[논문]구강작열감증후군 환자의 임상 특징에 따른 심박변이도 분석

이현진; 하나연; 고석재; 박재우; 김진성

doi:10.22246/jikm.2022.43.1.53

구강작열감증후군 환자의 임상 특징에 따른 심박변이도 분석
Heart Rate Variability Analysis According to Clinical Characteristics in Patients with Burning Mouth Syndrome 원문보기

대한한방내과학회지 = The journal of internal Korean medicine, v.43 no.1, 2022년, pp.53 - 67

이현진 (경희대학교 대학원 임상한의학과) , 하나연 (경희대학교한방병원 위장소화내과) , 고석재 (경희대학교 대학원 임상한의학과) , 박재우 (경희대학교 대학원 임상한의학과) , 김진성 (경희대학교 대학원 임상한의학과)

Abstract ▼ AI-Helper

Objectives: This study aimed to identify the characteristics of the heart rate variability (HRV) index in patients with burning mouth syndrome (BMS) and to evaluate the predictive value of HRV for Korean medical treatment responsiveness to tongue pain in BMS. Methods: Among BMS patients who visited the Oral Diseases Clinic of Kyung Hee University Korean Medicine Hospital from January 1, 2018, to May 31, 2021, we reviewed the clinical records of 217 women aged 50 years and over. HRV and unstimulated saliva flow rate (USFR) measurements were carried out, and all patients were asked to indicate their degree of tongue pain using the visual analog scale (VAS). The subjects were classified into subgroups according to the presence or absence of hyposalivation and VAS improvement, and each subgroup was compared using the HRV index. Logistic regression analysis was conducted to confirm whether cause-effect relationships were present between statistically significant values. Results: BMS patients had lower LF and HF than healthy people. Subgroup analysis demonstrated that there were some statistically significant differences in the HRV index according to salivation rate and degree of pain. In addition, as the LF/HF ratio increased, the pain improvement rate decreased after treatment. Conclusion: The autonomic nerve activity of BMS patients was lower than that of healthy people; however, autonomic balance was not impaired. In addition, tongue pain in BMS patients responded more favorably to Korean medical treatment when patients fell within a normal range of the LF/HF ratio, suggesting that autonomic imbalance could be used as one of the predictable factors in clinical practice.

주제어

표/그림 (9)

그림 Fig. 1. Visual analogue scale for the pain of burning mouth syndrome patient
표 Table 1. Age and Sex Distribution of 272 Patients with Burning Mouth Syndrome
표 Table 2. Comparison of SDNN, RMSSD, TP, LF, HF and LF/HF Ratio in Heart Rate Variability between Normal Group and Burning Mouth Syndrome Group
표 Table 3. Comparison of SDNN, RMSSD, TP, LF, HF and LF/HF Ratio in Heart Rate Variability between Hyposalivation Group and none-Hyposalivation Group
표 Table 4. Effect of LF and LF/HF Ratio on Unstimulated Salivary Flow Rate
표 Table 6. Effect of SDNN, RMSSD, LF and HF on Visual Analogue Scale Score
표 Table 5. Comparison of SDNN, RMSSD, TP, LF, HF and LF/HF Ratio in Heart Rate Variability between Low Visual Analogue Scale Score Group and High Visual Analogue Scale Score Group
표 Table 7. Comparison of SDNN, RMSSD, TP, LF, HF and LF/HF Ratio in Heart Rate Variability between Non-Improved Group and Improved Group
표 Table 8. Effect of LF/HF Ratio on Visual Analogue Scale Improvement

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