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NTIS 바로가기Nano letters : a journal dedicated to nanoscience and nanotechnology, v.21 no.11, 2021년, pp.4666 - 4675
Shahriar, S. M. Shatil (Department of Chemical and Biological Engineering , Korea National University of Transportation , Chungju - 27469 , Republic of Korea) , An, Jeong Man (Department of Chemical and Biological Engineering , Korea National University of Transportation , Chungju - 27469 , Republic of Korea) , Hasan, Mohammad Nazmul (Department of Green BioEngineering , Korea National University of Transportation , Chungju - 27469 , Republic of Korea) , Surwase, Sachin S. (Department of Chemical & Biomolecular Engineering , Korea Advanced Institute of Science and Technology (KAIST) , Daejeon - 34141 , Republic of Korea) , Kim, Yeu-Chun (Department of Chemical & Biomolecular Engineering , Korea Advanced Institute of Science and Technology (KAIST) , Daejeon - 34141 , Republic of Korea) , Lee, Dong Yun (Department of Bioengineering, College of Engineering, and BK21 PLUS Future Biopharmaceutical Human Resources Traini) , Cho, Sungpil , Lee, Yong-kyu
Herein, a bile acid-inspired triple padlock oral gene delivery platform is developed, facilitating the protection of the therapeutic gene from gastrointestinal degradation, selective intestinal accumulation through a bile acid-specific transporter, and transportation of pDNA NPs through the enterohe...
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