최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Journal of hepatology : the journal of the European Association for the Study of the Liver, v.32 no.2, 2000년, pp.279 - 286
Drozdzik, Marek (Division of Hepatology and Gene Therapy, Department of Medicine, School of Medicine and Clinica Universitaria, University of Navarra, Pamplona, Spain) , Qian, Cheng (Cheng Qian or Prof. Jesus Prieto, Division of Hepatology and Gene Therapy, Department of Medicine, School of Medicine and Clinica Universitaria, University of Navarra, Irunlarrea s) , Xie, Xiaoming (Division of Hepatology and Gene Therapy, Department of Medicine, School of Medicine and Clinica Universitaria, University of Navarra, Pamplona, Spain) , Peng, Dacheng (Division of Hepatology and Gene Therapy, Department of Medicine, School of Medicine and Clinica Universitaria, University of Navarra, Pamplona, Spain) , Bilbao, Roberto (Division of Hepatology and Gene Therapy, Department of Medicine, School of Medicine and Clinica Universitaria, University of Navarra, Pamplona, Spain) , Mazzolini, Guillermo (Division of Hepatology and Gene Therapy, Department of Medicine, School of Medicine and Clinica Universitaria, University of Navarra, P) , Prieto, Jesus
AbstractBackground/Aims: Gene therapy has emerged as a new form of treatment for unresectable hepatocellular carcinoma (HCC). We evaluate here the effect of IL-12 and the suicide gene thymidine kinase as single agents and in combination to treat experimental liver cancer.Methods: Recombinant adenovi...
J Hepatol Colombo 15 225 1995 10.1016/0168-8278(92)90041-M Hepatocellular carcinoma
J Clin Oncol Venook 12 1323 1994 10.1200/JCO.1994.12.6.1323 Treatment of hepatocellular carcinoma: too many options?
Immunol Today Chouaib 18 493 1997 10.1016/S0167-5699(97)01115-8 The host-tumor immune conflict: from immunosuppression to resistance and destruction
Adv Immunol Roth 57 281 1994 10.1016/S0065-2776(08)60675-6 Immune response against tumors
Nat Med Gabrilovich 2 1096 1996 10.1038/nm1096-1096 Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
Immunol Today Zier 17 39 1996 10.1016/0167-5699(96)80567-6 Preventing abnormalities in signal transduction of T cells in cancer: the promise of cytokine gene therapy
Immunol Today Musiani 18 32 1997 10.1016/S0167-5699(97)80012-6 Cytokine, tumor-cell death and immunogenicity: a question of choice
Immunol Today Schmidt-Wolf 16 173 1995 10.1016/0167-5699(95)80116-2 Cytokines and gene therapy
Immunol Today Colombo 15 48 1994 10.1016/0167-5699(94)90131-7 Cytokine gene transfer in tumor inhibition and tumor therapy: where are we now?
Immunol Today Lamonta 17 214 1996 10.1016/0167-5699(96)30011-X IL-12: a key cytokine in immune regulation
J Immunol Wolf 146 3074 1991 10.4049/jimmunol.146.9.3074 Cloning of cDNA for natural killer cell stimulatory factor, a heterdimeric cytokine with multiple biologic effect on T and natural killer cells
Proc Natl Acad Sci USA Seder 90 10188 1993 10.1073/pnas.90.21.10188 IL-12 acts directly on CD4+ T cells to enhance priming for IFN-γ production and diminishes IL-4 inhibition of such priming
Int Immunol Gately 6 157 1994 10.1093/intimm/6.1.157 Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocytes activity and induces production of IFN-γ in vivo
J Natl Cancer Inst Voest 87 581 1995 10.1093/jnci/87.8.581 Interleukin-12 inhibits angiogenesis in vivo
J Exp Med Brunda 178 1223 1993 10.1084/jem.178.4.1223 Antitumor and antimetastatic activity of interleukin-12 against murine tumors
J Immunol Nastala 153 1697 1994 10.4049/jimmunol.153.4.1697 Recombinant interleukin-12 administration induces tumor regression in association with interferon-γ production
Cancer Res Mu 55 4404 1995 Administration of recombinant interleukin-12 prevents outgrowth of tumor cells metastasizing spontaneously to lung and lymph nodes
J Immunol Tannenbaum 156 693 1996 10.4049/jimmunol.156.2.693 Cytokine and chemokine expression in tumors of mice receiving systemic therapy IL-12
Proc Natl Acad Sci USA Noguchi 93 11798 1996 10.1073/pnas.93.21.11798 Effect of interleukin 12 on tumor induction by 3-methylcolantrene
Science Marshall 268 1555 1995 10.1126/science.268.5217.1555 Cancer trial of interleukin-12 halted
J Natl Cancer Inst Jenks 88 576 1996 10.1093/jnci/88.9.576 After initial setback, IL-12 regaining popularity
Hum Gene Ther Bramson 7 1995 1996 10.1089/hum.1996.7.16-1995 Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12
Proc Natl Acad Sci Caruso 93 11302 1996 10.1073/pnas.93.21.11302 Adenovirus mediated interleukin-12 gene therapy for metastatic colon carcinoma
J Immunol Toda 160 4457 1998 10.4049/jimmunol.160.9.4457 In situ cancer vaccination: an IL-12 defective vector/replication-competent herpes simplex virus combination induces local and systemic antitumor activity
Proc Natl Acad Sci Rakhmilevich 93 6291 1996 10.1073/pnas.93.13.6291 Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors
J Immunol Tahara 154 6466 1995 10.4049/jimmunol.154.12.6466 Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector
Cancer Res Meko 55 4765 1995 High cytokine production and effective antitumor activity of a recombinant vaccinia virus encoding murine interleukin 12
Cancer Res Tan 56 3399 1996 Injection of complementary DNA encoding interleukin-12 inhibits tumor establishment at distant site in a murine renal carcinoma model
Cancer Gene Ther Moolten 1 279 1994 Drug sensitivity (“suicide”) genes for selective cancer chemotherapy
Qian 537 1997 Viral Hepatitis and Liver Disease In vivo gene therapy of experimental hepatocellular carcinoma using a recombinant defective adenovirus expressing the thymidine-kinase of herpes simplex virus
Hum Gene Ther Qian 8 349 1997 10.1089/hum.1997.8.3-349 Gene transfer and therapy with adenoviral vector in rats with diethylnitrosamine-induced hepatocellular carcinoma
Cancer Gene Ther Will 2 191 1995 Gene therapy for hepatocellular carcinoma: chemosensitivity conferred by adenovirus-mediated transfer of the HSV-1 thymidine kinase gene
Cancer Res Vile 54 6228 1994 Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component
Proc Natl Acad Sci Chen 92 2577 1995 10.1073/pnas.92.7.2577 Combination gene therapy for liver metastasis of colon carcinoma
Cancer Res Chen 56 3758 1996 Combination suicide and cytokine gene therapy for hepatic metastases of colon carcinoma: sustained antitumor immunity prolongs animal survival
Hepatology Qian 22 118 1995 Induction of sensitivity to ganciclovir in human hepatocellular carcinoma cells by adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase
Cancer Gene Ther Mazzolini 6 1999 10.1038/sj.cgt.7700072 Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing IL-12
J Immunol Lasarte 162 5270 1999 10.4049/jimmunol.162.9.5270 Different doses of adenoviral vector expressing IL-12 enhance or depress the immune response to a coadministrated antigen: the role of nitric oxide
Proc Natl Acad Sci Noguchi 92 2219 1995 10.1073/pnas.92.6.2219 Influence of IL-12 on p53 peptide vaccination against established Meth-A sarcoma
Ann NY Acad Sci Nishimura 795 375 1996 10.1111/j.1749-6632.1996.tb52697.x The application of IL-12 to cytokine therapy for tumors
Cancer Res Vagliani 56 467 1996 Interleukin-12 potentates the curative effect of a vaccine based on interleukin-2 transduced tumor cells
Proc Natl Acad Sci Noguchi 93 11798 1996 10.1073/pnas.93.21.11798 Effect of interleukin-12 on tumor induction by 3-methylcholanthrene
Jpn J Med Sci Biol Obana 48 221 1995 10.7883/yoken1952.48.221 Induction of antitumor immunity by mouse tumor cells transfected with mouse interleukin-12 gene
Hum Gene Ther Kianmanesh 8 1807 1997 10.1089/hum.1997.8.15-1807 A“distant” bystander effect of suicide gene therapy: regression of nontransduced tumors together with a distant transduced tumor
Hum Gene Ther Arbuthnot 7 1503 1996 10.1089/hum.1996.7.13-1503 In vitro and in vivo hepatoma cell-specific expression of a gene transferred with an adenoviral vector
Semin Cancer Biol Buendia 3 309 1992 Mammalian hepatitis B viruses and primary liver cancer
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.