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고지방식이 유도 비만쥐에서 이묘산의 항비만 효과
Anti-Obesity Effects of Imyo-san on High Fat Diet Induced Obese Mice 원문보기

Journal of Korean Medicine Rehabilitation : JKMR = 한방재활의학과학회지, v.32 no.2, 2022년, pp.19 - 36  

강석범 (대구한의대학교 한의과대학 한방재활의학교실) ,  손우석 (대구한의대학교 한의과대학 한방재활의학교실) ,  김영준 (대구한의대학교 한의과대학 한방재활의학교실) ,  우창훈 (대구한의대학교 한의과대학 한방재활의학교실)

Abstract ▼ AI-Helper 아이콘AI-Helper

Objectives This study is to investigate the effects and mechanisms of Imyo-san (IMS) on the obese mice model induced by high-fat diet. Methods Antioxidative capacity was measured by in vitro method. C57BL/6 mice were randomly assigned into 5 groups (n=7). Normal group was fed general diet (Normal). ...

주제어

#Imyo-san   #Lipid metabolism disorders   #Anti-obesity agents   #Antioxidants   #Anticholesteremic agents  

참고문헌 (52)

  1. The Society of Korean Medicine Rehabilitation. Oriental rehabilitation medicine. 5th ed. Paju:Globooks. 2020:322-39. 

  2. International Association for the Study of Obesity. The asia-pacific perspective: redefining obesity and its treatment. Health Communication Australia Pty. 2000:17-20. 

  3. Ministry of Health and Welfare, Korea Disease Control and Prevention Agency. Korea health statistics 2019 [Internet] Cheongju:Korea Disease Control and Prevention Agency; 2020 [updated 2020 Dec 31; cited 2021 Nov 30]. Available from: URL: https://knhanes.kdca.go.kr/knhanes/sub04/sub04_04_01.do. 

  4. Nilsson PM, Tuomilehto J, Ryden L. The metabolic syn drome - what is it and how should it be managed? Eur J Prev Cardiol. 2019;26(2_suppl):33-46. 

  5. Park EO. The obesity and the metabolic syndrome among Korean adults: based on national representative survey. Korean J Health Promot. 2020;20(4):144-50. 

    상세보기

  6. Kim MK, Kim CS. Recent advances in anti-obesity agents. Korean J Med. 2018;93(6):501-8. 

    상세보기

  7. Heo J. Treasured mirror of eastern medicine miscellaneous disorders I. Seoul:Yeogang. 1994:1308-12. 

  8. Jung YJ, Li SH. The effects of Er-miao-San extract on cell proliferation in normal human dermal fibroblasts. Asian J Beauty Cosmetol. 2013;11(5):943-9. 

  9. Chen G, Li KK, Fung CH, Liu CL, Wong HL, Leung PC, Ko CH. Er-Miao-San, a traditional herbal formula containing Rhizoma Atractylodis and Cortex Phellodendri inhibits inflammatory mediators in LPS-stimulated RAW264.7 macrophages through inhibition of NF-κB pathway and MAPKs activation. J Ethnopharmacol. 2014;154(3):711-8. 

  10. Dai X, Ding M, Zhang W, Xuan Z, Liang J, Yang D, Zhang Q, Su B, Zhu H, Jia X. Anti-inflammatory effects of different elution fractions of Er-Miao-San on acute inflammation induced by carrageenan in rat paw tissue. Med Sci Monit. 2019;25(1):7958-65. 

  11. Kim SM, Yu n HJ, Lee HW, Kim PJ, Lee CH, Park WH, Park SD. Imyosan induces caspases-mediated apoptosis in human colorectal cancer HCT116 cells. Herb Formula Sci. 2006;14(2):21-32. 

  12. Yun HJ, Heo SK, Yi HS, Kim TH, Kim DW, Kim SM, Park SD. Anti-atherosclerosis effect of Imyosan extract in human aortic smooth muscle cells. Kor J Herbology. 2008;23(4):113-20. 

  13. Dai X, Yang D, Bao J, Zhang Q, Ding J, Liu M, Ding M, Liu M, Liang J, Jia X. Er Miao San, a traditional Chinese herbal formula, attenuates complete Freund's adjuvant-induced arthritis in rats by regulating Th17/Treg cells. Pharm Biol. 2020;58(1):157-64. 

    상세보기

  14. Ahn HB, Kim SJ, Seo IB, Jeong SH. Effects of Imyo-san treatment on the monosodium iodoacetate-induced osteoarthritis in rats. J Oriental Rehab Med. 2010;20(3):13-26. 

  15. Lim YH, Kook YB. The comparison between single and Yimyosan in acute pancreatitis: Atractylodes chinensis (AC) and Phellodendron amurense Ruprecht (PAR). Herb Formula Sci. 2011;19(2):23-38. 

  16. Jang GW, Choi SI, Han X, Men X, Kwon HY, Choi YE, Park BW, Kim JJ, Lee OH. Development and validation of analytical method and antioxidant effect for berberine and palmatine in P.amurense. Journal of Food Hygiene and Safety. 2020;35(6):544-51. 

  17. Jang GW, Choi SI, Han X, Men X, Kwon HY, Choi YE, Kang NY, Park BW, Kim JJ, Lee OH. Antioxidant and anti-inflammatory activities of Phellodendron amurense extract fermented with Lactobacillus plantarum CM. Journal of Food Hygiene and Safety. 2021;36(2):196-203. 

  18. Oh YS, Kwon YS, Jung BD. Anti-inflammatory effects of the natural compounds cortex Phellodendri and Humulus japonicus on pelvic inflammatory disease in mice. Int J Med Sci. 2017;14(8):729-34. 

  19. Kim OK. Antidiabetic effect of ethanol extract on Phelladindron amurense Rupr. Journal of the Korean Applied Science and Technology. 2020;37(4):682-7. 

  20. Kim SH, Shin EJ, Hyun CK. Enhancing effect of extracts of Phellodendri Cortex on glucose uptake in normal and insulin-resistant 3T3-L1 adipocytes. Kor J Pharmacogn. 2005;36(4):291-8. 

  21. Kim KH, Ahn SC, Lee MS, Kweon OS, Oh WK, Kim MS, Sohn CB, Ahn JS. Adipocyte differentiation inhibitor isolated from the barks of Phellodendron amurense. Korean J Food Sci Technol. 2003;35(3):503-9. 

  22. Ma YH, Kim HJ, Han YH, Kim HO, Oh JS. Effects of Cortex Phellodendri on the metabolic function in experimental mouse model of obesity. J Int Korean Med. 2015;36(4):447-57. 

  23. Han HK, Choi EY. Effects of Atractylodes lancea on antioxidant enzyme activities in the liver cytosol of diabetic rats. Culinary Science & Hospitality Research. 2020;26(11):109-17. 

  24. Park YJ, Seo MG, Cominguez DC, Han IS, An HJ. Atractylodes chinensis water extract ameliorates obesity via promotion of the SIRT1/AMPK expression in high-fat diet-induced obese mice. Nutrients. 2021;13(9):2992. 

    상세보기

  25. Lee DH, Han JM, Yang WM. The effects of Atractylodes japonica Koidz. on type 2 diabetic rats. J Korean Med. 2015;36(1):75-85. 

  26. Han HK, Choi EY. Effects of Atractylodes lancea on plasma glucose and lipid profile in streptozotocin induced diabetic rats. Korean J Food Nutr. 2020;33(5):544-50. 

  27. Zhu ZH. The heart & essence of Dan-xi's methods of treatment. Beijing:China Bookstore Publishing. 1986:264. 

  28. Hatano T, Edamatsu R, Hiramatsu M, Mori A, Fujita Y, Yasuhara T. Effects of the interaction of tannins with co-existing substances. VI. Effects if tannins and related polyphenols on superoxide anion radical, and 1,1-diphenyl-2-picrylhydrazyl radical. Chem Pharm Bull. 1989;37(8):2016-21. 

  29. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biology and Medicine. 1999;26(9-10):1231-7. 

  30. Folin O, Ciocalteu V. Tyrosine and tryptophane determinations in proteins. J Biol Chem. 1927;73(2):627-50. 

  31. Jiao H, Wang SY. Correlation of antioxidant capacities to oxygen radical scavenging enzyme activities in blackberry. J Agric Food Chem. 2000;48(11):5672-76. 

    상세보기

  32. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical Chemistry. 1972;18(6):499-502. 

    상세보기

  33. Korean Endocrine Society, Korean Society for the Study of Obesity. Management of obesity, 2010 recommendation. Endocrinol Metab. 2010;25(4):301-4. 

  34. Ma C, Avenell A, Bolland M, Hudson J, Stewart F, Robertson C, Sharma P, Fraser C, MacLennan G. Effects of weight loss interventions for adults who are obese on mortality, cardiovascular disease, and cancer: systematic review and meta-analysis. BMJ. 2017;359:j4849. 

    상세보기

  35. Choi JM, Kim CB. Obesity management and scientific evidence. J Korean Med Assoc. 2011;54(3):250-65. 

  36. Kim BY, Kang SM, Kang JH, Kang SY, Kim KK, Kim KB, Kim BT, Kim SJ, Kim YH, Kim JH, Kim JH, Kim EM, Nam GE, Park JY, Son JW, Shin YA, Shin HJ, Oh TJ, Lee H, Jeon EJ, Chu ng SC, Hong YH, Kim CH. 2020 Korean society for the study of obesity guidelines for the management of obesity in Korea. J Obes Metab Syndr. 2021;30(2):81-92. 

    상세보기

  37. Korea Institute of Oriental Medicine. Obesity: Korean medicine clinical practice guideline. Seoul:Elsevier Korea L.L.C. 2016:58-81. 

  38. Herbal Formulations Text Compilation Committee. Herbal formula science in Korean medicine. Paju:Koonja publishers. 2020:1240-8. 

  39. Choi WS, Lee GS, Song WH, Koh JT, Yang JY, Kwak JS, Kim HE, Kim SK, Son YO, Nam HJ, Jin IJ, Park ZY, Kim JY, Park IY, Hong JI, Kim HA, Chu n CH, Ryu JH, Chun JS. The CH25H-CYP7B1-RORα axis of cholesterol metabolism regulates osteoarthritis. Nature. 2019;566(7743):254-8. 

  40. Kim MJ, Park EJ. Feature analysis of different In Vitro antioxidant capacity assays and their application to fruit and vegetable samples. J Korean Soc Food Sci Nutr. 2011;40(7):1053-62. 

  41. Kedare SB, Singh RP. Genesis and development of DPPH method of antioxidant assay. J Food Sci Technol. 2011;48(4):412-22. 

    상세보기

  42. Lee SM, You YH, Kim KM, Park JJ, Jeong CS, Jhon DY, Jun WJ. Antioxidant activities of native gwangyang Rubus coreanus miq. J Korean Soc Food Sci Nutr. 2012;41(3):327-32. 

  43. Abbas M, Saeed F, Anjum FM, Afzaal M, Tufail T, Bashir MS, Ishtiaq A, Hussain S, Suleria HAR. Natural polyphenols: an overview. International Journal of Food Properties. 2017;20(8):1689-99. 

    상세보기

  44. Lee YR, Yoon NR. Anti-oxidative and anti-diabetic effects of methanol extracts from medicinal plants. J Korean Soc Food Sci Nutr. 2015;44(5):681-6. 

  45. Semwal RB, Semwal DK, Vermaak I, Viljoen A. A comprehensive scientific overview of Garcinia cambogia. Fitoterapia. 2015;102:134-48. 

    상세보기

  46. Su llivan AC, Hamilton JG, Miller ON, Wheatley VR. Inhibition of lipogenesis in rat liver by (-)-hydroxycitrate. Arch Biochem Biophys. 1972;150(1):183-90. 

    상세보기

  47. Committee of Clinical Practice Guideline of the Korean Society of Lipid and Atherosclerosis. Korean guidelines for the management of dyslipidemia. 4th ed. Anyang:Academya. 2018:31-41. 

  48. Kersten S. Mechanisms of nutritional and hormonal regulation of lipogenesis. EMBO Reports. 2001;2(4):282-6. 

    상세보기

  49. Ikonen E. Cellular cholesterol trafficking and compartmentalization. Nat Rev Mol Cell Biol. 2008;9(2):125-38. 

    상세보기

  50. Ha JH, Lee SH. Role of AMPK in the regulation of cellular energy metabolism. Endocrinol Metab. 2010;25(1):9-17. 

  51. Houten SM, Violante S, Ventura FV, Wanders RJA. The biochemistry and physiology of mitochondrial fatty acid β-oxidation and its genetic disorders. Annu Rev Physio. 2016;78:23-44. 

  52. Liang H, Ward WF. PGC-1α: a key regulator of energy metabolism. Adv Physiol Educ. 2006;30(4):145-51. 

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