[논문]조위승기탕으로 호전된 암 환자의 마약성 진통제로 인한 변비 치험 1례

윤지현; 박수빈; 김은혜; 이지영; 윤성우

doi:10.22246/jikm.2022.43.2.229

[국내논문] 조위승기탕으로 호전된 암 환자의 마약성 진통제로 인한 변비 치험 1례
A Case Report on Opioid-Induced Constipation in a Patient with Cancer Treated by Jowiseunggi-tang 원문보기

대한한방내과학회지 = The journal of internal Korean medicine, v.43 no.2, 2022년, pp.229 - 236

윤지현 (강동경희대학교한방병원 한방내과) , 박수빈 (강동경희대학교한방병원 한방내과) , 김은혜 (강동경희대학교한방병원 한방내과) , 이지영 (자생의료재단 척추관절연구소) , 윤성우 (강동경희대학교한방병원 한방내과)

Abstract ▼ AI-Helper

Objective: Jowiseunggi-tang (JWSGT) is a traditional herbal medicine commonly used for purgative activity in constipation. This study evaluates JWSGT for the treatment of opioid-induced constipation (OIC), the most common and debilitating gastrointestinal effect of opioid use. Methods: A 64-year-old man with floor of mouth cancer was hospitalized for OIC, and JWSGT was administered orally twice a day for 10 days, along with acupuncture, moxibustion, and cupping. The primary outcome measures were defecation type according to the Bristol Stool Form Scale (BSFS) and the frequency of bowel movements. The Brief Fatigue Inventory (BFI) and the Functional Assessment of Cancer Therapy-General (FACT-G) were used as secondary measures. Results: After three days of JWSGT administration, spontaneous bowel movements were observed two to three times per week with improved BSFS from type 2 to 4. A reduction in BFI score (8.7 to 2.0) and an increase in FACT-G score (44.3 to 59.0) suggested an improvement in fatigue level and quality of life. Conclusion: This is the first report to assess the efficacy of JWSGT for the management of OIC in patients with cancer, and JWSGT may be an effective option to improve symptoms and quality of life in this group.

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표/그림 (4)

표 Table 1. The Composition of Jowiseunggi-tang Extract Granules
표 Table 2. Bristol Stool Form Scale
그림 Fig. 1. Progress of clinical symptoms. JWSGT : Jowiseunggi-tang
그림 Fig. 2. Changes in the brief fatigue inventory (BFI) and the functional assessment of cancer therapy-general (FACT-G).

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