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[해외논문] Plasmid DNA Nanoparticles for Nonviral Oral Gene Therapy

Nano letters : a journal dedicated to nanoscience and nanotechnology, v.21 no.11, 2021년, pp.4666 - 4675  

Shahriar, S. M. Shatil (Department of Chemical and Biological Engineering , Korea National University of Transportation , Chungju - 27469 , Republic of Korea) ,  An, Jeong Man (Department of Chemical and Biological Engineering , Korea National University of Transportation , Chungju - 27469 , Republic of Korea) ,  Hasan, Mohammad Nazmul (Department of Green BioEngineering , Korea National University of Transportation , Chungju - 27469 , Republic of Korea) ,  Surwase, Sachin S. (Department of Chemical & Biomolecular Engineering , Korea Advanced Institute of Science and Technology (KAIST) , Daejeon - 34141 , Republic of Korea) ,  Kim, Yeu-Chun (Department of Chemical & Biomolecular Engineering , Korea Advanced Institute of Science and Technology (KAIST) , Daejeon - 34141 , Republic of Korea) ,  Lee, Dong Yun (Department of Bioengineering, College of Engineering, and BK21 PLUS Future Biopharmaceutical Human Resources Traini) ,  Cho, Sungpil ,  Lee, Yong-kyu

Abstract AI-Helper 아이콘AI-Helper

Herein, a bile acid-inspired triple padlock oral gene delivery platform is developed, facilitating the protection of the therapeutic gene from gastrointestinal degradation, selective intestinal accumulation through a bile acid-specific transporter, and transportation of pDNA NPs through the enterohe...

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참고문헌 (20)

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