[논문]메탄올 작업장 노출 평가에의 EU REACH 프로토콜 적용: Targeted Risk Assessment

나진성; 송문환; 최은경

doi:10.5668/jehs.2021.47.5.432

메탄올 작업장 노출 평가에의 EU REACH 프로토콜 적용: Targeted Risk Assessment
The Application of an EU REACH Protocol to the Occupational Exposure Assessment of Methanol: Targeted Risk Assessment 원문보기

韓國環境保健學會誌 = Journal of environmental health sciences, v.47 no.5, 2021년, pp.432 - 445

나진성 (한국생산기술연구원 환경규제기술센터) , 송문환 (한국생산기술연구원 환경규제기술센터) , 최은경 (한국생산기술연구원 환경규제기술센터)

Abstract ▼ AI-Helper

Background: The European Centre for Ecotoxicology and Toxicology of Chemicals' Targeted Risk Assessment (ECETOC TRA) tool has been recognized by EU REACH as a preferred approach for calculating worker health risks from chemicals. Objectives: The applicability of the ECETOC TRA to occupational exposure estimation from industrial uses of methanol was studied by inputting surveyed and varied parameters for TRA estimation as well as through comparison with measured data. Methods: Information on uses of methanol was collected from seven working environment monitoring reports along with the measured exposure data. Input parameters for TRA estimation such as operating conditions (OCs), risk management measures (RMMs) and process categories (PROCs) were surveyed. To compare with measured exposures, parameters from the surveyed conditions of ventilation but no use of respiratory protection were applied. Results: PROCs 4, 5, 8a, 10, and 15 were assigned to ten uses of methanol. The uses include as a solvent for manufacturing sun cream, surfactants, dyestuffs, films and adhesives. Methanol was also used as a component in a release agent, hardening media and mold wash for cast products as well as a component of hard-coating solution and a viscosity-controlling agent for manufacturing glass lenses. PROC 8a and PROC 10 of a cast product manufacturer without LEV (local exhaust ventilation) and general ventilation as well as no respiratory protection resulted in the highest exposure to methanol. Assuming the identical worst OCs and RMMs for all uses, exposures from PROC 5, 8a, and 10 were the same and the highest followed by PROC 4 and 15. The estimation resulted in higher exposures in nine uses except one use where measured exposure approximated exposures without RMMs. Conclusions: The role of ECETOC TRA as a conservative exposure assessment tool was confirmed by comparison with measured data. Moreover, it can guide which RMMs should be applied for the safe use of methanol.

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표/그림 (8)

표 Table 1. Information of methanol for human health assessment and reference values^19,20)
표 Table 2. Input parameters for worker health assessment using ECETOC TRA and available selections for each parameter^2,18)
표 Table 3. Input parameters for exposure estimation of methanol in seven workplaces and resulting worker exposures Input parameters from the survey on seven workplaces
표 Table 4. Input parameters for exposure estimation of methanol in seven workplaces and resulting worker exposures Input parameters for comparison with measured exposures
그림 Fig. 1. Flow chart for worker exposure assessment of methanol and comparison of its estimated and measured exposures from various industrial uses
그림 Fig. 2. Surveyed use examples of methanol in industrial sites and the corresponding process categories and OCs/RMMs
그림 Fig. 3. Estimation of methanol exposures using ECETOC TRA (a) by inputting surveyed parameters to predict workplace exposures and (b) by assuming identical worst parameters for all uses to compare exposures of PROCs
그림 Fig. 4. Comparison of worker exposures of methanol from different process categories estimated by ECETOC TRA assuming no respiratory protection and those measured by KOSHA guide¹⁷⁾

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