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Anti-Proliferative Effect of Allium senescens L. Extract in Human T-Cell Acute Lymphocytic Leukemia Cells 원문보기

Molecules a journal of synthetic chemistry and natural product chemistry, v.26 no.1, 2021년, pp.35 -   

Kim, Jiyeon (Department of Medical Laboratory Science, College of Health Science, Dankook University, Cheonan 31116, Korea) ,  Lee, Dae Han (yeon@dankook.ac.kr) ,  Badamtsetseg, Bazarragchaa (Department of Pharmacology, School of Medicine, Eulji University, Daejeon 34824, Korea) ,  Lee, Sangwoo (dleogks120@naver.com) ,  Kim, Soon Ae (Department of Environment and Forest Resources, Chungnam National University, Daejeon 34134, Korea)

Abstract AI-Helper 아이콘AI-Helper

Allium species are well known plants distributed throughout the world, and they contain various bioactive components with different biological activities including anti-cancer effects. In this study, we investigated the inhibitory effect of Allium senescens L. (A.S.) extract on cell survival and IL-...

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참고문헌 (41)

  1. 1. Parvu M. Toiu A. Vlase L. Alina Parvu E. Determination of some polyphenolic compounds from Allium species by HPLC-UV-MS Nat. Prod. Res. 2010 24 1318 1324 10.1080/14786410903309484 20419559 

  2. 2. Vlase L. Parvu M. Parvu E.A. Toiu A. Chemical constituents of three Allium species from Romania Molecules 2012 18 114 127 10.3390/molecules18010114 23344191 

  3. 3. Moreno-Black G. Folk Medicine: The Art and the Science Steiner R.P. The American Chemical Society Washington, DC, USA 1986 Volume 7 125 137 

  4. 4. Batiha G.E.-S. Beshbishy A.M. Wasef L.G. Elewa Y.H.A. Abdel-Daim M.M. El-Hack M.E.A. Taha A.E. Abd-Elhakim Y.M. Devkota H.P. Chemical Constituents and Pharmacological Activities of Garlic ( Allium sativum L.): A Review Nutrients 2020 12 872 10.3390/nu12030872 32213941 

  5. 5. Kim T.J. Korean Plants V Seoul National University Press Seoul, Korea 1998 

  6. 6. Shin G.-M. Koppula S. Chae Y.-J. Kim H.-S. Lee J.-D. Kim M.-K. Song M. Anti-hepatofibrosis effect of Allium senescens in activated hepatic stellate cells and thioacetamide-induced fibrosis rat model Pharm. Biol. 2018 56 632 642 10.1080/13880209.2018.1529801 31070527 

  7. 7. Noor S.M. Bell R. Ward A.C. Shooting the messenger: Targeting signal transduction pathways in leukemia and related disorders Crit. Rev. Oncol. Hematol. 2011 78 33 44 10.1016/j.critrevonc.2010.05.002 20570172 

  8. 8. Pui C.H. Evans W.E. Acute lymphoblastic leukemia N. Engl. J. Med. 1998 339 605 615 10.1056/NEJM199808273390907 9718381 

  9. 9. Steward-Tharp S.M. Song Y.J. Siegel R.M. O’Shea J.J. New insights into T cell biology and T cell-directed therapy for autoimmunity, inflammation, and immunosuppression Ann. N. Y. Acad. Sci. 2010 1183 123 148 10.1111/j.1749-6632.2009.05124.x 20146712 

  10. 10. Smith-Garvin J.E. Koretzky G.A. Jordan M.S. T cell activation Annu. Rev. Immunol. 2009 27 591 619 10.1146/annurev.immunol.021908.132706 19132916 

  11. 11. Malek T.R. Castro I. Interleukin-2 receptor signaling: At the interface between tolerance and immunity Immunity 2010 33 153 165 10.1016/j.immuni.2010.08.004 20732639 

  12. 12. Dong C. Davis R.J. Flavell R.A. MAP kinases in the immune response Annu. Rev. Immunol. 2002 20 55 72 10.1146/annurev.immunol.20.091301.131133 11861597 

  13. 13. Crabtree G.R. Clipstone N.A. Signal transmission between the plasma membrane and nucleus of T lymphocytes Annu. Rev. Biochem. 1994 63 1045 1083 10.1146/annurev.bi.63.070194.005145 7979236 

  14. 14. Mercurio F. Manning A.M. Multiple signals converging on NF-kappaB Curr. Opin. Cell Biol. 1999 11 226 232 10.1016/S0955-0674(99)80030-1 10209157 

  15. 15. Mori N. Fujii M. Ikeda S. Yamada Y. Tomonaga M. Ballard D.W. Yamamoto N. Constitutive activation of NF-kappaB in primary adult T-cell leukemia cells Blood 1999 93 2360 2368 10090947 

  16. 16. Sahraoui Y. Allouche M. Ammar A. Spanakis E. Clemenceau C. Jasmin C. Perraki M. Varela-Millot C. Georgoulias V. Interleukin 2 production and interleukin 2 receptor expression by human immature leukemic T cells Leukemia 1992 6 1025 1035 1405755 

  17. 17. Jung J.-I. Kim S.Y. Park K.-Y. Sydara K. Lee S.W. Kim S.A. Kim J. In vitro combinatorial anti-proliferative and immunosuppressive effects of Brucea javanica extract with CX-4945 and imatinib in human T-cell acute lymphoblastic leukemia cells Biomed. Pharmacother. 2018 106 403 410 10.1016/j.biopha.2018.06.164 29966986 

  18. 18. Roesslein M. Frick M. Auwärter V. Humar M. Goebel U. Schwer C. Geiger K.K. Pahl H.L. Pannen B.H.J. Loop T. Sevoflurane-Mediated Activation of p38-Mitogen-Activated Stresskinase is Independent of Apoptosis in Jurkat T-Cells Anesthesia Analg. 2008 106 1150 1160 10.1213/ane.0b013e3181683d37 

  19. 19. Sui X. Kong N. Ye L. Han W. Zhou J. Zhang Q. He C. Pan H. p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents Cancer Lett. 2014 344 174 179 10.1016/j.canlet.2013.11.019 24333738 

  20. 20. Suzuki S. Okada M. Shibuya K. Seino M. Sato A. Takeda H. Seino S. Yoshioka T. Kitanaka C. JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells Oncotarget 2015 6 458 470 10.18632/oncotarget.2693 25473894 

  21. 21. Lin A. Dibling B. The true face of JNK activation in apoptosis Aging Cell. 2002 1 112 116 10.1046/j.1474-9728.2002.00014.x 12882340 

  22. 22. Stajner D. Mili N. Canadanovi-Brunet J. Kapor A. Stajner M. Popovi B.M. Exploring Allium species as a source of potential medicinal agents Phytother. Res. 2006 20 581 584 10.1002/ptr.1917 16676298 

  23. 23. Khazaei S. Ramachandran V. Hamid R.A. Esa N.M. Etemad A. Moradipoor S. Patimah I. Flower extract of Allium atroviolaceum triggered apoptosis, activated caspase-3 and down-regulated antiapoptotic Bcl-2 gene in HeLa cancer cell line Biomed. Pharmacother. 2017 89 1216 1226 10.1016/j.biopha.2017.02.082 28320088 

  24. 24. Moutia M. Habti N. Badou A. In Vitro and In Vivo Immunomodulator Activities of Allium sativum L. Evid. Based Complement Alternat. Med. 2018 2018 4984659 10.1155/2018/4984659 30008785 

  25. 25. Isbilen O. Rizaner N. Volkan E. Anti-proliferative and cytotoxic activities of Allium autumnale P. H. Davis (Amaryllidaceae) on human breast cancer cell lines MCF-7 and MDA-MB-231 BMC Complement Altern. Med. 2018 18 30 10.1186/s12906-018-2105-0 29370794 

  26. 26. Bravo L. Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance Nutr. Rev. 1998 56 317 333 10.1111/j.1753-4887.1998.tb01670.x 9838798 

  27. 27. Kendler B.S. Garlic ( Allium sativum ) and onion ( Allium cepa ): A review of their relationship to cardiovascular disease Prev. Med. 1987 16 670 685 10.1016/0091-7435(87)90050-8 3317392 

  28. 28. oli M. Savi M. Garlic Extracts Stimulate Proliferation of Rat Lymphocytes in Vitro by Increasing IL-2 and IL-4 Production Immunopharmacol. Immunotoxicol. 2000 22 163 181 10.3109/08923970009016413 10737264 

  29. 29. Inoue T. Mimaki Y. Sashida Y. Nishino A. Satomi Y. Nishino H. Steroidal glycosides from Allium macleanii and A. senescens , and their inhibitory activity on tumour promoter-induced phospholipid metabolism of HeLa cells Phytochemistry 1995 40 521 525 10.1016/0031-9422(95)00223-T 7546561 

  30. 30. Sena L.A. Chandel N.S. Physiological roles of mitochondrial reactive oxygen species Mol. Cell 2012 48 158 167 10.1016/j.molcel.2012.09.025 23102266 

  31. 31. Zhang J. Wang X. Vikash V. Ye Q. Wu D. Liu Y. Dong W. ROS and ROS-Mediated Cellular Signaling Oxid. Med. Cell Longev. 2016 2016 4350965 10.1155/2016/4350965 26998193 

  32. 32. Yang T. Yao S. Zhang X. Guo Y. Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways Drug Des. Devel. Ther. 2016 10 1389 1397 10.2147/DDDT.S94983 

  33. 33. Okabe S. Tauchi T. Tanaka Y. Sakuta J. Ohyashiki K. Anti-leukemic activity of axitinib against cells harboring the BCR-ABL T315I point mutation J. Hematol. Oncol. 2015 8 97 10.1186/s13045-015-0190-9 26239229 

  34. 34. Stehle F. Schulz K. Fahldieck C. Kalich J. Lichtenfels R. Riemann D. Seliger B. Reduced immunosuppressive properties of axitinib in comparison with other tyrosine kinase inhibitors J. Biol. Chem. 2013 288 16334 16347 10.1074/jbc.M112.437962 23625925 

  35. 35. Eucker J. Zang C. Zhou Y. Li X. Habbel P. Schulz C.O. Scholz C. Liu H. TKI258, a multi-tyrosine kinase inhibitor is efficacious against human infant/childhood lymphoblastic leukemia in vitro Anticancer Res. 2014 34 4899 4907 25202072 

  36. 36. Lopes de Menezes D.E. Peng J. Garrett E.N. Louie S.G. Lee S.H. Wiesmann M. Tang Y. Shephard L. Goldbeck C. Oei Y. CHIR-258: A potent inhibitor of FLT3 kinase in experimental tumor xenograft models of human acute myelogenous leukemia Clin. Cancer Res. 2005 11 5281 5291 10.1158/1078-0432.CCR-05-0358 16033847 

  37. 37. Eucker J. Zang C. Zhou Y. Li X. Habbel P. Neumann C. Scholz C. Liu H. The multi-tyrosine kinase inhibitor TKI258, alone or in combination with RAD001, is effective for treatment of human leukemia with BCR-ABL translocation in vitro Anticancer Res. 2014 34 4909 4914 25202073 

  38. 38. Nguyen A.T. Duez P. Cytotoxic-anticancer drugs from medicinal plants Phytochemistry Research Progress Matsumoto T. Nova Science Publishers, Inc. New York, NY, USA 2008 193 208 

  39. 39. Livak K.J. Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 2001 25 402 408 10.1006/meth.2001.1262 11846609 

  40. 40. Chou T.C. Talalay P. Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors Adv. Enzyme Regul. 1984 22 27 55 10.1016/0065-2571(84)90007-4 6382953 

  41. 41. Zhao L. Wientjes M.G. Au J.L. Evaluation of combination chemotherapy: Integration of nonlinear regression, curve shift, isobologram, and combination index analyses Clin. Cancer Res. 2004 10 7994 8004 10.1158/1078-0432.CCR-04-1087 15585635 

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