alcohol," Korean J. Chem. Eng., 36, 1965-1970(2019).
Pyo, S. H., Park, H. B., Song, B. K., Han, B. H. and Kim, J. H., "A Large-scale Purification of Paclitaxel from Cell Cultures of Taxus chinensis", Process Biochem., 39, 1985-1991(2004).
Seo, H. W. and Kim, J. H., "Ultrasound-assisted Fractional Pre-Cipitation of Paclitaxel from Taxus chinensis Cell Cultures," Process Biochem., 87, 238-243(2019).
Kim, J. H., "Prepurification of Paclitaxel by Micelle and Precipitation," Process Biochem., 39, 1567-1571(2004).
Zhu, K. X., Sun, X. H. and Zhou, H. M., "Optimization of Ultrasound-assisted Extraction of Defatted Wheat Germ Proteins by Reverse Micelles," J. Cereal Sci., 50, 266-271(2009).
Jeon, K. Y. and Kim, J. H., "Effect of Surfactant on the Micelle Process for the Pre-purification of Paclitaxel," Korean J. Biotechnol. Bioeng., 23, 557-560(2008).
Han, M. G., Jeon, K. Y., Mun, S. and Kim, J. H., "Development of a Micelle-fractional Precipitation Hybrid Process for the Prepurification of Paclitaxel from Plant Cell Cultures," Process Biochem., 45, 1368-1374(2010).
Tan, Z., Li, Q., Wang, C., Zhou, W., Yang, Y., Wang, H., Yi, Y. and Li, F., "Ultrasonic Assisted Extraction of Paclitaxel from Taxus x media Using Ionic Liquids as Adjuvants: Optimization of the Process by Response Surface Methodology," Molecules, 22, 1483-1493 (2017).
Patil, S. S. and Rathod, V. K., "Synergistic Effect of Ultrasound and Three Phase Partitioning for the Extraction of Curcuminoids from Curcuma longa and Its Bioactivity Profile," Process Biochem., 93, 85-93(2020).
Cao, J., Peng, L. Q., Du, L. J., Zhang, Q. D. and Xu, J. J., "Ultrasound-assisted Ionic Liquid-based Micellar Extraction Combined with Microcrystalline Cellulose as Sorbent in Dispersive Micro-extraction for the Determination of Phenolic Compounds in Propolis," Anal. Chim. Acta, 963, 24-32(2017).
Ziyatdinova, G., Ziganshina, E., Cong, P. N. and Budnikov, H., "Ultrasound-assisted Micellar Extraction of Phenolic Antioxidants from Spices and Antioxidant Properties of the Extracts Based on Coulometric Titration Data," Anal. Methods, 8, 7150-7157(2016).
Kim, J. H., "Comparison of Conventional Solvent Extraction, Microwave-assisted Extraction, and Ultrasound-assisted Extraction Methods for Paclitaxel Recovery from Biomass," Korean Chem. Eng. Res., 58, 273-279(2020).
Guo, Y. X., Han, J., Zhang, D. Y., Wang, L. H. and Zhou, L. L., "An Ammonium Sulfate/ethanol Aqueous Two-phase System Combined with Ultrasonication for the Separation and Purification of Lithospermic Acid B from Salvia miltiorrhiza Bunge," Ultrason. Sonochem., 19, 719-724(2012).
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