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[해외논문] Extracellular Matrix-Based Hydrogels to Tailoring Tumor Organoids

ACS biomaterials science & engineering, v.7 no.9, 2021년, pp.4128 - 4135  

Lee, Hyun Jin (Department of Bio and Brain Engineering , Korea Advanced Institute of Science and Technology , Daejeon 34141 , South Korea) ,  Mun, Siwon (Department of Bio and Brain Engineering , Korea Advanced Institute of Science and Technology , Daejeon 34141 , South Korea) ,  Pham, Duc M. (Department of Bio and Brain Engineering , Korea Advanced Institute of Science and Technology , Daejeon 34141 , South Korea) ,  Kim, Pilnam

Abstract AI-Helper 아이콘AI-Helper

When embedded into a three-dimensional (3D) matrix, cancer stem cells (or cancer-initiating cells) can grow into self-organizing organotypic structures called tumor organoids. During organoid formation, the matrix not only provides structural support but also delivers biochemical signals. Although i...

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