[논문]항암화학요법 유발 말초신경병증에 대한 한방치험 1례

신혜령; 서욱철; 안성후; 원진희; 송봉근

doi:10.22246/jikm.2021.42.2.104

항암화학요법 유발 말초신경병증에 대한 한방치험 1례
Case Report of Chemotherapy-Induced Peripheral Neuropathy Treated with Korean Medicine 원문보기

대한한방내과학회지 = The journal of internal Korean medicine, v.42 no.2, 2021년, pp.104 - 113

신혜령 (원광대학교 광주한방병원 한방내과) , 서욱철 (원광대학교 광주한방병원 침구과) , 안성후 (원광대학교 광주한방병원 한방재활과) , 원진희 (원광대학교 광주한방병원 한방내과) , 송봉근 (원광대학교 광주한방병원 한방내과)

Abstract ▼ AI-Helper

Introduction: The aim of this study is to report on the effectiveness of Korean medicine to improve symptoms of chemotherapy-induced peripheral neuropathy (CIPN). Some patients are treated with medication, but medications may have no effect in some patients. Korean medicine treatments have been used in such patients, but few reports exist. Case Presentation: A 58-year-old female patient with CIPN reported symptoms of bilateral limb pain and tingling sensations as well as cold sensations in bilateral lower legs and hands, fatigue, and bilateral limb weakness. To reduce the patient's symptoms, we provided Korean medical treatment, including herbal medicine (Uchashinki-hwan), acupuncture, and moxibation. To evaluate the results of this treatment, we used a numeric rating scale (NRS), the manual muscle test (MMT), the National Cancer Institute Common Toxicity Criteria for Adverse Events (CTCAE), and the European Organization for Research and Treatment of Cancer quality-of-life questionnaire about CIPN (EORTC-QLQ-CIPN20). After 49 days of treatment, the NRS scores decreased for bilateral limb pain and tingling, for bilateral lower leg and hand cold sensation, and for fatigue. The MMT results for the upper and lower extremities were improved. CTCAE Grade and EORTC QLQ-CIPN20 score were also decreased. Conclusion: According to these results, Korean medicine treatment may be considered an effective treatment for CIPN. Prospective studies are needed in the future to confirm and expand these findings.

주제어

표/그림 (6)

표 Table 1. Composition of Per Os Medication
표 Table 2. Components of Uchashinki-hwan
그림 Fig. 1. Timeline of treatments and outcomes.
그림 Fig. 2. Changes of symptoms with NRS (numerical rating scale).
표 Table 3. NCI CTCAE Grade and EORTC QLQ CIPN 20 Score Before and After Treatment
표 Table 4. Changes of Motor Grade Measured with MMT

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