[논문]Current Issues and Technical Advances in Cultured Meat Production: A Review

Hong, Tae Kyung; Shin, Dong-Min; Choi, Joonhyuk; Do, Jeong Tae; Han, Sung Gu

doi:10.5851/kosfa.2021.e14

Current Issues and Technical Advances in Cultured Meat Production: A Review 원문보기

Food science of animal resources, v.41 no.3, 2021년, pp.355 - 372

Hong, Tae Kyung (Department of Stem Cell and Regenerative Biotechnology, KU Institute of Science and Technology, Konkuk University) , Shin, Dong-Min (Department of Food Science and Biotechnology of Animal Resources, Konkuk University) , Choi, Joonhyuk (Department of Stem Cell and Regenerative Biotechnology, KU Institute of Science and Technology, Konkuk University) , Do, Jeong Tae (Department of Stem Cell and Regenerative Biotechnology, KU Institute of Science and Technology, Konkuk University) , Han, Sung Gu (Department of Food Science and Biotechnology of Animal Resources, Konkuk University)

Abstract ▼ AI-Helper

As the global population grows, we need a stable protein supply to meet the demands. Although plant-derived protein sources are widely available, animal meat maintains its popularity as a high-quality and savory protein source. Recently, cultured meat, also known as in vitro meat, has been suggested as a meat analog produced through in vitro cell culture technology. Cultured meat has several advantages over conventional meat, such as environmental protection, disease prevention, and animal welfare. However, cultured meat manufacturing is an emerging technology; thus, its further and dynamic development would be pivotal. Commercialization of cultured meat to the public will take a long time but cultured meat undoubtedly will come to our table someday. Here, we discuss the social and economic aspects of cultured meat production as well as the recent technical advances in cultured meat technology.

주제어

표/그림 (4)

표 Table 1. Comparison of traditional and cultured meat
그림 Fig. 1. Muscle satellite cell myogenic differentiation pathway with expressing markers. Muscle satellite cells potential for differentiating into muscle fibre. Quiescent satellite cells express paired box 7 (Pax7) while myogenic factor 5 (Myf5) is downregulated. In the process of developing into myoblast and muscle fibre, satellite cells are proliferated as well as differentiated. Myogenic determination (MyoD) and myogenin (Myog) marks the production of more complex filaments while differentiation undergoes.
표 Table 2. Diverse cultured meat products currently being developed
그림 Fig. 2. Technical approach for producing cultured meat. Adult stem cells and induced pluripotent stem (iPS) cells could both be considered cultured meat sources. Myogenic satellite cells and adipose stem cells are proliferated through in vitro culturing and manufactured to resemble meat structure. iPS cells could differentiate into several different cell types comprising muscle tissue that could be used, along with multiple other cell types, to manufacture three-dimensional (3D) structures using tissue engineering or bioprinting technologies.

참고문헌 (135)

Adal MN Cheng SBC 1980 Capsules of duck muscle spindles Cell Tissue Res 211 465 474 10.1007/BF00234400 6448090

상세보기
Alexander P Brown C Arneth A Dias C Finnigan J Moran D Rounsevell MDA 2017 Could consumption of insects, cultured meat or imitation meat reduce global agricultural land use? Glob Food Secur 15 22 32 10.1016/j.gfs.2017.04.001

상세보기
Alexander R 2011 In vitro meat: A vehicle for the ethical rescaling of the factory farming industry and in vivo testing or an intractable enterprise? Intersect: Stanf J Sci Technol Soc 4 42 47
Ali A Ahmed S 2018 Recent advances in edible polymer based hydrogels as a sustainable alternative to conventional polymers J Agric Food Chem 66 6940 6967 10.1021/acs.jafc.8b01052 29878765

상세보기
Allen RE Merkel RA Young RB 1979 Cellular aspects of muscle growth: Myogenic cell proliferation J Anim Sci 49 115 127 10.2527/jas1979.491115x 500507

상세보기
Arshad MS Javed M Sohaib M Saeed F Imran A Amjad Z 2017 Tissue engineering approaches to develop cultured meat from cells: A mini review Cogent Food Agric 3 1320814 10.1080/23311932.2017.1320814

상세보기
Bánáti D 2011 Consumer response to food scandals and scares Trends Food Sci Technol 22 56 60 10.1016/j.tifs.2010.12.007

상세보기
BBC News 2013 World’s first lab-grown burger is eaten in London Available from https://www.bbc.com/news/science-environment-23576143 Accessed at Mar 12, 2021
Ben-Arye T Levenberg S 2019 Tissue engineering for clean meat production Front Sustain Food Syst 3 46 10.3389/fsufs.2019.00046

상세보기
Ben-Arye T Shandalov Y Ben-Shaul S Landau S Zagury Y Ianovici I Lavon N Levenberg S 2020 Textured soy protein scaffolds enable the generation of three-dimensional bovine skeletal muscle tissue for cell-based meat Nat Food 1 210 220 10.1038/s43016-020-0046-5

상세보기
Bhat ZF Bhat H Pathak V 2014 Prospects for in vitro cultured meat: A future harvest In Principles of tissue engineering 4 th ed Lanza R Langer R Joseph Vacanti (ed) Elsevier San Diego, CA, USA 1663 1683 10.1016/B978-0-12-398358-9.00079-3
Bhat ZF Fayaz H 2011 Prospectus of cultured meat—advancing meat alternatives J Food Sci Technol 48 125 140 10.1007/s13197-010-0198-7

상세보기
Bhat ZF Hina B 2011 Animal-free meat biofabrication Am J Food Technol 6 441 459 10.3923/ajft.2011.441.459

상세보기
Bhat ZF Kumar S Fayaz H 2015 In vitro meat production: Challenges and benefits over conventional meat production J Integr Agric 14 241 248 10.1016/S2095-3119(14)60887-X

상세보기
Bhat ZF Morton JD Mason SL Bekhit AEDA Bhat HF 2019 Technological, regulatory, and ethical aspects of in vitro meat: A future slaughter-free harvest Compr Rev Food Sci Food Saf 18 1192 1208 10.1111/1541-4337.12473 33336995

상세보기
Bischoff R 1974 Enzymatic liberation of myogenic cells from adult rat muscle Anat Rec 180 645 661 10.1002/ar.1091800410 4374100

상세보기
Bischoff R 1975 Regeneration of single skeletal muscle fibers in vitro Anat Rec 182 215 235 10.1002/ar.1091820207 168794

상세보기
Bodiou V Moutsatsou P Post MJ 2020 Microcarriers for upscaling cultured meat production Front Nutr 7 10 10.3389/fnut.2020.00010 32154261

상세보기
Bonny SPF Gardner GE Pethick DW Hocquette JF 2015 What is artificial meat and what does it mean for the future of the meat industry? J Integr Agric 14 255 263 10.1016/S2095-3119(14)60888-1

상세보기
Brack AS Conboy IM Conboy MJ Shen J Rando TA 2008 A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis Cell Stem Cell 2 50 59 10.1016/j.stem.2007.10.006 18371421

상세보기
Braun T Gautel M 2011 Transcriptional mechanisms regulating skeletal muscle differentiation, growth and homeostasis Nat Rev Mol Cell Biol 12 349 361 10.1038/nrm3118 21602905

상세보기
Brodwin E 2018a A new lab-grown meat startup may have overcome a key barrier to making meat without slaughter Available from https://www.businessinsider.com/lab-grown-meat-startup-solving-barrier-meat-without-slaughter-meatable-2018-9 Accessed at Mar 12, 2021
Brodwin E 2018b The startup behind the first lab-grown pork links let us see how their sausage gets made – and said it slashed the cost from $2,500 to $216 in a month Available from https://www.businessinsider.com/taste-test-lab-grown-meat-sausage-cost-2018-11 Accessed at Mar 12, 2021
Bryant C Dillard C 2019 The impact of framing on acceptance of cultured meat Front Nutr 6 103 10.3389/fnut.2019.00103 31334244

상세보기
Bryant C Szejda K Parekh N Desphande V Tse B 2019 A survey of consumer perceptions of plant-based and clean meat in the USA, India, and China Front Sustain Food Syst 3 11 10.3389/fsufs.2019.00011

상세보기
Bryant CJ 2020 Culture, meat, and cultured meat J Anim Sci 98 skaa172 10.1093/jas/skaa172 32745186

상세보기
Chen G Cheng X Shi G Zou C Chen L Li J Li M Fang C Li C 2019 Transcriptome analysis reveals the effect of long intergenic noncoding RNAs on pig muscle growth and fat deposition BioMed Res Int 2019 2951427 10.1155/2019/2951427 31341893

상세보기
Cheng YW Shiwarski DJ Ball RL Whitehead KA Feinberg AW 2020 Engineering aligned skeletal muscle tissue using decellularized plant-derived scaffolds ACS Biomater Sci Eng 6 3046 3054 10.1021/acsbiomaterials.0c00058 33463300

상세보기
Choi HW Kim JS Choi S Ju Hong Y Byun SJ Seo HG Do JT 2016a Mitochondrial remodeling in chicken induced pluripotent stem-like cells Stem Cells Dev 25 472 476 10.1089/scd.2015.0299 26795691

상세보기
Choi YJ Jun YJ Kim DY Yi HG Chae SH Kang J Lee J Gao G Kong JS Jang J Chung WK Rhie JW Cho DW 2019 A 3D cell printed muscle construct with tissue-derived bioink for the treatment of volumetric muscle loss Biomaterials 206 160 169 10.1016/j.biomaterials.2019.03.036 30939408

상세보기
Choi YJ Kim TG Jeong J Yi HG Park JW Hwang W Cho DW 2016b 3D cell printing of functional skeletal muscle constructs using skeletal muscle-derived bioink Adv Healthc Mater 5 2636 2645 10.1002/adhm.201600483 27529631

상세보기
Choudhury D Tseng TW Swartz E 2020 The business of cultured meat Trends Biotechnol 38 573 577 10.1016/j.tibtech.2020.02.012 32407686

상세보기
Chriki S Hocquette JF 2020 The myth of cultured meat: A review Front Nutr 7 7 10.3389/fnut.2020.00007 32118026

상세보기
Cole M Morgan K 2013 Engineering freedom? A critique of biotechnological routes to animal liberation Configurations 21 201 229 10.1353/con.2013.0015

상세보기
Crew B 2015 Cost of lab-grown burger patty drops from $325,000 to $11.36 Available from https://www.sciencealert.com/lab-grown-burger-patty-cost-drops-from-325-000-to-12 Accessed at Mar 12, 2021
Datar I Betti M 2010 Possibilities for an in vitro meat production system Innov Food Sci Emerg Technol 11 13 22 10.1016/j.ifset.2009.10.007

상세보기
Dayton WR White ME 2008 Cellular and molecular regulation of muscle growth and development in meat animals J Anim Sci 86 E217 E225 10.2527/jas.2007-0456 17709769

상세보기
Dilworth T McGregor A 2015 Moral steaks? Ethical discourses of in vitro meat in Academia and Australia Agric Environ Ethics 28 85 107 10.1007/s10806-014-9522-y

상세보기
Ding S Wang F Liu Y Li S Zhou G Hu P 2017 Characterization and isolation of highly purified porcine satellite cells Cell Death Discov 3 17003 10.1038/cddiscovery.2017.3 28417015

상세보기
Dodson MV Allen RE Du M Bergen WG Velleman SG Poulos SP Fernyhough-Culver M Wheeler MB Duckett SK Young MRI Voy BH Jiang Z Hausman GJ 2015 Invited review: Evolution of meat animal growth research during the past 50 years: Adipose and muscle stem cells J Anim Sci 93 457 481 10.2527/jas.2014-8221 26020737

상세보기
Dodson MV Martin EL Brannon MA Mathison BA McFarland DC 1987 Optimization of bovine satellite cell-derived myotube formation in vitro Tissue Cell 19 159 166 10.1016/0040-8166(87)90001-2 3590147

상세보기
Dodson MV McFarland DC Martin EL Brannon MA 1986 Isolation of satellite cells from ovine skeletal muscles J Tissue Cult Methods 10 233 237 10.1007/BF01404483

상세보기
Dorovskikh A 2015 Killing for a living: Psychological and physiological effects of alienation of food production on slaughterhouse workers Undergraduate honors theses University of Colorado Boulder Boulder, CO, USA
Doumit ME Merkel RA 1992 Conditions for isolation and culture of porcine myogenic satellite cells Tissue Cell 24 253 262 10.1016/0040-8166(92)90098-R 1589873

상세보기
Du M Tong J Zhao J Underwood KR Zhu M Ford SP Nathanielsz PW 2010 Fetal programming of skeletal muscle development in ruminant animals J Anim Sci 88 E51 E60 10.2527/jas.2009-2311 19717774

상세보기
Dumont NA Wang YX Rudnicki MA 2015 Intrinsic and extrinsic mechanisms regulating satellite cell function Development 142 1572 1581 10.1242/dev.114223 25922523

상세보기
FAO [Food and Agriculture of the United Nations] 2012 Agriculture organization of the United Nations FAO Statistical Yearbook. FAO Rome, Italy
Feldman JL Stockdale FE 1991 Skeletal muscle satellite cell diversity: Satellite cells form fibers of different types in cell culture Dev Biol 143 320 334 10.1016/0012-1606(91)90083-F 1991555

상세보기
Gey GO 1933 An improved technic for massive tissue culture Am J Cancer 17 752 756
Godfray HCJ 2019 Meat: The future series alternative proteins World Economic Forum 1 33
Goodwin JN Shoulders CW 2013 The future of meat: A qualitative analysis of cultured meat media coverage Meat Sci 95 445 450 10.1016/j.meatsci.2013.05.027 23793078

상세보기
Gourmey Gourmey savoir-faire 2020 Available from https://gourmey.com/en/#savoir-faire Accessed at Mar 12, 2021
Greene EA Raub RH 1992 Procedures for harvesting satellite cells from equine skeletal muscle J Equine Vet Sci 12 33 35 10.1016/S0737-0806(06)81383-3

상세보기
Greenlee AR Dodson MV Yablonka-Reuveni Z Kersten CA Cloud JG 1995 In vitro differentiation of myoblasts from skeletal muscle of rainbow trout J Fish Biol 46 731 747 10.1111/j.1095-8649.1995.tb01597.x

상세보기
Grinnell F 1978 Cellular adhesiveness and extracellular substrata Int Rev Cytol Elsevier 53 65 144 10.1016/S0074-7696(08)62241-X
Han B Tong J Zhu MJ Ma C Du M 2008 Insulin-like growth factor-1 (IGF-1) and leucine activate pig myogenic satellite cells through mammalian target of rapamycin (mTOR) pathway Mol Reprod Dev 75 810 817 10.1002/mrd.20832 18033679

상세보기
Han X Han J Ding F Cao S Lim SS Dai Y Zhang R Zhang Y Lim B Li N 2011 Generation of induced pluripotent stem cells from bovine embryonic fibroblast cells Cell Res 21 1509 1512 10.1038/cr.2011.125 21826109

상세보기
Hoek AC Luning PA Stafleu A de Graaf C 2004 Food-related lifestyle and health attitudes of Dutch vegetarians, non-vegetarian consumers of meat substitutes, and meat consumers Appetite 42 265 272 10.1016/j.appet.2003.12.003 15183917

상세보기
Hoekstra AY Chapagain AK 2006 Water footprints of nations: Water use by people as a function of their consumption pattern In Integrated assessment of water resources and global change Craswell E Bonnell M Bossio D Demuth S van de Giesen N (ed) Springer Dordrecht, Netherlands 35 48 10.1007/978-1-4020-5591-1_3
Hopkins PD Dacey A 2008 Vegetarian meat: Could technology save animals and satisfy meat eaters? J Agric Environ Ethics 21 579 596 10.1007/s10806-008-9110-0

상세보기
Hwang CM Sant S Masaeli M Kachouie NN Zamanian B Lee SH Khademhosseini A 2010 Fabrication of three-dimensional porous cell-laden hydrogel for tissue engineering Biofabrication 2 035003 10.1088/1758-5082/2/3/035003 20823504

상세보기
Joshi N Tewari K Pandey S Nautiyal P Papnai G 2020 Novel aspects, environmental impacts and future prospects of cultured meat: A review J Entomol Zool Stud 8 312 319
JUST 2018 Cultured meat: A vision of the future Available from https://www.youtube.com/watch?v=f8Ii3DB6ejE Accessed at Mar 12, 2021
Kadim IT Mahgoub O Baqir S Faye B Purchas R 2015 Cultured meat from muscle stem cells: A review of challenges and prospects J Integr Agric 14 222 233 10.1016/S2095-3119(14)60881-9

상세보기
Karunaratne JF Ashton CJ Stickland NC 2005 Fetal programming of fat and collagen in porcine skeletal muscles J Anat 207 763 768 10.1111/j.1469-7580.2005.00494.x 16367803

상세보기
Kateman B 2020 Will cultured meat soon be a common sight in supermarkets across the globe? Available from https://www.forbes.com/sites/briankateman/2020/02/17/will-cultured-meat-soon-be-a-common-sight-in-supermarkets-across-the-globe/#307f4af7c66a Accessed at Mar 12, 2021
Kim W Lee H Lee J Atala A Yoo JJ Lee SJ Kim GH 2020 Efficient myotube formation in 3D bioprinted tissue construct by biochemical and topographical cues Biomaterials 230 119632 10.1016/j.biomaterials.2019.119632 31761486

상세보기
Krieger J Park BW Lambert CR Malcuit C 2018 3D skeletal muscle fascicle engineering is improved with TGF-β1 treatment of myogenic cells and their co-culture with myofibroblasts PeerJ 6 e4939 10.7717/peerj.4939 30018850

상세보기
Kunitake R Suzuki A Ichihashi H Matsuda S Hirai O Morimoto K 1997 Fully-automated roller bottle handling system for large scale culture of mammalian cells J Biotechnol 52 289 294 10.1016/S0168-1656(96)01654-9 9084214

상세보기
Laestadius LI 2015 Public perceptions of the ethics of in-vitro meat: Determining an appropriate course of action J Agric Environ Ethics 28 991 1009 10.1007/s10806-015-9573-8

상세보기
Laestadius LI Caldwell MA 2015 Is the future of meat palatable? Perceptions of in vitro meat as evidenced by online news comments Public Health Nutr 18 2457 2467 10.1017/S1368980015000622 25818555

상세보기
Lam ATL Li J Toh JPW Sim EJH Chen AKL Chan JKY Choolani M Reuveny S Birch WR Oh SKW 2017 Biodegradable poly- ε -caprolactone microcarriers for efficient production of human mesenchymal stromal cells and secreted cytokines in batch and fed-batch bioreactors Cytotherapy 19 419 432 10.1016/j.jcyt.2016.11.009 28017598

상세보기
Laumonier T Menetrey J 2016 Muscle injuries and strategies for improving their repair J Exp Orthop 3 15 10.1186/s40634-016-0051-7 27447481

상세보기
Li C Xiong T Zhou M Wan L Xi S Liu Q Chen Y Mao H Liu S Chen B 2020 Characterization of microRNAs during embryonic skeletal muscle development in the Shan Ma Duck Animals 10 1417 10.3390/ani10081417 32823859

상세보기
Li H Zhu C Tao Z Xu W Song W Hu Y Zhu W Song C 2014 MyoD and Myf6 gene expression patterns in skeletal muscle during embryonic and posthatch development in the domestic duck ( Anas platyrhynchos domestica ) J Anim Breed Genet 131 194 201 10.1111/jbg.12057 24180358

상세보기
Li L Liu HH Xu F Si JM Jia J Wang JW 2010 MyoD expression profile and developmental differences of leg and breast muscle in Peking duck ( Anas platyrhynchos domestica ) during embryonic to neonatal stages Micron 41 847 852 10.1016/j.micron.2010.04.016 20541945

상세보기
Liu HH Wang JW Zhang RP Chen X Yu HY Jin HB Li L Han CC Xu F Kang B He H Xu HY 2012 In ovo feeding of IGF-1 to ducks influences neonatal skeletal muscle hypertrophy and muscle mass growth upon satellite cell activation J Cell Physiol 227 1465 1475 10.1002/jcp.22862 21618537

상세보기
Liu J Li L Suo H Yan M Yin J Fu JJM 2019 3D printing of biomimetic multi-layered GelMA/nHA scaffold for osteochondral defect repair Mater Des 171 107708 10.1016/j.matdes.2019.107708

상세보기
Lucas A 2019 Lab-grown meat start-up raises $14 million to build production plant Available from https://www.cnbc.com/2019/10/10/future-meat-technologies-a-lab-grown-meat-start-up-raises-14-million-dollars.html Accessed at Mar 12, 2021
MacLeod M Gerber P Mottet A Tempio G Falcucci A Opio C Vellinga T Henderson B Steinfeld H 2013 Greenhouse gas emissions from pig and chicken supply chains: A global life cycle assessment Food Agric Organ United Nations
Mancini MC Antonioli F 2020 To what extent are consumers’ perception and acceptance of alternative meat production systems affected by information? The case of cultured meat. Animals 10 656 10.3390/ani10040656 32290141

상세보기
Marga FS 2012 Engineered comestible meat National Institute of Food and Agriculture Columbia, MO, USA
Marga FS 2016 Dried food products formed from cultured muscle cells Google Patents
Matsuda R Spector DH Strohman RC 1983 Regenerating adult chicken skeletal muscle and satellite cell cultures express embryonic patterns of myosin and tropomyosin isoforms Dev Biol 100 478 488 10.1016/0012-1606(83)90240-3 6653881

상세보기
Mau M Oksbjerg N Rehfeldt C 2008 Establishment and conditions for growth and differentiation of a myoblast cell line derived from the semimembranosus muscle of newborn piglets In Vitro Cell Dev Biol Anim 44 1 5 10.1007/s11626-007-9069-6 18074188

상세보기
McCarthy JJ 2008 MicroRNA-206: The skeletal muscle-specific myomiR Biochim Biophys Acta 1779 682 691 10.1016/j.bbagrm.2008.03.001 18381085

상세보기
Melero-Martin J Al-Rubeai M 2007 In vitro expansion of chondrocytes Top Tissue Eng 3 37
Melvin RG 1995 Non point sources of pollution on rangeland U.C. Cooperative Extension Davis, CA, USA
Memphis Meats 2016a Meat culture Available from https://www.youtube.com/watch?v=DqaHWyimbQ8 Accessed at Mar 12, 2021
Memphis Meats 2016b The world’s first cell-based meatball Available from https://www.youtube.com/watch?v=Y027yLT2QY0 Accessed at Mar 12, 2021
Memphis Meats 2017 Histroic first: Cell-based poultry tasting Available from https://www.youtube.com/watch?v=b5ezRx23EMg Accessed at Mar 12, 2021
Merten OW 2015 Advances in cell culture: Anchorage dependence Philos Trans R Soc B Biol Sci 370 20140040 10.1098/rstb.2014.0040 25533097

상세보기
Metzger K Tuchscherer A Palin MF Ponsuksili S Kalbe C 2020 Establishment and validation of cell pools using primary muscle cells derived from satellite cells of pig skeletal muscle In Vitro Cell Dev Biol Anim 56 193 199 10.1007/s11626-019-00428-2 31873830

상세보기
Moritz MSM Verbruggen SEL Post MJ 2015 Alternatives for large-scale production of cultured beef: A review J Integr Agric 14 208 216 10.1016/S2095-3119(14)60889-3

상세보기
Mouat MJ Prince R 2018 Cultured meat and cowless milk: On making markets for animal-free food J Cult Econ 11 315 329 10.1080/17530350.2018.1452277

상세보기
Musarò A McCullagh K Paul A Houghton L Dobrowolny G Molinaro M Barton ER Sweeney HL Rosenthal N 2001 Localized IGF-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle Nat Genet 27 195 200 10.1038/84839 11175789

상세보기
Nienow AW Rafiq QA Coopman K Hewitt CJ 2014 A potentially scalable method for the harvesting of hMSCs from microcarriers Biochem Eng J 85 79 88 10.1016/j.bej.2014.02.005

상세보기
Perruchot MH Lefaucheur L Barreau C Casteilla L Louveau I 2013 Age-related changes in the features of porcine adult stem cells isolated from adipose tissue and skeletal muscle Am J Physiol Cell Physiol 305 C728 C738 10.1152/ajpcell.00151.2013 23864607

상세보기
Petetin L 2014 Frankenburgers, risks and approval Eur J Risk Regul 5 168 186 10.1017/S1867299X00003585

상세보기
Post MJ 2012 Cultured meat from stem cells: Challenges and prospects Meat Sci 92 297 301 10.1016/j.meatsci.2012.04.008 22543115

상세보기
Post MJ Levenberg S Kaplan DL Genovese N Fu J Bryant CJ Negowetti N Verzijden K Moutsatsou P 2020 Scientific, sustainability and regulatory challenges of cultured meat Nat Food 1 403 415 10.1038/s43016-020-0112-z

상세보기
Purdy C 2020 I’ll have the lab-grown duck pâté, please Available from https://www.newamerica.org/weekly/ill-have-the-lab-grown-duck-p%C3%A2t%C3%A9-please/ Accessed at Mar 12, 2021
Qiu H Xu X Fan B Rothschild MF Martin Y Liu B 2010 Investigation of LDHA and COPB1 as candidate genes for muscle development in the MYOD1 region of pig chromosome 2 Mol Biol Rep 37 629 636 10.1007/s11033-009-9882-y 19830590

상세보기
Rafiq QA Coopman K Hewitt CJ 2013 Scale-up of human mesenchymal stem cell culture: Current technologies and future challenges Curr Opin Chem Eng 2 8 16 10.1016/j.coche.2013.01.005

상세보기
Ridgeway AG Skerjanc IS 2001 Pax3 is essential for skeletal myogenesis and the expression of six1 and eya2 J Biol Chem 276 19033 19039 10.1074/jbc.M011491200 11262400

상세보기
Rubin LL Feodor DP 2019 Satellite cells and compositions and methods for producing the same US Patent US16/297,548
Sadler MJ 2004 Meat alternatives—market developments and health benefits Trends Food Sci Technol 15 250 260 10.1016/j.tifs.2003.09.003

상세보기
Savvides L 2019 Lab-grown meat: Taste-testing chicken of the future Available from https://www.cnet.com/news/lab-grown-cultured-clean-meat-tasting-the-chicken-of-the-future-just-inc/ Accessed at Mar 12, 2021
Schneider Z 2012 In vitro meat: Space travel, cannibalism, and federal regulation Hous L Rev 50 991
Shaffer E 2020 Memphis meats sets sights on building a pilot plant Available from https://www.meatpoultry.com/articles/22509-memphis-meats-sets-sights-on-building-a-pilot-plant Accessed at Mar 12, 2021
Shi X Garry DJ 2006 Muscle stem cells in development, regeneration, and disease Genes Dev 20 1692 1708 10.1101/gad.1419406 16818602

상세보기
Siegrist M Hartmann C 2020 Consumer acceptance of novel food technologies Nat Food 1 343 350 10.1038/s43016-020-0094-x

상세보기
Siegrist M Sütterlin B Hartmann C 2018 Perceived naturalness and evoked disgust influence acceptance of cultured meat Meat Sci 139 213 219 10.1016/j.meatsci.2018.02.007 29459297

상세보기
Southey F 2020 ‘Ethical foie-gras’: Cultured meat start-up taps duck egg cells to recreate French delicacy Available from https://www.foodnavigator.com/Article/2020/05/14/Ethical-foie-gras-Cultured-meat-start-up-taps-duck-egg-cells-to-recreate-French-delicacy Accessed at Mar 12, 2021
Stanbury PF Whitaker A Hall SJ 2013 Principles of fermentation technology 2 nd ed Elsevier Amsterdam, Nederland
Steinfeld H Gerber P Wassenaar TD Castel V Rosales M Rosales M De Haan C 2006 Livestock’s long shadow: Environmental issues and options Food and Agriculture Organization of the United Nations [FAO] Rome, Italy
Stephens N Di Silvio L Dunsford I Ellis M Glencross A Sexton A 2018 Bringing cultured meat to market: Technical, socio-political, and regulatory challenges in cellular agriculture Trends Food Sci Technol 78 155 166 10.1016/j.tifs.2018.04.010 30100674

상세보기
Stickland NC 1978 A quantitative study of muscle development in the bovine foetus ( Bos indicus ) Anat Histol Embryol 7 193 205 10.1111/j.1439-0264.1978.tb00795.x 152066

상세보기
Tavassoli H Alhosseini SN Tay A Chan PPY Weng Oh SK Warkiani ME 2018 Large-scale production of stem cells utilizing microcarriers: A biomaterials engineering perspective from academic research to commercialized products Biomaterials 181 333 346 10.1016/j.biomaterials.2018.07.016 30098569

상세보기
Tomiyama AJ Kawecki NS Rosenfeld DL Jay JA Rajagopal D Rowat AC 2020 Bridging the gap between the science of cultured meat and public perceptions Trends Food Sci Technol 104 144 152 10.1016/j.tifs.2020.07.019

상세보기
Tuomisto HL Teixeira de Mattos MJ 2011 Environmental impacts of cultured meat production Environ Sci Technol 45 6117 6123 10.1021/es200130u 21682287

상세보기
UN [United Nations] 2019 World population prospects 2019 UN New York, NY, USA
Van Der Weele C Tramper J 2014 Cultured meat: Every village its own factory? Trends Biotechnol 32 294 296 10.1016/j.tibtech.2014.04.009 24856100

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Van Wezel AL 1967 Growth of cell-strains and primary cells on micro-carriers in homogeneous culture Nature 216 64 65 10.1038/216064a0 4292963

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Verbeke W Marcu A Rutsaert P Gaspar R Seibt B Fletcher D Barnett J 2015 ‘Would you eat cultured meat?’: Consumers’ reactions and attitude formation in Belgium, Portugal and the United Kingdom Meat Sci 102 49 58 10.1016/j.meatsci.2014.11.013 25541372

상세보기
Verbruggen S Luining D Van Essen A Post MJ 2018 Bovine myoblast cell production in a microcarriers-based system Cytotechnology 70 503 512 10.1007/s10616-017-0101-8 28470539

상세보기
Welin S Van der Weele C 2012 Cultured meat: Will it separate us from nature? In Climate change and sustainable development Potthast T Meisch S (ed) Springer Berlin, Germany 348 351 10.3920/978-90-8686-753-0_52
Wesson LG Jr Cohn WE Brues AM 1949 The effect of temperature on potassium equilibria in chick embryo muscle J Gen Physiol 32 511 523 10.1085/jgp.32.4.511 18114563

상세보기
Wojtczak J 1979 Contractures and increase in internal longitudinal resistance of cow ventricular muscle induced by hypoxia Circ Res 44 88 95 10.1161/01.RES.44.1.88 758236

상세보기
Wu N Gu T Lu L Cao Z Song Q Wang Z Zhang Y Chang G Xu Q Chen G 2019 Roles of miRNA-1 and miRNA-133 in the proliferation and differentiation of myoblasts in duck skeletal muscle J Cell Physiol 234 3490 3499 10.1002/jcp.26857 30471101

상세보기
Wu Z Chen J Ren J Bao L Liao J Cui C Rao L Li H Gu Y Dai H Zhu H Teng X Cheng L Xiao L 2009 Generation of pig induced pluripotent stem cells with a drug-inducible system J Mol Cell Biol 1 46 54 10.1093/jmcb/mjp003 19502222

상세보기
Yablonka-Reuveni Z Quinn LS Nameroff M 1987 Isolation and clonal analysis of satellite cells from chicken pectoralis muscle Dev Biol 119 252 259 10.1016/0012-1606(87)90226-0 3025033

상세보기
Yamashita T Sohal GS 1986 Development of smooth and skeletal muscle cells in the iris of the domestic duck, chick and quail Cell Tissue Res 244 121 131 10.1007/BF00218389 3698083

상세보기
Zeltinger J Sherwood JK Graham DA Müeller R Griffith LG 2001 Effect of pore size and void fraction on cellular adhesion, proliferation, and matrix deposition Tissue Eng 7 557 572 10.1089/107632701753213183 11694190

상세보기
Zhu MJ Ford SP Nathanielsz PW Du M 2004 Effect of maternal nutrient restriction in sheep on the development of fetal skeletal muscle Biol Reprod 71 1968 1973 10.1095/biolreprod.104.034561 15317692

상세보기

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표제어: PCR

동의어: Packet Collision Rate

용어 설명 출처 목록 (6)

용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

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