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European journal of pharmaceutical sciences, v.12 no.3, 2001년, pp.223 - 229
Genty, Muriel (Laboratoires UPSA) , González, Gustavo (fense, France) , Clere, Christian (Department of Analytical Chemistry, University of Seville, Seville E-41012, Spain) , Desangle-Gouty, Valérie (Laboratoires UPSA) , Legendre, Jean-Yves (fense, France)
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AbstractImmobilized artificial membrane (IAM) chromatography coupled to physicochemical descriptors was evaluated to model the passive intestinal absorption of drugs through rat gut sacs. The chromatographic capacity factors (logk′IAM) of 12 structurally diverse compounds were determined on a...
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