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비전염성 질환으로서 치아우식증에 대한 예방 전략
Strategies for the Prevention of Dental Caries as a Non-Communicable Disease 원문보기

大韓小兒齒科學會誌 = Journal of the Korean academy of pediatric dentistry, v.50 no.2, 2023년, pp.131 - 141  

김재곤 (전북대학교 치과대학 소아치과학교실 및 구강생체과학연구소)

초록
AI-Helper 아이콘AI-Helper

치아우식증은 치아, 바이오필름(biofilm), 식이 요인의 상호작용을 기본으로 타액, 불소 등의 구강 환경요인과 생물학적, 행동적, 사회문화적, 유전적 요인이 관여하는 복잡한 다인성질환이다. 최근 치아우식증은 외부 병원체의 감염에 의한 것이 아닌 구강 미생물군의 생태적 변화에 따른 불균형(dysbiosis)의 결과로 이해되면서 전염성질병에서 비전염성 질병(non-communicable diseases, NCD)으로 전환되었다. 치아우식증은 심혈관질환이나 당뇨병과 같이 만성적으로 진행되는 비전염성 질환(NCD) 특성을 가지며, 식이섭취와 생활 습관과 환경적 요소들이 관여한다는 점에서 유사성이 있다. 높은 유병률과 함께 사람들의 건강과 삶의 질에 미치는 영향을 감안할 때 효과적인 구강 건강관리를 목표로 비전염성질환(NCD)로서 치아우식증에 대한 이해가 필요하며, 구강 미생물군의 생태적 균형을 이루기 위한 적절한 예방법과 효율적인 공중보건 정책들이 제공되어야 할 것이다.

Abstract AI-Helper 아이콘AI-Helper

Dental caries is a multifactorial disease influenced by interactions between teeth, biofilm, dietary factors, and various biological, behavioral, sociocultural, and genetic factors. Recent research has shown that dental caries results from dysbiosis, an imbalance in the oral microbial community, shi...

주제어

참고문헌 (71)

  1. Ministry of Health and Welfare. Korean Children's?Oral Health Survey in 2015. Available from URL:?https://www.mohw.go.kr/react/jb/sjb030301vw.jsp?PAR_MENU_ID03&MENU_ID0321&CONT_SEQ332448 (Accessed on March 20, 2020). 

  2. World Health Organization. Noncommunicable Diseases. Available from URL: https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases (Accessed on February 19, 2021). 

  3. Anderson MH : Changing paradigms in caries management. Curr Opin Dent, 2:157-162, 1992. 

  4. Limeback H : Treating dental caries as an infectious?disease. Applying the medical model in practice to?prevent dental caries. Ont Dent, 73:23-25, 1996. 

  5. Ayres JS, Trinidad NJ, Vance RE : Lethal inflame-masome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota. Nat?Med, 18:799-806, 2012. 

  6. Giacaman RA, Araneda E, Padilla C : Association between biofilm-forming isolates of mutans streptococci and caries experience in adults. Arch Oral Biol,?55:550-554, 2010. 

  7. Machiulskiene V, Campus G, Carvalho JC, Dige I, Ekstrand KR, Jablonski-Momeni A, Maltz M, Manton DJ,?Martignon S, Martinez-Mier EA, Pitts NB, Schulte AG,?Splieth CH, Tenuta LMA, Zandona AF, Nyvad B : Terminology of dental caries and dental caries management: consensus report of a workshop organized by?ORCA and Cariology Research Group of IADR. Caries?Res, 54:7-14, 2020. 

  8. Rosier BT, Marsh PD, Mira A : Resilience of the oral?microbiota in health: Mechanisms that prevent dysbiosis. J Dent Res, 97:371-380, 2018. 

  9. Pitts NB, Twetman S, Fisher J, Marsh PD : Understanding dental caries as a non-communicable disease. Br Dent J, 231:749-753, 2021. 

  10. Giacaman RA, Fernandez CE, Munoz-Sandoval C,?Leon S, Garcia-Manriquez N, Echeverria C, Valdes S,?Castro RJ, Gambetta-Tessini K : Understanding dental caries as a non-communicable and behavioral disease: Management implications. Front Oral Health, 3:764479, 2022. 

  11. Balakumar P, Maung-U K, Jagadeesh G. Prevalence?and prevention of cardiovascular disease and diabetes mellitus. Pharmacol Res, 113:600-609, 2016. 

  12. Koch R : Die Aetiologie der Tuberculose. Mitt Kaiser?Gesundh, 2:428-445, 1884. 

  13. Fredricks DN, Relman DA : Sequence-based identification of microbial pathogens: a reconsideration of?Koch's postulates. Clin Microbiol Rev, 9:18-33, 1996. 

  14. Loesche WJ : Role of Streptococcus mutans in human?dental decay. Microbiol Rev, 50:353-380, 1986. 

  15. Ayres JS, Trinidad NJ, Vance RE : Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota. Nat?Med, 18:799-806, 2012. 

  16. World Health Organization. Global status report on noncommunicable diseases 2014. Available from URL: http://apps.who.int/iris/bitstream/10665/148114/1/9789241564854_eng.pdf (Accessed?on January 21, 2015). 

  17. FDI World Dental Federation. WHA72 - Follow-Up?to the High-Level Meeting on NCDs. Available from?URL: https://www.fdiworlddental.org/wha72-followhigh-level-meeting-ncds (Accessed on February 19,?2021). 

  18. World Health Organization. Global health risks: mortality and burden of disease attributable to selected?major risks. Available from URL: https://apps.who.int/iris/bitstream/handle/10665/44203/9789241563871_eng.pdf?sequence1&isAllowedy (Accessed on February 27, 2014). 

  19. World Health Organization. Noncommunicable Diseases. Available from URL: https://www.who.int/health-topics/noncommunicable-diseases#tabtab_1?(Accessed on April 2, 2021). 

  20. Lee HJ, Choi EK, Park JB, Han KD, Oh S : Tooth loss?predicts myocardial infarction, heart failure, stroke,?and death. J Dent Res, 98:164-170, 2019. 

  21. Daly B, Thompsell A, Sharpling J, Rooney YM, Hillman L, Wanyonyi KL, White S, Gallagher JE : Evidence summary: the relationship between oral health?and dementia. Br Dent J, 223:846-853, 2018. 

  22. Wilson M : Microbial inhabitants of humans. Their?ecology and role in health and disease. Cambridge?University Press, London, 2005. 

  23. Devine DA, Marsh PD, Meade J : Modulation of host?responses by oral commensal bacteria. J Oral Microbiol, 7:26941, 2015. 

  24. Chen T, Yu WH, Izard J, Baranova OV, Lakshmanan?A, Dewhirst FE : The Human Oral Microbiome Database: a web accessible resource for investigating oral?microbe taxonomic and genomic information. Database (Oxford), 2010:baq013, 2010. 

  25. Sutherland IW : The biofilm matrix - an immobilized?but dynamic microbial environment. Trends Microbiol, 9:222-227, 2001. 

  26. Hoiby N, Bjarnsholt T, Givskov M, Molin S, Ciofu O : Antibiotic resistance of bacterial biofilms. Int J Antimicrob Agents, 35:322-332, 2010. 

  27. Klein MI, Hwang G, Santos PH, Campanella OH, Koo?H : Streptococcus mutans-derived extracellular matrix in cariogenic oral biofilms. Front Cell Infect Microbiol, 5:10, 2015. 

  28. Kim M, Jeon J, Kim J : Streptococcus mutans extracellular DNA levels depend on the number of bacteria in?a biofilm. Sci Rep, 8:13313, 2018. 

  29. Sikdar R, Elias M : Quorum quenching enzymes and?their effects on virulence, biofilm, and microbiomes:?a review of recent advances. Expert Rev Anti Infect?Ther, 18:1221-1233, 2020. 

  30. da Silva RAG, Afonina I, Kline KA : Eradicating biofilm infections: an update on current and prospective?approaches. Curr Opin Microbiol, 63:117-125, 2021. 

  31. Marsh PD : Microbial ecology of dental plaque and?its significance in health and disease. Adv Dent Res,?8:263-271, 1994. 

  32. Marsh PD : Microbiology of Dental Plaque Biofilms?and Their Role in Oral Health and Caries. Dent Clin?North Am, 54:441-454, 2010. 

  33. Li YH, Huang X, Tian XL : Recent advances in dental?biofilm: impacts of microbial interactions on the biofilm ecology and pathogenesis. AIMS Bioengineering,?4:335-350, 2017. 

  34. Kilian M, Chapple ILC, Hannig M, Marsh PD, Meuric?V, Pedersen AML, Tonetti MS, Wade WG, Zaura E :?The oral microbiome - an update for oral healthcare?professionals. Br Dent J, 221:657-666, 2016. 

  35. Bradshaw DJ, McKee AS, Marsh PD : Effects of carbohydrate pulses and pH on population shifts within?oral microbial communities in vitro. J Dent Res, 68:?1298-1302, 1989. 

  36. Takahashi N, Nyvad B : Caries ecology revisited: microbial dynamics and the caries process. Caries Res,?42:409-418, 2008. 

  37. Takahashi N, Nyvad B : The role of bacteria in the caries process: ecological perspectives. J Dent Res, 90:294-303, 2011. 

  38. Hajishengallis G, Darveau RP, Curtis MA : The keystone-pathogen hypothesis. Nat Rev Microbiol, 10:717-725, 2012. 

  39. Hajishengallis E, Parsaei Y, Klein MI, Koo H : Advances in the microbial etiology and pathogenesis of early?childhood caries. Mol Oral Microbiol, 32:24-34, 2017. 

  40. Twetman S : Prevention of dental caries as a non-communicable disease. Eur J Oral Sci, 126 Suppl 1:19-25, 2018. 

  41. Head D, A Devine D, Marsh PD : In silico modelling to?differentiate the contribution of sugar frequency versus total amount in driving biofilm dysbiosis in dental caries. Sci Rep, 7:17413, 2017. 

  42. Guideline: Sugars intake for adults and children.?World Health Organization, Geneva, 2015. 

  43. Giacaman RA : Sugars and beyond. The role of sugars?and the other nutrients and their potential impact on?caries. Oral Dis, 24:1185-1197, 2018. 

  44. Janket SJ, Benwait J, Isaac P, Ackerson LK, Meurman?JH : Oral and Systemic Effects of Xylitol Consumption. Caries Res, 53:491-501, 2019. 

  45. Marttinen AM, Ruas-Madiedo P, Hidalgo-Cantabrana?C, Saari MA, Ihalin RA, Soderling EM : Effects of xylitol on xylitol-sensitive versus xylitol-resistant Streptococcus mutans strains in a three-species in vitro biofilm. Curr Microbiol, 65:237-243, 2012. 

  46. von Philipsborn PV, Stratil JM, Burns J, Busert LK,?Pfadenhauer LM, Polus S, Holzapfel C, Hauner H,?Rehfuess E : Environmental interventions to reduce?the consumption of sugar-sweetened beverages and?their effects on health. Cochrane Database Syst Rev,?18:205-218, 2019. 

  47. Mira A, Simon-soro A, Curtis MA : Role of microbial communities in the pathogenesis of periodontal?diseases and caries. J Clin Periodontol, 44 Suppl 18:S23-S38, 2017. 

  48. Stone VN, Xu P : Targeted antimicrobial therapy in?the microbiome era. Mol Oral Microbiol, 32:446-454, 2017. 

  49. Bruun C, Givskov H, Thylstrup A : Whole saliva fluoride after toothbrushing with NaF and MFP dentifrices with different F concentrations. Caries Res, 18:282-288, 1984. 

  50. Walsh T, Oliveira-Neto JM, Moore D : Chlorhexidine treatment for the prevention of dental caries in children and adolescents. Cochrane Database Syst Rev, 4:CD008457, 2015 

  51. Rethman MP, Beltran-Aguilar ED, Billings RJ, Hujoel PP, Katz BP, Milgrom P, Sohn W, Stamm JW, Watson G, Wolff M, Wright JT, Zero D, Aravamudhan K,?Frantsve-Hawley J, Meyer DM; American Dental Association Council on Scientific Affairs Expert Panel?on Nonfluoride Caries-Preventive Agents : Nonfluoride caries-preventive agents: executive summary of?evidence-based clinical recommendations. J Am Dent?Assoc, 142:1065-1671, 2011. 

  52. Freires IA, Denny C, Benso B, de Alencar SM, Rosalen?PL : Antibacterial Activity of Essential Oils and Their?Isolated Constituents against Cariogenic Bacteria: A?Systematic Review. Molecules, 20:7329-7358, 2015. 

  53. Lee SY, Kim JG, Baik BJ, Yang YM, Lee KY, Lee YH,?Kim MA : Antibacterial Effect of Essential Oils on Oral?Bacteria. J Korean Acad Pediatr Dent, 36:2-11, 2009. 

  54. Koczulla AR, Bals R : Antimicrobial peptides: current?status and therapeutic potential. Drugs, 63:389-406, 2003. 

  55. Maltz M, Beighton D : Multidisciplinary research?agenda for novel antimicrobial agents for caries prevention and treatment. Adv Dent Res, 24:133-136, 2012. 

  56. Senadheera D, Cvitkovitch DG : Quorum sensing and?biofilm formation by Streptococcus mutans; in Utsumi R (ed). Bacterial Signal Transduction: Networks?and Drug Targets. Springer, New York, 178-188, 2008. 

  57. Janus MM, Crielaard W, Zaura E, Keijser BJ, Brandt?BW, Krom BP : A novel compound to maintain a?healthy oral plaque ecology in vitro. J Oral Microbiol,?8:32513, 2016. 

  58. Ten Cate JM, Featherstone JD : Mechanistic aspects of?the interactions between fluoride and dental enamel.?Crit Rev Oral Biol Med, 2:283-296, 1991. 

  59. Fejerskov O, Thylstrup A, Larsen MJ : Rational use?of fluorides in caries prevention. A concept based?on possible cariostatic mechanisms. Acta Odontol?Scand, 39:241-249, 1981. 

  60. Whitford GM, Schuster GS, Pashley DH, Venkateswarlu P : Fluoride uptake by Streptococcus mutans 6715.?Infect Immun, 18:680-687, 1977. 

  61. Fontana M, Cabezas CG, Fitzgerald M : Cariology for?the 21st century: current caries management concepts for dental practice. J Mich Dent Assoc, 95:32-40, 2013. 

  62. Crystal YO, Niederman R : Evidence-Based Dentistry?Update on Silver Diamine Fluoride. Dent Clin North?Am, 63:45-68, 2019. 

  63. Horst JA, Heima M : Prevention of Dental Caries by?Silver Diamine Fluoride. Compend Contin Educ Dent,?40:158-163, 2019. 

  64. Toumba KJ, Twetman S, Splieth C, Parnell C, van Loveren C, Lygidakis NΑ : Guidelines on the use of fluoride for caries prevention in children: an updated?EAPD policy document. Eur Arch Paediatr Dent, 20:507-516, 2019. 

  65. Leone CW, Oppenheim FG : Physical and chemical?aspects of saliva as indicators of risk for dental caries?in humans. J Dent Educ, 65:1054-1062, 2001. 

  66. Furness S, Worthingthon HV, Bryan G, Birchenough?S, Mcmillan R : Interventions for the management of?dry mouth: topical therapies. Cochrane Database Syst?Rev, 12:CD008934, 2011. 

  67. Zaura E, Twetman S : Critical Appraisal of Oral Pre-and Probiotics for Caries Prevention and Care. Caries?Res, 53:514-526, 2019. 

  68. Huang X, Zhang K, Deng M, Exterkate RAM, Liu C,?Zhou X, Cheng L, Ten cate JM : Effect of arginine on?the growth and biofilm formation of oral bacteria.?Arch Oral Biol, 82:256-262, 2017. 

  69. Zheng X, Cheng X, Wang L, Qiu W, Wang S, Zhou Y,?Li M, Li Y, Cheng L, Li J, Zhou X, Xu X : Combinatorial effects of arginine and fluoride on oral bacteria. J?Dent Res, 94:344-353, 2015. 

  70. Gruner D, Paris S, Schwendicke F : Probiotics for?managing caries and periodontitis: systematic review?and meta-analysis. J Dent, 48:16-25, 2016. 

  71. Lin TH, Lin CH, Pan TM : The implication of probiotics in the prevention of dental caries. Appl Microbiol?Biotechnol, 102:577-586, 2018. 

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