[논문]A Randomized, Placebo-Controlled Trial Evaluating Changes in Peripheral Neuropathy and Quality of Life by Using Low-Frequency Electrostimulation on Breast Cancer Patients Treated With Chemotherapy

Song, Si-Yeon; Park, Ji-Hye; Lee, Jin Sun; Kim, Je Ryong; Sohn, Eun Hee; Jung, Mi Sook; Yoo, Hwa-Seung

doi:10.1177/1534735420925519

[해외논문] A Randomized, Placebo-Controlled Trial Evaluating Changes in Peripheral Neuropathy and Quality of Life by Using Low-Frequency Electrostimulation on Breast Cancer Patients Treated With Chemotherapy 원문보기

Integrative cancer therapies, v.19, 2020년, pp.1534735420925519 -

Song, Si-Yeon (Dunsan Korean Medicine Hospital of Daejeon University, Daejeon, Republic of Korea) , Park, Ji-Hye (Seoul Korean Medicine Hospital of Daejeon University, Seoul, Republic of Korea) , Lee, Jin Sun (Chungnam National University, Daejeon, Republic of Korea) , Kim, Je Ryong (Chungnam National University, Daejeon, Republic of Korea) , Sohn, Eun Hee (Chungnam National University Hospital, Daejeon, Republic of Korea) , Jung, Mi Sook (Chungnam National University, Daejeon, Republic of Korea) , Yoo, Hwa-Seung (Seoul Korean Medicine Hospital of Daejeon University, Seoul, Republic of Korea)

Abstract ▼ AI-Helper

Background: This study examined the effect of a portable low-frequency electrostimulation (ES) device on patients diagnosed with chemotherapy-induced peripheral neuropathy (CIPN) immediately after chemotherapy for breast cancer. Methods: A single-center, randomized, placebo-controlled trial was conducted. A total of 72 patients newly diagnosed with CIPN were enrolled and randomly placed into the ES (n = 36) or the sham ES group (SES; n = 36). Duloxetine or pregabalin was prescribed to all participants from the initial assessment. The devices for 14 days, at least twice a day, for at least 120 minutes. The primary outcomes were the overall intensities of the CIPN symptoms as assessed using Numerical Rating Scale (NRS). Secondary outcomes included Total Neuropathy Score (TNS), European Organization for Research and Treatment of Cancer Quality of Life (EORTC-QLQ), Chemotherapy-Induced Peripheral Neuropathy 20 (CIPN20), Functional Assessment of Cancer Therapy-Breast (FACT-B), and Instrument on Pattern Identification and Evaluation for CIPN (IPIE-CIPN). Results: No differences in NRS scores were found between the patients in the ES and the SES group (P = 0.267). Patients in both groups showed significantly reduced CIPN intensities (ES P < .001; SES P < .001). No significant differences between the groups were found in TNS, EORTC-QLQ, CIPN20, and FACT-B. The general symptoms of CIPN diagnosed as cold arthralgia showed significance only in the ES group (P = .006). Conclusion: Compared with a placebo, the effectiveness of the low-frequency ES device with pharmacological intervention was not significantly different, but a therapeutic effect was possible.

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참고문헌 (41)

1 Siegel RL Miller KD Jemal A. Cancer statistics, 2018 . CA Cancer J Clin . 2018 ; 68 : 7 - 30 . 29313949
2 Ministry of Health and Welfare KCCR; National Cancer Center . Annual report of cancer statistics in Korea in 2016 . https://ncc.re.kr/main.ncc?uri=english/sub04_Statistics . Accessed April 28, 2020 .
3 Howard-Anderson J Ganz PA Bower JE Stanton AL. Quality of life, fertility concerns, and behavioral health outcomes in younger breast cancer survivors: a systematic review . J Natl Cancer Inst . 2012 ; 104 : 386 - 405 . 22271773

상세보기
4 Greenlee H DuPont-Reyes MJ Balneaves LG , et al Clinical practice guidelines on the evidence-based use of integrative therapies during and after breast cancer treatment . CA Cancer J Clin . 2017 ; 67 : 194 - 232 . 28436999
5 Zajczkowska R Kocot-Kpska M Leppert W Wrzosek A Mika J Wordliczek J. Mechanisms of chemotherapy-induced peripheral neuropathy . Int J Mol Sci . 2019 ; 20 : 1451 .
6 Starobova H Vetter I. Pathophysiology of chemotherapy-induced peripheral neuropathy . Front Mol Neurosci . 2017 ; 10 : 174 . 28620280

상세보기
7 Greenlee H Crew KD Capodice J , et al Randomized sham-controlled pilot trial of weekly electro-acupuncture for the prevention of taxane-induced peripheral neuropathy in women with early stage breast cancer . Breast Cancer Res Treat . 2016 ; 156 : 453 - 464 . 27013473

상세보기
8 Seidman AD Hudis CA Albanell J , et al Dose-dense therapy with weekly 1-hour paclitaxel infusions in the treatment of metastatic breast cancer . J Clin Oncol . 1998 ; 16 : 3353 - 3361 . 9779712

상세보기
9 Smith RE Brown AM Mamounas EP , et al Randomized trial of 3-hour versus 24-hour infusion of high-dose paclitaxel in patients with metastatic or locally advanced breast cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-26 . J Clin Oncol . 1999 ; 17 : 3403 - 3411 . 10550134
10 Lee JJ Swain SM. Peripheral neuropathy induced by microtubule-stabilizing agents . J Clin Oncol . 2006 ; 24 : 1633 - 1642 . 16575015

상세보기
11 Pachman DR Barton DL Watson JC Loprinzi CL. Chemotherapy-induced peripheral neuropathy: prevention and treatment . Clin Pharmacol Ther . 2011 ; 90 : 377 - 387 . 21814197

상세보기
12 Verstappen CCP Heimans JJ Hoekman K Postma TJ Neurotoxic complications of chemotherapy in patients with cancer: clinical signs and optimal management . Drugs . 2003 ; 63 : 1549 - 1563 . 12887262
13 Hershman DL Lacchetti C Dworkin RH , et al Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology Clinical Practice Guideline . J Clin Oncol . 2014 ; 32 : 1941 - 1967 . 24733808

상세보기
14 Schroeder S Meyer-Hamme G Epplee S. Acupuncture for chemotherapy-induced peripheral neuropathy (CIPN): a pilot study using neurography . Acupunct Med . 2012 ; 30 : 4 - 7 . 22146780

상세보기
15 Ben-Horin I Kahan P Ryvo L Inbar M Lev-Ari S Geva R. Acupuncture and reflexology for chemotherapy-induced peripheral neuropathy in breast cancer . Integr Cancer Ther . 2017 ; 16 : 258 - 262 . 28150504
16 Bao T Seidman AD Piulson L , et al A phase IIA trial of acupuncture to reduce chemotherapy-induced peripheral neuropathy severity during neoadjuvant or adjuvant weekly paclitaxel chemotherapy in breast cancer patients . Eur J Cancer . 2018 ; 101 : 12 - 19 . 30007894

상세보기
17 Park JH Lee J Cho CK Yoo HS. Electroacupuncture for the treatment of the chemotherapy-induced peripheral neuropathy in breast cancer patient: a case report . J Korean Tradit Oncol . 2015 ; 20 : 1 - 9 .
18 Roscoe JA Morrow GR Hickok JT , et al The efficacy of acupressure and acustimulation wrist bands for the relief of chemotherapy-induced nausea and vomiting . J Pain Symptom Manage . 2003 ; 26 : 731 - 742 . 12906958
19 Michael H Nobert K Karl-Heinz C. Handbook of Acupuncture . 1st ed Seoul, South Korea : Hansol Medical ; 2010 .
20 Paice JA Cohen FL. Validity of a verbally administered numeric rating scale to measure cancer pain intensity . Cancer Nurs . 1997 ; 20 : 88 - 93 . 9145556
21 Jensen MP. The validity and reliability of pain measures in adults with cancer . J Pain . 2003 ; 4 : 2 - 21 . 14622723

상세보기
22 Cornblath DR Chaudhry R Carter K , et al Total neuropathy score: validation and reliability study . Neurology . 1999 ; 53 : 1660 - 1664 . 10563609

상세보기
23 Cavaletti G Bogliun G Marzorati L , et al Grading of chemotherapy-induced peripheral neurotoxicity using the Total Neuropathy Scale . Neurology . 2003 ; 61 : 1297 - 1300 . 14610145

상세보기
24 Cavaletti G Frigeni B Lanzani F , et al ; Italian NETox Group . The Total Neuropathy Score as an assessment tool for grading the course of chemotherapy-induced peripheral neurotoxicity: comparison with the National Cancer Institute-Common Toxicity Scale . J Peripher Nerv Syst . 2007 ; 12 : 210 - 215 . 17868248

상세보기
25 Park SB Goldstein D Krishnan AV , et al Chemotherapy-induced peripheral neurotoxicity: a critical analysis . CA Cancer J Clin . 2013 ; 63 : 419 - 437 . 24590861
26 Postma TJ Aaronson NK Heimans JJ , et al The development of an EORTC quality of life questionnaire to assess chemotherapy-induced peripheral neuropathy: the QLQ-CIPN20 . Eur J Cancer . 2005 ; 41 : 1135 - 1139 . 15911236

상세보기
27 Kim HY Kang JH Youn HJ , et al Reliability and validity of the Korean version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire to assess chemotherapy-induced peripheral neuropathy . J Korean Acad Nurs . 2014 ; 44 : 735 - 742 . 25608551

원문보기 상세보기
28 Lavoie Smith EM Barton DL Qin R Steen PD Aaronson NK Loprinzi CL. Assessing patient-reported peripheral neuropathy: the reliability and validity of the European Organization for Research and Treatment of Cancer QLQ-CIPN20 Questionnaire . Qual Life Res . 2013 ; 22 : 2787 - 2799 . 23543373

상세보기
29 Cella DF Tulsky DS Gray G , et al The Functional Assessment of Cancer Therapy scale: development and validation of the general measure . J Clin Oncol . 1993 ; 11 : 570 - 579 . 8445433

상세보기
30 Yoo HJ Ahn SH Eremenco S , et al Korean translation and validation of the Functional Assessment of Cancer Therapy-Breast (FACT-B) scale version 4 . Qual Life Res . 2005 ; 14 : 1627 - 1632 . 16110941

상세보기
31 Ng R Lee CF Wong NS , et al Measurement properties of the English and Chinese versions of the Functional Assessment of Cancer Therapy？Breast (FACT-B) in Asian breast cancer patients . Breast Cancer Res Treat . 2012 ; 131 : 619 - 625 . 21922244

상세보기
32 Brady MJ Cella DF Mo F , et al Reliability and validity of the Functional Assessment of Cancer Therapy？Breast quality-of-life instrument . J Clin Oncol . 1997 ; 15 : 974 - 986 . 9060536

상세보기
33 Park JH Jung IC Lee SH , et al Preliminary study to develop an instrument for pattern identification and evaluation for chemotherapy-induced peripheral neuropathy (CIPN) . J Int Korean Med . 2016 ; 37 : 77 - 89 .
34 Park JH Jung IC Lee SH Lee SH Choi SC Yoo HS. Reliability and validity analysis of an instrument for pattern identification and evaluation in chemotherapy-induced peripheral neuropathy . J Int Korean Med . 2016 ; 37 : 631 - 644 .
35 Jang CE Jung MS Sohn EH , et al The evaluation of changes in peripheral neuropathy and quality-of-life using low-frequency electrostimulation in patients treated with chemotherapy for breast cancer: a study protocol . Trials . 2018 ; 19 : 526 . 30268158

상세보기
36 Coyne PJ Wan W Dodson P Swainey C Smith TJ. A trial of Scrambler therapy in the treatment of cancer pain syndromes and chronic chemotherapy-induced peripheral neuropathy . J Pain Palliat Care Pharmacother . 2013 ; 27 : 359 - 364 . 24143893

상세보기
37 Weisbrod BL Pachman DR Seisler DK , et al Scrambler therapy for treatment of chemotherapy-induced peripheral neuropathy . J Clin Oncol . 2014 ; 32 ( 15 suppl ): 9622 .
38 Pachman DR Linquist BM Barton DL , et al Pilot study of Scrambler therapy for the treatment of chemotherapy-induced peripheral neuropathy . J Clin Oncol . 2012 ; 30 : 9075 .

상세보기
39 Ricci M Pirotti S Scarpi E , et al Managing chronic pain: results from an open-label study using MC5-A Calmare® device . Support Care Cancer . 2012 ; 20 : 405 - 412 . 21394458
40 Cavaletti G Jann S Pace A , et al Multi-center assessment of the Total Neuropathy Score for chemotherapy-induced peripheral neurotoxicity . J Peripher Nerv Syst . 2006 ; 11 : 135 - 141 . 16787511

상세보기
41 National Comprehensive Care Network . Adult cancer pain (Version 2.2019). https://www.nccn.org/professionals/physician_gls/pdf/pain.pdf . https://www.nccn.org/professionals/physician_gls/pdf/pain.pdf . Published 2019. Updated 2019.

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