[논문]나노 소재 혼입 시멘트 복합체의 급성경구독성시험 및 급성경피독성시험을 통한 유해성 평가

성재혁; 송경석; 정연웅; 정상화; 김주형

doi:10.14190/jrcr.2022.10.4.411

나노 소재 혼입 시멘트 복합체의 급성경구독성시험 및 급성경피독성시험을 통한 유해성 평가
Safety Assessments through Acute Oral Toxicity Test and Acute Dermal Toxicity Test of Cement Composite Containing Nano Materials 원문보기

Journal of the Korean Recycled Construction Resources Institute = 한국건설순환자원학회 논문집, v.10 no.4, 2022년, pp.411 - 419

성재혁 (한국건설생활환경시험연구원 환경독성센터) , 송경석 (한국건설생활환경시험연구원 바이오본부) , 정연웅 (한국건설생활환경시험연구원 건설기술연구센터) , 정상화 (한국건설생활환경시험연구원 건설본부) , 김주형 (한국건설생활환경시험연구원 건설기술연구센터)

초록
AI-Helper

본 연구에서는 탄소나노튜브를 혼입한 경량·고강도 시멘트 독합체의 유해성을 평가하기 위해 급성경구독성시험 및 급성경피 독성시험을 실시하고, 이를 재령 28일 압축강도 50 MPa 수준의 탄소나노튜브를 혼입하지 않은 일반 콘크리트의 유해성과 비교하였다. 일반 콘크리트 및 탄소나노튜브를 혼입한 경량·고강도 시멘트 복합체 모두 급성경구독성시험결과 GHS category 5인 것으로 조사되었다. 또한, 모든 시편에서 급성경피독성시험에서 독성증상은 관찰되지 않았으며, GHS category 5/미분류(unclassified)에 해당하는 것으로 판단된다.

Abstract ▼ AI-Helper

This study conducted acute oral toxicity test and acute dermal toxicity test to evaluate the toxicity of lightweight and high-strength cement composite containing carbon nanotube. It was compared with the toxicity of ordinary concrete that did not contain carbon nanotube. Both lightweight and high-strength cement composite and ordinary concrete were categorized in GHS category 5 as a result of acute oral toxicity test. In addition, no toxic symproms were observed during the acute dermal toxicity test in all specimens, concluding that those were judged to correspond to GHS category 5/unclassified.

주제어

표/그림 (9)

표 Table 1. Mix design for concrete specimen (unit: kg/m³)
그림 Fig. 1. Cummulative particle distribution of ground specimens
그림 Fig. 2. Test Procedure with a starting dose of 2000 mg/kg body weight (OECD 2001)
그림 Fig. 3. Flowchart for the testing procedure (OECD 2017)
그림 Fig. 4. Result of compressive strength test at 7 days and 28 days
그림 Fig. 5. Body weight of female rats of concrete powder in acute oral toxicity study
그림 Fig. 6. Body weights of female rats of concrete powder in acute dermal toxicity study
그림 Fig. 7. Body weights of female rats of nano-concrete composite material containing nanomaterials in acute oral toxicity study
그림 Fig. 8. Body weights of female rats of nano-concrete composite material containing nanomaterials in acute dermal toxicity study

참고문헌 (17)

Braakhuis, H.M., Park, M.V., Gosens, I., De Jong, W.H., Cassee,？F.R. (2014). Physicochemical characteristics of nanomaterials？that affect pulmonary inflammation, Particle and Fibre？Toxicology, 11, 18.

상세보기
Donaldson K., Schinwald A., Murphy, F., Cho, W.S., Duffin, R., Tran,？L., Poland, C. (2013). The biologically effective dose in inhalation？nanotoxicology, Accounts of Chemical Research, 46(3),？723-732.

상세보기
Fukushima, S., Kasai, T., Umeda, Y., Shnishi, M., Sasaki, T.,？Matsumoto, M. (2018). Carcinogenicity of multi-walled carbon？nanotubes: challenging issue on hazard assessment, Journal of？Occupational Health, 60(1), 10-30.
Im, S.M., Cho, S.M., Liu, J.X., Lim, S., Bae, S.C. (2022). Investigation？on the characteristics of interfacial transition zone(ITZ) of？high-strength cement mortar incorporating graphene oxide,？Journal of the Korean Recycled Construction Resources？Institute, 10(3), 343-350 [in Korean].
Jeong, Y., Lim, G.H., Kang, Y.H., Jung, S.H., Kim, J.H. (2020).？Preliminary study on development of high strength cement？composites at 2,000 kg/m 3 of specific weight, Journal of the？Korean Recycled Construction Resources Institute, 8(4),？562-570 [in Korean].
Kasai, T., Umeda, Y., Ohnishi, M., Mine, T., Kondo, H., Takeuchi,？T., Matsumoto, M., Fukushima, S. (2015). Lung carcinogenicity？of inhaled multi-walled carbon nanotube in rats, Particle and？Fibre Toxicology, 13(1), 1-19.
Kim, J.H., Kim, W.W., Moon, J.H., Chung, C.W. (2020). Effect of？multi-walled carbon nanotube on rheological behavior and？compressive strength of cement paste, Journal of the Korea？Recycled Construction Resources Institute, 8(4), 467-474 [in？Korean].
Kobayashi, N., Izumi, H., Morimoto, Y. (2017). Review of toxicity？studies of carbon nanotubes, Journal of Occupational Health, 59,？394-407.

상세보기
KS F 2527. (2020). Concrete Aggregate, Korean Standards？Association, Republic of Korea [in Korean].
Lee, D.K., Jeon, S., Jeong, J., Song, K.S., Cho, W.S. (2020). Carbon？nanomaterial-derived lung burden analysis using UV-Vis？spectrophotometry and proteinase K digestion, Particle and？Fibre Toxicology, 17(1), 1-11.
Ministry of Environment Notice No. 2018-23. (2018). Regulations on？Designation Standards and Management Standards of Chemical？Testing Institutions(adopted: 09 Feb. 2018), Ministry of Environment,？Republic of Korea [in Korean].
National Institute of Environmental Research Notice No. 2020-28.？(2020). Regulations on Testing Methods for Chemicals(adopted:？19 Aug. 2020), National Institute of Environmental Research,？Republic of Korea [in Korean].
National Institute of Environmental Research Notice No. 2020-46.？(2020). Regulations on Testing Methods for Chemicals(adopted:？03 Nov. 2020), National Institute of Environmental Research, Republic of Korea [in Korean].
OECD Guideline for the Testing of Chemicals No. 402. (2017). Acute？Dermal Toxicity: Fixed Dose Procedure (adopted: 9 Oct. 2017),？Organisation for Economic Co-operation and Development,？France.
OECD Guideline for the Testing of Chemicals No. 423. (2001). Acute？Toxic Class Method(adopted: 17 Dec, 2001), Organisation for？Economic Co-operation and Development, France.
Sikora P., Abd Elrahman M., Stephan D. (2018). The influence of？nanomaterials on the thermal resistance of cement-based？composites - a review, Nanomaterials, 8(7), 465.

상세보기
Singh G., Saini B., (2021). Nanomaterial in cement industry: a brief？review, Innovative Infrastructure Solutions, 7(1), 1-13.

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