$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

추출용매에 따른 쇠미역과 다시마의 항산화, 항노화 활성과 페놀화합물 비교분석
Comparative Analysis of Antioxidant, Anti Aging and Phenolic Compounds of Different Solvent Extracts from Saccharina japonica and Costaria costata 원문보기

韓國資源植物學會誌 = Korean journal of plant resources, v.36 no.2, 2023년, pp.107 - 121  

이현화 (조선대학교 생명과학과) ,  김진솔 (조선대학교 생명과학과) ,  정준한 (조선대학교 생명과학과) ,  김춘성 (조선대학교 구강생화학교실) ,  이숙영 (조선대학교 해양생물연구교육센터)

초록
AI-Helper 아이콘AI-Helper

본 연구에서는 추출용매에 완도산 다시마와 쇠미역의 항산화, 항노화 활성을 살펴보고 페놀화합물 함량을 비교 분석하였다. 먼저 다시마와 쇠미역 추출물의 폴리페놀, 플라보노이드 함량은 각각 다시마 메탄올추출물(4.64 mgTAN/g), 쇠미역 메탄올추출물(4.19 mgQUE/g)이 다른 추출물에 비해 높은 함량을 보였다. 또한 다시마와 쇠미역의 DPPH 라디칼 소거능은 모두 열수 추출물에서 가장 낮은 활성을 보였으며 쇠미역 주정추출물에서 높은 DPPH 라디칼 소거능(IC50 = 42.5 ㎍/µL)을 나타냈다. ABTS 라디칼 소거능FRAP 활성 측정 결과 다시마와 쇠미역 모두 열수보다 주정과 메탄올 추출물에서 높은 활성을 보였으며, 특히 쇠미역이 다시마보다 높은 ABTS 라디칼 소거능과 FRAP 활성을 나타냈다. 또한 다시마와 쇠미역 추출물의 SOD, CAT, APX 활성은 열수, 주정 추출물보다 메탄올 추출물에서, 그리고 쇠미역보다 다시마에서 높은 SOD, CAT, APX 활성이 확인되어 다시마 메탄올 추출물에서 뛰어난 항산화 효소 활성을 보였다. 그 다음으로 Collagenase, elastase 저해 활성은 쇠미역 메탄올 추출물과 다시마 주정추출물에서 각각 88.3, 19.0%의 우수한 collagenase 및 elastase 저해활성을 보였다. 미백 효과를 평가하기 위해 tyrosinase 저해 활성을 측정한 결과에서는 다시마와 쇠미역 모두 메탄올 추출물에서 각각 41.8, 30.3%로 나타나 다른 추출용매에 비해 높은 tyrosinase 저해활성이 측정되었으며, 주로 쇠미역보다 다시마에서 우수한 tyrosinase저해활성이 관찰되었다. 마지막으로 추출용매에 따른 다시마와 쇠미역 추출물의 페놀화합물 함량(4-hydroxybenzoic acid, naringenin, naringin, nicotinic acid) 분석 결과 4-hydroxybenzoic acid 함량은 다시마 메탄올 추출물(8.25 ㎍/g), naringenin과 naringin 함량은 각각 쇠미역 주정추출물(0.58 ㎍/g), 다시마 주정추출물(661.66 ㎍/g), 마지막으로 nicotinic acid 함량은 쇠미역 주정 추출물에서 18.06 ㎍/g으로 가장 높은 함량이 측정되었다. 본 실험 결과 다시마와 쇠미역은 메탄올과 주정 추출물에서 열수 추출물에 비해 높은 폴리페놀 함량, 항산화 및 항노화 활성과 naringenin, naringin, nicotinic acid 함량이 나타났으며, 다시마와 쇠미역에 포함된 다양한 폴리페놀과 플라보노이드 물질이 다시마와 쇠미역의 항산화활성에 관여한 것으로 확인되어 다시마와 쇠미역 주정 및 메탄올 추출물의 추출조건을 확립할 수 있었고, 이를 이용한 건강 기능성 식품 소재로 활용과 화장품 소재개발에 대한 가능성이 증가 될 수 있을 것으로 판단된다.

Abstract AI-Helper 아이콘AI-Helper

This study analyzed the polyphenol, flavonoid contents, antioxidant activity, anti-aging activity and phenol component contents of Saccharina japonica (SJ), Costaria costata (CC) extracts with hot water, 95% methanol, 95% prethanol for investigating possible utilization of SJ and CC extracts. The re...

주제어

표/그림 (7)

참고문헌 (69)

  1. Aebi, H. 1984. Catalase in vitro. Methods Enzymol. 105:121-126.? 

  2. Aguilera, J., A. Dummermuth, U. Karsten, R. Schriek and C.?Wiencke. 2002. Enzymatic defences against photooxidative?stress induced by ultraviolet radiation in arctic marine macroalgae. Polar Biol. 25(6):432-441.? 

  3. Al-Hazzani, A.A. and A.A. Alshatwi. 2011. Catechin hydrate?inhibits proliferation and mediates apoptosis of SiHa human?cervical cancer cells. Food. Chem. Toxicol. 49(12):3281-3286.? 

  4. Aminina, N., T. Vishnevskaya, E. Karaulova, N. Epur and E.?Yakush. 2020a. Prospects for the use of commercial and potentially commercial brown algae of the far eastern seas as?a source of polyphenols. Russ. J. Mar. Biol. 46(1):34-41.? 

  5. Aminina, N.M., E.P. Karaulova, T.I. Vishnevskaya, E.V. Yakush,?Y.K. Kim, K.H. Nam and K.T. Son. 2020b. Characteristics?of polyphenolic content in brown algae of the pacific coast of?russia. Molecules 25(17):3909.? 

  6. Andrade, J.E. and J.R. Burgess. 2007. Effect of the citrus flavanone naringenin on oxidative stress in rats. J. Agr. Food. Chem.?55(6):2142-2148.? 

  7. Baek, S.H., H.J. Lee, C.H. Lee, T.J. Nam and S.G. Lee. 2019.?Change of fucoxanthin and total antioxidant capacities of?Saccharina japonica during the drying process. Korean J.?Food Sci. Technol. 51(6):524-530.? 

  8. Bangmei, X. and I.A. Abbott. 1987. Edible seaweeds of china?and their place in the chinese diet. Eco. Bot. 41(3):341-353.? 

  9. Baweja, P. and D. Sahoo. 2015. Classification of Algae. In Sahoo,?D. and J. Seckbach (eds.), The Algae World, Springer, Dordrecht, Netherlands. pp. 31-55.? 

  10. Beauchamp, C. and I. Fridovich. 1971. Superoxide dismutase:?improved assays and an assay applicable to acrylamide gels.?Anal. Biochem. 44(1):276-287.? 

  11. Ben Abdallah Kolsi, R., A. Ben Gara, R. Chaaben, A. El Feki,?F. Paolo Patti, L. El Feki and K. Belghith. 2015. Anti-obesity?and lipid lowering effects of Cymodocea nodosa sulphated?polysaccharide on high cholesterol-fed-rats. Arch. Physiol.?Biochem. 121(5):210-217.? 

  12. Bischof, K. and R. Rautenberger. 2012. Seaweed Responses to?Environmental Stress: Reactive Oxygen and Antioxidative?Strategies. In: Wiencke, C. and K. Bischof (eds.), Springer,?Heidelberg, Berlin, Germany, pp. 109-132.? 

  13. Blois, M.S. 1958. Antioxidant determinations by the use of a?stable free radical. Nature 181(4617):1199-1200.? 

  14. Cannell, R.J., S.J. Kellam, A.M. Owsianka and J.M. Walker.?1988. Results of a large scale screen of microalgae for the?production of protease inhibitors. J. Med. Plants Res. 54(01):10-14.? 

  15. Castejo?n, N., K.A. Thorarinsdottir, R. Einarsdottir, K. Kristbergsson and G. Marteinsdottir. 2021. Exploring the potential?of icelandic seaweeds extracts produced by aqueous pulsed?electric fields-assisted extraction for cosmetic applications.?Mar. Drugs. 19(12):662.? 

  16. Choi, Y.S., J.H. Choi, D.J. Han, H.Y. Kim, H.W. Kim, M.A.?Lee, H.J. Chung and C.J. Kim. 2012. Effects of Laminaria?japonica on the physico-chemical and sensory characteristics?of reduced-fat pork patties. Meat. Sci. 91(1):1-7.? 

  17. Cornish, M.L. and D.J. Garbary. 2010. Antioxidants from macroalgae: potential applications in human health and nutrition.?Algae 25(4):155-171.? 

  18. Dang, T.T., M.C. Bowyer, I.A. Van Altena and C.J. Scarlett. 2018. Comparison of chemical profile and antioxidant properties of the brown algae. Int. J. Food Sci. Tech. 53(1):174-181.? 

  19. Delaney, A., K. Frangoudes and S.A. Ii. 2016. Society and?Seaweed: Understanding the Past and Present. Academic?Press, MA (USA). pp. 7-40.? 

  20. Dinh, T.V., P.S. Saravana, H.C. Woo and B.S. Chun. 2018.?Ionic liquid-assisted subcritical water enhances the extraction?of phenolics from brown seaweed and its antioxidant activity.?Sep. Purif. Technol. 196:287-299.? 

  21. FAO. 2020. The State of World Fisheries and Aquaculture?2020 (Sustainability in Action). Rome, Italy. p. 32.? 

  22. Farvin, K.S. and C. Jacobsen. 2013. Phenolic compounds and?antioxidant activities of selected species of seaweeds from?Danish coast. Food. Chemistry 138(2-3):1670-1681.? 

  23. Fatma, C., O. Yilmaz, F. Durucan and N.S. Ozdemir. 2015.?Biochemical components of three marine macroalgae (Padina?pavonica, Ulva lactuca and Taonia atomaria) from the?levantine sea coast of antalya, Turkey. J. Biol. Env. Sci. 6:?401-411.? 

  24. Folin, O. and W. Denis. 1912. On phosphor-tungstic-phosphomolybdic compounds as color reagents. J. Biol. Chem. 12(2):239-243.? 

  25. Ganesan, A.R., U. Tiwari and G. Rajauria. 2019. Seaweed?nutraceuticals and their therapeutic role in disease prevention.?Food Sci. Hum. Wellness 8(3):252-263.? 

  26. Gehring, W. 2004. Nicotinic acid/niacinamide and the skin. J.?Cosmet. Dermatol. 3(2):88-93.? 

  27. Guo, L., A. Tuyama, C. Butkinaree, K. Chung, M.D. O'Donnell,?E. Montenont and E.A. Fisher. 2013. Niacin (vitamin B3,?nicotinic acid) decreases VLDLA-polipoprotein B secretion?and reduces hepatic and blood lipid concentrations: roles of?niacin metabolism and autophagy degradation. FASEB. J.?27(S1):361.1-361.4.? 

  28. Haijin, M., J. Xiaolu and G. Huashi. 2003. A κ-carrageenan?derived oligosaccharide prepared by enzymatic degradation?containing anti-tumor activity. J. Appl. Phycol. 15(4):297-303.? 

  29. Hwang, H.J., S.Y. Lee, S.M. Kim and S.B. Lee. 2011. Fermentation of seaweed sugars by Lactobacillus species and the?potential of seaweed as a biomass feedstock. Biotechnol.?Bioprocess Eng. 16(6):1231-1239.? 

  30. Hwang, J.Y., J.S. Jang, D.G. Ryu, K.T. Kim, M.K. Huh and?S.H. Eom. 2019. Quality characteristics of the myungranjeot with Saccharina japonica water extract fermented by?lactic acid bacteria. Korean J. Fish. Aquat Sci. 52(3):193-198?(in Korean).? 

  31. Ibraheem, I.B.M., N. Abdel-Raouf, H.M. Mohamed, R. Fassihy?and S. Hamed. 2017. Impact of the microbial suppression by?using the brown alga Dictyota dichotoma extract. Egypt. J.?Bot. 57(7th International Conf.):205-214.? 

  32. Jeong, Y.U. and Y.J. Park. 2018. Studies on Antioxidant, Anti-Inflammation and collagenase inhibitory effects of extracts?from plants of the Salix genus. J. Soc. Cosmet. Scientists?Korea 44(3):335-341 (in Korean).? 

  33. Kang, S.Y., E. Kim, I. Kang, M. Lee and Y. Lee. 2018. Antidiabetic effects and anti-inflammatory effects of Laminaria?japonica and Hizikia fusiforme in skeletal muscle: in vitro?and in vivo model. Nutrients 10(4):491.? 

  34. Kim, H.J., S.I. Kim and Y.S. Han. 2008. Effects of sea tangle?extract and sea tangle yogurt on constipation relief. Korean J.?Food. Cook. Science 24(1):59-67 (in Korean).? 

  35. Kim, J.H., D.S. Lee, C.W. Lim, H.Y. Park and J.H. Park. 2002.?Antibacterial activity of sea-mustard, Laminaria japonica?extracts on the cariogenic bacteria, Streptococcus mutans.?Korean J. Fish. Aquat Sci. 35(2):191-195 (in Korean).? 

  36. Kim, K.A., T.H. Oh and S.H. Chun. 2021. Antioxidative activities?and protective effects on alcohol-induced oxidative stress in?the human hepatic HepG2 cells of Undaria pinnatifida and?Costaria costata extracts. J. Mar. Life Sci. 6(2):66-72 (in?Korean).? 

  37. Kim, M. and S. Park. 2019. Antioxidant and anti-bacterial effect?of Costaria Costata (C. Agardh) Saunders extracts. Korean?J. Community Living Sci. 30(4):509-516 (in Korean).? 

  38. Kim, M.J., Y.T. Jeong, B.S. Hwang, Y. Hwang, D.W. Jeon and?Y.T. Oh. 2022. Anti-melanogenic activities of Ranunculus?chinensis Bunge via ERK1/2-mediated MITF downregulation.?Korean J. Plant Res. 35(6):704-712 (in Korean).? 

  39. Kim, S.J., G.S. Lee, S.H. Moh, J.B. Park, C.K. Auh, Y.J. Chung,?T.K. Ryu and T.K. Lee. 2013. Phenolic contents and antioxidant activities of six edible seaweeds. J. Korea Acad-Ind.?Coop. Soc. 14(6):3081-3088 (in Korean).? 

  40. Kim, Y.J. and H. Uyama. 2005. Tyrosinase inhibitors from?natural and synthetic sources: structure, inhibition mechanism?and perspective for the future. Cell. Mol. Life. Sci. 62(15):1707-1723.? 

  41. Kim, Y.J. and J.S. Lee. 2020. Microbiological characteristics of?whitening tyrosinase inhibitor-producing wild yeasts, Saccharomyces cerevisiae WJSL0191 and Papiliotrema laurentii?ON30 and production. Korean J. Mycol. 48(3):285-296 (in?Korean).? 

  42. Kolb, N., L. Vallorani, N. Milanovic and V. Stocchi. 2004.?Evaluation of marine algae wakame (Undaria pinnatifida)?and kombu (Laminaria digitata japonica) as food supplements.?Food. Technol. Biotech. 42(1):57-62.? 

  43. Kumari, S., K. Singh, P. Kushwaha and K.S. Kumar. 2022.?Functional and niochemical properties of some economically?important edible seaweeds. Curr. Res. Nutr. Food Sci. 10(2):802-816. 

  44. Lee, C.H., Y.N. Park and S.G. Lee. 2020. Analysis and comparison of bioactive compounds and total 1. antioxidant capabilities of Korean brown algae. Korean J. Food Sci. Technol.?52(1):54-59 (in Korean).? 

  45. Lee, J.D., H.B. Hyun, H.J. Hyeon, E.B. Jang, M.-H. Ko, W.-J.?Yoon, Y. M. Han, Y.-H. Jung, H. Choi, E.G. O and D. Oh. 2021. Mass proliferation of Hibiscus hamabo adventitious?root in an air-lift bioreactor and the antioxidant and whitening?activity of the extract. Korean J. Plant Res. 35(4):435-444 (in?Korean).? 

  46. Liu, X., W. Yuan and X. Meng. 2017. Extraction and quantification of phlorotannins from edible brown algae. J. ASABE.?60(1):265-271.? 

  47. Lozano Mun?oz, I. and N.F. Diaz. 2020. Minerals in edible seaweed: health benefits and food safety issues. Crit. Rev. Food?Sci. 62(6):1592-1607.? 

  48. Machu, L., L. Misurcova, J. Vavra Ambrozova, J. Orsavova, J.?Mlcek, J. Sochor and T. Jurikova. 2015. Phenolic content?and antioxidant capacity in algal food products. Molecules?20(1):1118-1133.? 

  49. Mekinic, G.I., D. Skroza, V. Simat, I. Hamed, M. Cagalj and Z.?Popovic Perkovic. 2019. Phenolic content of brown algae?(Pheophyceae) species: extraction, identification, and quantification. Biomolecules 9(6):244.? 

  50. Moon, H.J., K.S. Park, M.J. Ku, M.S. Lee, S.H. Jeong, T.I. Imbs,?T.N. Zvyagintseva, S.P. Ermakova and Y.H. Lee. 2009.?Effect of Costaria costata fucoidan on expression of matrix?metalloproteinase-1 promoter, mRNA, and protein. J. Nat.?Prod. 72(10):1731-1734.? 

  51. Moreno, M.I.N., M.I. Isla, A.R. Sampietro and M.A. Vattuone. 2000. Comparison of the free radical-scavenging activity of?propolis from several regions of Argentina. J. Ethnopharmacol.?71(1-2):109-114.? 

  52. Na, Y.J., D.V. Jeon, S.J. Han, C.A.O. Maranguy, D.S. An, H.K.?Cha, J.B. Lee, J.H. Yang, H.W. Lee and H.G. Choi. 2016.?Crossed effects of light and temperature on the growth and?maturation of gametophytes in Costaria costata and Undaria?pinnatifida. Korean J. Fish. Aquat Sci. 49(2):190-197 (in?Korean).? 

  53. Naidoo, L., N. Khoza and N.C. Dlova. 2016. A fairer face, a?fairer tomorrow? a review of skin lighteners. Cosmetics?3(3):33.? 

  54. Nakano, Y. and K. Asada. 1981. Hydrogen peroxide is scavenged?by ascorbate-specific peroxidase in spinach chloroplasts.?Plant. Cell. Physiol. 22(5):867-880.? 

  55. Nowak, A., K. Florkowska, J. Zielonka-Brzezicka, W. Duchnik,?A. Muzykiewicz and A. Klimowicz. 2021. The effects of?extraction techniques on the antioxidant potential of extracts?of different parts of milk thistle (Silybum marianum L.). Acta?Sci. Pol. Technol. Aliment. 20(1):37-46.? 

  56. Pak, W.M., K.B.W.R. Kim, M.J. Kim, J.H. Park, N.Y. Bae, S.H.?Park and D.H. Ahn. 2016. Anti-melanogenesis and antiwrinkle effects of Sargassum micracanthum extracts. Microbiol. Biotechnol. Lett. 44(1):19-25 (in Korean).? 

  57. Park, S.K., J.S. Heo, B.Y. Kim, J.N. Song, G.Y. Lim, H.N. Kim?and H.G. Choi. 2011. Comparison on the growth of Costaria?costata and Undaria pinnatifida sporophytes in culture and?their field populations. Korean J. Fish. Aquat Sci. 44(1):71-77 (in Korean)? 

  58. Ribeiro, I.A., J. Rocha, B. Sepodes, H. Mota-Filipe and M.H.?Ribeiro. 2008. Effect of naringin enzymatic hydrolysis towards?naringenin on the anti-inflammatory activity of both compounds.?J. Mol. Catal. B Enzym. 52:13-18.? 

  59. Rushdi, M.I., I.A. Abdel-Rahman, H. Saber, E.Z. Attia and?U.R. Abdelmohsen. 2022. The natural products and pharmacological biodiversity of brown algae from the genus?Dictyopteris. J. Mex. Chem. Soc. 66(1):154-180.? 

  60. Ryzhik, I.V., М.P. Кlindukh and Е.О. Dobychina. 2021. The?B-group vitamins in the red alga Palmaria palmatа (Barents?Sea): Composition, seasonal changes and influence of abiotic?factors. Algal Res. 59:102473.? 

  61. Seo, Y.R., S.H. Kim and H.S. Song. 2018. Change in the quality?of doenjang with Added Saccharina japonica powder fermented by lactic acid bacteria. Korean J. Fish. Aquat Sci. 51(5):477-490 (in Korean).? 

  62. Shin, H.C., H.J. Hwang, K.J. Kang and B.H. Lee. 2006. An?antioxidative and antiinflammatory agent for potential treatment of osteoarthritis from Ecklonia cava. Arch. Pharm Res.?29(2):165-171.? 

  63. Shin, S.C., M.W. Ahn, J.S. Lee, Y.S. Kim and K.P. Park. 2013.?Extraction of fucoxanthin from Undaria pinnatifida and stability of fucoxanthin. Korean Chem. Eng. Res. 51(1):42-46?(in Korean).? 

  64. Tabakaeva, O. and A. Tabakaev. 2016. Amino acids from potentially commercial far-east brown algae Costaria costata and?Undaria pinnatifida. Chem. Nat. Compd. 52(2):376-378.? 

  65. Tanna, B. and A. Mishra. 2019. Nutraceutical potential of seaweed polysaccharides: structure, bioactivity, safety, and?toxicity. Compr. Rev. Food Sci. Food Saf. 18(3):817-831.? 

  66. Yagi, A., T. Kanbara and N. Morinobu. 1987. Inhibition of?Mushroom-Tyrosinase by Aloe Extract. Planta Med. 53(06):?515-517.? 

  67. Yao, Y., H. Xiang, L. You, C. Cui, D. Sun-Waterhouse and M.?Zhao. 2017. Hypolipidaemic and antioxidant capacities of?polysaccharides obtained from Laminaria japonica by different?extraction media in diet-induced mouse model. Int. J. Food?Sci. Tech. 52(10):2274-2281.? 

  68. Youn, J.S., Y.J. Kim, H.J. Na, H.R. Jung, C.K. Song, S.Y. Kang?and J.Y. Kim. 2019. Antioxidant activity and contents of leaf?extracts obtained from Dendropanax morbifera LEV are?dependent on the collecting season and extraction condition.?Food Sci. Biotechnol. 28(1):201-207.? 

  69. Zeng, M., X. Wu, F. Li, W. She, L. Zhou, B. Pi, Z. Xu and X.?Huang. 2017. Laminaria japonica polysaccharides effectively?inhibited the growth of nasopharyngeal carcinoma cells in?vivo and in vitro study. Exp. Toxicol Pathol. 69(7):527-532.? 

저자의 다른 논문 :

관련 콘텐츠

오픈액세스(OA) 유형

GOLD

오픈액세스 학술지에 출판된 논문

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로