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2% 클로르헥시딘 침상목욕이 중환자실의 의료관련감염과 다제내성균 감염 발생률에 미치는 효과에 대한 체계적 문헌 고찰 및 메타분석
Effect of 2% Chlorhexidine Bathing on the Incidence of Hospital-Acquired Infection and Multidrug-Resistant Organisms in Adult Intensive Care Unit Patients: Systematic Review and Meta-Analysis 원문보기

Journal of Korean academy of nursing = 대한간호학회지, v.51 no.4, 2021년, pp.414 - 429  

서지수 (충남대학교 간호대학) ,  송라윤 (충남대학교 간호대학)

Abstract ▼ AI-Helper 아이콘AI-Helper

Purpose: This systematic review and meta-analysis analyzed the effects of 2% chlorhexidine bathing on the incidence of hospital-acquired infection (HAI) and multidrug-resistant organisms (MDRO) in adult intensive care units. Methods: PubMed, CINAHL, Cochrane library, and RISS database were systemati...

주제어

#메타분석   #클로르헥시딘   #침상목욕   #의료관련감염   #다제내성균 감염  

참고문헌 (24)

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  9. Frost SA, Alogso MC, Metcalfe L, Lynch JM, Hunt L, Sanghavi R, et al. Chlorhexidine bathing and health care-associated infections among adult intensive care patients: A systematic review and meta-analysis. Critical Care. 2016;20(1):379. https://doi.org/10.1186/s13054-016-1553-5 

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  17. Siegel JD, Rhinehart E, Jackson M, Chiarello L. Management of multidrug-resistant organisms in health care settings, 2006. American Journal of Infection Control. 2007;35(10Suppl 2):S165-S193. https://doi.org/10.1016/j.ajic.2007.10.006 

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  18. Hayden MK, Lolans K, Haffenreffer K, Avery TR, Kleinman K, Li H, et al. Chlorhexidine and mupirocin susceptibility of methicillin-resistant Staphylococcus aureus isolates in the REDUCE-MRSA trial. Journal of Clinical Microbiology. 2016;54(11):2735-2742. https://doi.org/10.1128/JCM.01444-16 

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  19. Kim NY, Ryu S, Kim YH. Effects of oral care using chlorhexidine gluconate on ventilator-associated pneumonia and mortality: A systematic review and meta-analysis. Korean Journal of Adult Nursing. 2019;31(2):109-122. https://doi.org/10.7475/kjan.2019.31.2.109 

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  20. Abbas S, Sastry S. Chlorhexidine: Patient bathing and infection prevention. Current Infectious Disease Reports. 2016;18(8):25. https://doi.org/10.1007/s11908-016-0532-y 

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  21. Kengen R, Thoonen E, Daveson K, Loong B, Rodgers H, Beckingham W, et al. Chlorhexidine washing in intensive care does not reduce bloodstream infections, blood culture contamination and drug-resistant microorganism acquisition: An interrupted time series analysis. Critical Care and Resuscitation. 2018;20(3):231-240. 

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  22. Nerandzic MM, Donskey CJ. Induced sporicidal activity of chlorhexidine against Clostridium difficile spores under altered physical and chemical conditions. PLoS One. 2015;10(4):e0123809. https://doi.org/10.1371/journal.pone.0123809 

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  23. Oh SH, Kang HY. Identification of target risk groups for population-based Clostridium difficile infection prevention strategies using a population attributable risk approach. International Journal of Infectious Diseases. 2018;66:107-112. https://doi.org/10.1016/j.ijid.2017.11.021 

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  24. Choi EY, Park DA, Kim HJ, Park J. Efficacy of chlorhexidine bathing for reducing healthcare associated bloodstream infections: A meta-analysis. Annals of Intensive Care. 2015;5(1):31. https://doi.org/10.1186/s13613-015-0073-9 

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