$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

[해외논문] NMDA receptor activation in the aged rat hippocampus

Experimental gerontology, v.35 no.9/10, 2000년, pp.1185 - 1199  

Potier, B (Dynamique des Systè) ,  Poindessous-Jazat, F (mes Neuroendocriniens, INSERM U159, 2ter rue d'Alesia, 75014 Paris, France) ,  Dutar, P (Dynamique des Systè) ,  Billard, J.M (mes Neuroendocriniens, INSERM U159, 2ter rue d'Alesia, 75014 Paris, France)

Abstract AI-Helper 아이콘AI-Helper

AbstractAge-related alterations of N-methyl-D-aspartate receptor (NMDAr) activation were investigated in the CA1 field of hippocampal slices from young (3–6 months old) and aged (25–33 months old) Sprague–Dawley rats by using ex vivo extracellular electrophysiological recording ...

주제어

참고문헌 (47)

  1. TINS Artola 16 480 1993 Long-term depression of excitatory synaptic transmission and its relationship to long-term potentiation 

  2. 10.1037/0735-7044.99.6.1040 Barnes, C.A., McNaughton, B., 1985. An age comparison of the rates of acquisition and forgetting of spatial information in relation to long term enhancement of hippocampal synapses. Behav. Neurosci. 99, 1040-1043. 

  3. Hippocampus Barnes 2 457 1992 10.1002/hipo.450020413 Region-specific age effects on AMPA sensitivity: electrophysiological evidence for loss of synaptic contacts in hippocampal field CA1 

  4. Learn. Memory Barnes 3 124 1996 10.1101/lm.3.2-3.124 Functional integrity of NMDA-dependent LTP induction mechanisms across lifespan of F-344 rats 

  5. Neurobiol. Aging Barnes 18 445 1997 10.1016/S0197-4580(97)00044-4 Age-related decrease in the N-Methyl-d-AspartateR-mediated excitatory postsynaptic potential in hippocampal region CA1 

  6. J. Neurophysiol. Billard 74 539 1995 10.1152/jn.1995.74.2.539 Decreased monosynaptic GABAB-mediated inhibitory postsynaptic potentials in hippocampal CA1 pyramidal cells in the aged rat: pharmacological characterization and possible mechanisms 

  7. Neurobiol. Aging Billard 18 535 1997 10.1016/S0197-4580(97)00104-8 NMDA receptor activation in the aged rat: electrophysiological investigations in the CA1 area of the hippocampal slice ex vivo 

  8. TINS Bliss 361 31 1993 A synaptic model of memory: long-term potentiation in the hippocampus 

  9. TINS Collingridge 10 288 1987 NMDA receptors-their role in long term potentiation 

  10. Neurobiol. Aging Deupree 14 249 1993 10.1016/0197-4580(93)90009-Z Age-related alterations in potentiation in the CA1 region in F344 rats 

  11. Eur. J. Neurosci. Dutar 3 839 1991 10.1111/j.1460-9568.1991.tb00095.x Loss of calbindin-28k immunoreactivity in hippocampal slices from aged rats: a role for calcium 

  12. Soc. Neurosci. Abstr. Eckles 23 1456 1997 Functional changes in the NMDA receptor of aged F344 rats 

  13. Soc. Neurosci. Abstr. Eckles 23 2071 1999 Caloric restriction prevents age-related deficits in LTP and NMDA receptor expression 

  14. Brain Res. Rev. Foster 30 236 1999 10.1016/S0165-0173(99)00017-X Involvement of hippocampal synaptic plasticity in age-related memory decline 

  15. Hippocampus Foster 7 602 1997 10.1002/(SICI)1098-1063(1997)7:6<602::AID-HIPO3>3.0.CO;2-G Age-associated changes in Ca2+-dependent processes: relation to hippocampal synaptic plasticity 

  16. Neuroscience Jasek 82 1179 1998 10.1016/S0306-4522(97)00337-0 Pharmacological characterization of ionotropic excitatory amino acid receptors in young and aged rat basal forebrain 

  17. Hippocampus Jeffery 7 95 1997 10.1002/(SICI)1098-1063(1997)7:1<95::AID-HIPO10>3.0.CO;2-D LTP and spatial learning-Where to next? 

  18. Synapse Jouvenceau 26 292 1997 10.1002/(SICI)1098-2396(199707)26:3<292::AID-SYN10>3.0.CO;2-Y Potentiation of glutamatergic EPSPs in rat CA1 hippocampal neurons after selective cholinergic denervation by 192 IgG-saporin 

  19. Hippocampus Jouvenceau 8 627 1998 10.1002/(SICI)1098-1063(1998)8:6<627::AID-HIPO5>3.0.CO;2-X Alteration of NMDA receptor-mediated synaptic responses in CA1 area of the aged rat hippocampus: contribution of GABAergic and cholinergic deficits 

  20. Synapse Jouvenceau 33 172 1999 10.1002/(SICI)1098-2396(19990901)33:3<172::AID-SYN2>3.0.CO;2-S Glutamatergic synaptic responses and long-term potentiation are impaired in the CA1 hippocampal area of calbindin d28k-deficient mice 

  21. Nature Kauer 334 250 1988 10.1038/334250a0 NMDA application potentiates synaptic transmission in the hippocampus 

  22. Kausler 1994 Learning and Memory in Normal Aging 

  23. Kostyuk 1995 Calcium Signaling in the Nervous System 

  24. Ann. N.Y. Acad. Sci. Landfield 747 351 1994 10.1111/j.1749-6632.1994.tb44422.x Increased hippocampal CA2+ channel activity in brain aging and dementia 

  25. Brain Res. Landfield 150 85 1978 10.1016/0006-8993(78)90655-8 Impaired synaptic potentiation processes in the hippocampus of aged, memory deficient rats 

  26. J. Neurosci. Legendre 13 674 1993 10.1523/JNEUROSCI.13-02-00674.1993 Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium 

  27. J. Neurosci. Magnusson 20 1666 2000 10.1523/JNEUROSCI.20-05-01666.2000 Declines in mRNA expression of different subunits may account for differential effect of aging on agonist and antagonist binding to the NMDA receptor 

  28. TINS Malenka 16 521 1993 NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms 

  29. Neuron Malenka 9 121 1992 10.1016/0896-6273(92)90227-5 Temporal limits on the rise in postsynaptic calcium required for the induction of long-term potentiation 

  30. Nature Mayer 309 261 1984 10.1038/309261a0 Voltage-dependence block by Mg2+ of NMDA responses in spinal cord neurons 

  31. J. Physiol. (London) Medina 495 411 1996 10.1113/jphysiol.1996.sp021603 Calcium-induced inactivation of NMDA receptor-channels evolves independently of run-down in cultured rat brain neurons 

  32. Nature Morris 319 774 1986 10.1038/319774a0 Selective impairment of learning and blockade of long-term potentiation by N-Methyl-d-Aspartate receptor antagonist, AP5 

  33. Neurobiol. Aging Nicolle 20 343 1999 No loss of synaptic proteins in the hippocampus of aged, behaviorally impaired rats 

  34. J. Neurosci. Norris 18 3171 1998 10.1523/JNEUROSCI.18-09-03171.1998 Reversal of age-related alterations in synaptic plasticity by blockade of L-type Ca2+ channels 

  35. Nature Nowak 307 462 1984 10.1038/307462a0 Magnesium gates glutamate-activated channels in mouse central neurons 

  36. Eur. J. Neurosci. Papatheodoropoulos 8 510 1996 10.1111/j.1460-9568.1996.tb01235.x Age-related changes in excitability and recurrent inhibition in the rat CA1 hippocampal region 

  37. PNAS Rapp 93 9926 1996 10.1073/pnas.93.18.9926 Preserved neuron number in the hippocampus of aged rats with spatial learning deficits 

  38. Neurobiol. Aging Rasmussen 17 143 1996 10.1016/0197-4580(95)02032-2 Memory impaired aged rats: no loss of principle hippocampal and subicular neurons 

  39. J. Neurophysiol. Rosenmund 73 427 1995 10.1152/jn.1995.73.1.427 Calcium-dependent inactivation of synaptic NMDA receptors in hippocampal neurons 

  40. J. Neurophysiol. Shankar 79 334 1998 10.1152/jn.1998.79.1.334 Aging differentially alters form of long-term potentiation i rat hippocampal area CA1 

  41. Neurobiol. Aging Shimada 18 329 1997 10.1016/S0197-4580(97)80315-6 N-Methyl-d-Aspartate receptor binding in brains of rat at different ages 

  42. Neuron Stevens 20 1 1998 10.1016/S0896-6273(00)80426-2 A million dollar question: does LTP=memory? 

  43. Science Thibault 272 1017 1996 10.1126/science.272.5264.1017 Increase in single L-type calcium channels in hippocampal neurons during aging 

  44. Cell Calcium Thibault 24 417 1998 10.1016/S0143-4160(98)90064-1 Calcium dysregulation in neuronal aging and Alzheimer's disease: history and new directions 

  45. Cell Tsien 87 1327 1996 10.1016/S0092-8674(00)81827-9 The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory 

  46. TINS Verkhratsky 21 2 1998 Calcium and neuronal ageing 

  47. Eur. J. Neurosci. Villa 6 1491 1994 10.1111/j.1460-9568.1994.tb01010.x Cytosolic Ca2+ binding proteins during rat brain aging: loss of calbindin and calretinin in the hippocampus, with no change in the cerebellum 

관련 콘텐츠

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로