[논문]네트워크 분석을 통한 동의보감(東醫寶鑑) 내상(內傷)문과 허로(虛勞)문의 처방 구성 본초 비교

곽건신; 고흥; 신선미

doi:10.22246/jikm.2023.44.1.35

[국내논문] 네트워크 분석을 통한 동의보감(東醫寶鑑) 내상(內傷)문과 허로(虛勞)문의 처방 구성 본초 비교
Comparison of Herbs in Prescription Composition of Consumptive Disease and Internal Injury in Donguibogam Through Network Analysis 원문보기

대한한방내과학회지 = The journal of internal Korean medicine, v.44 no.1, 2023년, pp.35 - 52

곽건신 (맥한의원) , 고흥 (세명대학교 한의과대학 내과학교실) , 신선미 (세명대학교 한의과대학 내과학교실)

Abstract ▼ AI-Helper

Objective: Internal injuries and consumptive disease have different causes, yet they can affect each other. The relationship and combination of prescription drugs in the clinical practice of internal injuries and consumptive disease were analyzed for various diseases of "Donguibogam" through network analysis. Methods: The prescriptions used in consumptive disease and internal injury were established by conducting a full survey on the papers extracted from Donguibogam. The R version 4.0.3 (2020-10-10) and the igraph and arules package were used to perform network analysis and association rule relationship mining analysis in the first and second prescription compositions. Results: The herb frequently used for internal injury was Glycyrrhizae Radix, while the herb combination frequently used was Citri Pericarpium-Glycyrrhizae Radix. For centrality, the main factor was generally Glycyrrhizae Radix. In the case of consumptive disease, the herb most frequently used was Angelicae Gigantis Radix, and the combination most frequently used was Rehmanniae Radix Preparata-Angelicae Gigantis Radix. In terms of centrality, it was Angelicae Gigantis Radix. As a result of the network analysis of herbal prescription frequency, each group was divided into three. Conclusion: The interrelationship between internal injury and consumptive disease prescription drugs may reveal the differences and similarities between internal injury and consumptive disease and may serve as a basis for the development of new drugs or materials that can enhance mutual effectiveness in the treatment of internal injury and consumptive diseases.

주제어

표/그림 (11)

표 Table 1. Frequency on Medicinal Materials in Korean Medicine for Consumptive Disease
표 Table 2. Frequency on Medicinal Materials in Korean Medicine for Internal Injury
표 Table 3. Frequency on Herbal Combinations in Korean Medicine for Consumptive Disease and Internal Injury
표 Table 4. Connectivity Centrality Analysis in Herbs used in Korean Medicine for Consumptive Disease and Internal Injury
표 Table 5. Top 30 of Closeness Centrality Analysis in Herbs used in Korean Medicine for Osteoporosis Consumptive Disease and Internal Injury
표 Table 6. Top 30 of Degree Betweenness Centrality Analysis in Herbs used in Korean Medicine for Consuptive Disease and Internal Injury
표 Table 7. Top 30 of Degree Eigenvector Centrality Analysis in Herbs used in Korean Medicine for Consumptive Disease and Internal Injury
그림 Fig. 1. Network diagram for herbs used in Korean medicine for consumptive disease.
표 Table 8. The Groups of Network Analysis for Herbs used in Korean Medicine for Consumptive Disease¹⁰
그림 Fig. 2. Network diagram for herbs used in Korean medicine for Internal injury.
표 Table 9. The Groups of Network Analysis for Herbs used in Korean Medicine for Internal Injury¹⁰

참고문헌 (24)

Kim HK, Lee JS, Eom GH, Lee SY, Kim SY,？Hur WY, et al. Correlation Study between Fetigue？Degree and Comprehensive Diagnosis of Qui？Xui Shui in Patients with Functional Dyspepsia.？The Journal of Korean Oriental Internal Medicine？2006;27(2):510-20.
Ministry of Health and Welfare. Announcement？of the results of the 2021. Seoul: Ministry of？Health and Welfare; 2022, p. 4.
Encyclopedia of Oriental Medicine, Editorial Board.？Encyclopedia of Oriental Medicine 12 volumes.？Seoul: Kyung Hee University Press; 1999, p. 608.
National University of Korean Medicine, Department？of Hepatology and Internal Medicine, Co-authored？with Professor. Hepatobiliary Internal Medicine.？Seoul: Oriental Medical Research Institute; 2001,？p. 685.
Yoon TD, Park YJ, Lee SC, Park YB, Oh HS.？Development of Questionnaires for Pathogenesis？Analysis of Bojungikgitang Symptom. Journal of？the Korean Society of Diagnostic Medicine 2007;11(2):45-58.
Standard Korean Medicine Terminology2.1 https://cis.kiom.re.kr/terminology/search.do 2021.
Kim JH, Kim JU, Kim KH. Review of Research？Topics on Consumptive Disease and Chronic？Fatigue. Korean Journal of Oriental Physiology？& Pathology 2013;27(5):587-92.
Shin SM, Ko H. Network Analysis of Herbs？that are Frequently Prescribed for Osteoporosis？with a Focus on Oasis Platform Research. J？Int Korean Med 2021;42(4):628-44.
Baik YS. A Study on the Concept Formation？Neishangzabing. J Korean Medical Classics 2015;28(4):179-92.
Kang BS, Ko UC, Kook YB, Kim KY, Kim？SH, Kim IR, et al. Bonchohak Seoul: Youngimsa;？1991, p. 5-682.
Jeong YK, Kim HS, Kim HH, Park YJ, Park？YB. Exploratory Structural Analysis on Eigth？Positions for New Formulations in Jingyuequanshu？by Network Analysis. J Korean Med 2014;35(3):49-59.
Heo J, protagonist Won JH. Jeong Hyo Donguibogam.？Seoul: Shinwoo Culture History; 2008, p. 243,？313-6, 411, 578.
Jeng UM. Comparative Study on Efficacy of Atractylodes Rhizome Recorded in Traditional？Medical Literature and in Recent Pharmacological？Article. Korean Herb Med Inf 2015;3(2):1-16.
Tsai YF, Chen YR, Chen JP, Tang Y, Yang？KC. Effectof hesperidin on anti-inflammation？and cellularantioxidant capacity in hydrogen？peroxide-stimulatedhuman articular chondrocytes.？Process Biochem 2019;85:175-84.

상세보기
Nanjing Pharmaceutical University Chinese Herbal？Medicine Writing Group. Chinese Herbal Medicine？(Second Volume). Nanjing: Jiangsurenminchubanshe;？1976, p. 525.
Joo YS. Ungok Herbology. Vol 2. Jeonju: Wooseok;？2013, p. 710, 1030, 1257, 1305-13.
Choi KT, Yang DC. Pharmacological Effects？and Medicinal Components of Korean Ginseng.？The Korean Ginseng Research and Industry？2012;6(2):2-21.
Department of Nephrology and internal Medicine,？Korean medicine University. Nephrology. Seoul:？Gunja Publishing House; 2015, p. 62.
Lee JH, Kim BS. Review On Concept and Clinical？Applicaion Of Yin-Deficiency Blood-Deficiency？in Donguibogam. J Physiol & Pathol Korean？Med 2018;32(5):299-304.
Chang L. Review article:epidemiology and quality？of life in Functional gastrointestinal disorders.？Aliment Pharmacol Ther 2004;20(supple 7):31-9.
Wilhelmsen I. Somatization, sensitization, and？functional dyspepsia. Scand J Psychol 2002;43(2):177-80.

상세보기
Yeo HS, Im JJ, Park HT. An Analysis of？HRV Spectrum for Observing ANS Variations？Caused by Sympathectomy and Vagotomy.？Anat Biol Anthropol 1999;12(2):289-96.
Kim JM, Lee SH, Choi WS, Ock SM, Kim CM,？Jeong KS, et al. The Relationship between？Autonomous Function and Fatigue Rating in？Patients with Fatigue. Korean Journal of Family？Medicine 2004;25(1):52-8.
Kim SH, Yoon SH. Correlation Between HRV？And Bowel Sound Parameters in The Evaluation？of Gastrointestinal Parasympathetic Nerve Activity？from Patients with Functional Dyspepsia. Korean？J Orient Int Med 2009;30(1):173-80.

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