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[해외논문] Combined gene therapy with suicide gene and interleukin-12 is more efficient than therapy with one gene alone in a murine model of hepatocellular carcinoma

Journal of hepatology : the journal of the European Association for the Study of the Liver, v.32 no.2, 2000년, pp.279 - 286  

Drozdzik, Marek (Division of Hepatology and Gene Therapy, Department of Medicine, School of Medicine and Clinica Universitaria, University of Navarra, Pamplona, Spain) ,  Qian, Cheng (Cheng Qian or Prof. Jesus Prieto, Division of Hepatology and Gene Therapy, Department of Medicine, School of Medicine and Clinica Universitaria, University of Navarra, Irunlarrea s) ,  Xie, Xiaoming (Division of Hepatology and Gene Therapy, Department of Medicine, School of Medicine and Clinica Universitaria, University of Navarra, Pamplona, Spain) ,  Peng, Dacheng (Division of Hepatology and Gene Therapy, Department of Medicine, School of Medicine and Clinica Universitaria, University of Navarra, Pamplona, Spain) ,  Bilbao, Roberto (Division of Hepatology and Gene Therapy, Department of Medicine, School of Medicine and Clinica Universitaria, University of Navarra, Pamplona, Spain) ,  Mazzolini, Guillermo (Division of Hepatology and Gene Therapy, Department of Medicine, School of Medicine and Clinica Universitaria, University of Navarra, P) ,  Prieto, Jesus

Abstract AI-Helper 아이콘AI-Helper

AbstractBackground/Aims: Gene therapy has emerged as a new form of treatment for unresectable hepatocellular carcinoma (HCC). We evaluate here the effect of IL-12 and the suicide gene thymidine kinase as single agents and in combination to treat experimental liver cancer.Methods: Recombinant adenovi...

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