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Molecular Mechanisms Underlying the Biosynthesis of Melatonin and Its Isomer in Mulberry 원문보기

Frontiers in plant science, v.12, 2021년, pp.708752 -   

Zheng, Sha (State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, Southwest University , Chongqing , China) ,  Zhu, Yingxue (State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, Southwest University , Chongqing , China) ,  Liu, Changying (Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Chengdu University , Chengdu , China) ,  Zhang, Shuai (State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, Southwest University , Chongqing , China) ,  Yu, Maode (State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, Southwest University , Chongqing , China) ,  Xiang, Zhonghuai (State Key Laboratory of Silkworm) ,  Fan, Wei ,  Wang, Shuchang ,  Zhao, Aichun

Abstract AI-Helper 아이콘AI-Helper

Mulberry (Morus alba L.) leaves and fruit are traditional Chinese medicinal materials with anti-inflammatory, immune regulatory, antiviral and anti-diabetic properties. Melatonin performs important roles in the regulation of circadian rhythms and immune activities. We detected, identified and quanti...

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참고문헌 (52)

  1. Arnao M. B. Hernandez-Ruiz J. ( 2014 ). Melatonin: plant growth regulator and/or biostimulator during stress? Trends Plant Sci. 19 789 ? 797 . 10.1016/j.tplants.2014.07.006 25156541 

  2. Back K. Tan D. X. Reiter R. J. ( 2016 ). Melatonin biosynthesis in plants: multiple pathways catalyze tryptophan to melatonin in the cytoplasm or chloroplasts. J. Pineal Res. 61 426 ? 437 . 10.1111/jpi.12364 27600803 

  3. Bixiao Z. Xiaodong Z. Pingli H. Lin W. Qiong L. Chao F. ( 2015 ). Overexpression of MzASMT improves melatonin production and enhances drought tolerance in transgenic Arabidopsis thaliana plants. J. Pineal Res. 57 408 ? 417 . 10.1111/jpi.12180 25250844 

  4. Byeon Y. Lee H. J. Lee H. Y. Back K. ( 2016 ). Cloning and functional characterization of the Arabidopsis N-acetylserotonin O-methyltransferase responsible for melatonin synthesis. J. Pineal Res. 60 65 ? 73 . 10.1111/jpi.12289 26484897 

  5. Byeon Y. Lee H. Y. Lee K. Back K. ( 2014 ). Caffeic acid O -methyltransferase is involved in the synthesis of melatonin by methylating N -acetylserotonin in Arabidopsis . J. Pineal Res. 57 219 ? 227 . 10.1111/jpi.12160 25039887 

  6. Chen G. Huo Y. Tan D. X. Liang Z. Zhang W. Zhang Y. ( 2003 ). Melatonin in Chinese medicinal herbs. Life Sci. 73 19 ? 26 . 10.1016/S0024-3205(03)00252-2 12726883 

  7. Diamantini G. Tarzia G. Spadoni G. D’alpaos M. Traldi P. ( 1998 ). Metastable ion studies in the characterization of melatonin isomers. Rapid Commun. Mass Spectrom. 12 1538 ? 1542 . 10.1002/(SICI)1097-0231(19981030)12:20<1538::AID-RCM342>3.0.CO;2-I 

  8. Dollins A. B. Zhdanova I. V. Wurtman R. J. Lynch H. J. Deng M. H. ( 1994 ). Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. Proc. Natl. Acad. Sci. U. S. A. 91 824 ? 1828 . 10.1073/pnas.91.5.1824 8127888 

  9. Feng X. Wang M. Zhao Y. Han P. Dai Y. ( 2014 ). Melatonin from different fruit sources, functional roles, and analytical methods. Trends Food Sci. Technol. 37 21 ? 31 . 10.1016/j.tifs.2014.02.001 

  10. Fernandez-Pachon M. S. Medina S. Herrero-Martin G. Cerrillo I. Berna G. Escudero-Lopez B. ( 2013 ). Alcoholic fermentation induces melatonin synthesis in orange juice. J. Pineal Res. 56 31 ? 38 . 10.1111/jpi.12093 24117835 

  11. Fitzpatrick P. F. ( 1999 ). Tetrahydropterin-dependent amino acid hydroxylases [Review]. Annu. Rev. Biochem. 68 355 ? 381 . 10.1146/annurev.biochem.68.1.355 10872454 

  12. Garcia-Parrilla M. C. Cantos E. Troncoso A. M. ( 2009 ). Analysis of melatonin in foods. J. Food Compost. Anal. 22 177 ? 183 . 10.1016/j.jfca.2008.09.009 

  13. Gardana C. Iriti M. Stuknyt M. De Noni I. Simonetti P. ( 2014 ). Melatonin isomer’ in wine is not an isomer of the melatonin but tryptophan-ethylester. J. Pineal Res. 57 435 ? 441 . 10.1111/jpi.12183 25251161 

  14. Gomez F. J. Hernandez I. G. Martinez L. D. Silva M. F. Cerutti S. ( 2013 ). Analytical tools for elucidating the biological role of melatonin in plants by LC-MS/MS. Electrophoresis 34 1749 ? 1756 . 10.1002/elps.201200569 23686585 

  15. Gomez F. J. Raba J. Cerutti S. Silva M. F. ( 2012 ). Monitoring melatonin and its isomer in Vitis vinifera cv. Malbec by UHPLC-MS/MS from grape to bottle. J. Pineal Res. 52 349 ? 355 . 10.1111/j.1600-079X.2011.00949.x 22225625 

  16. Hattori A. Migitaka H. Iigo M. Itoh M. Reiter R. J. ( 1995 ). Identification of melatonin in plants and its effects on plasma melatonin levels and binding to melatonin receptors in vertebrates. Biochem. Mol. Biol. Int. 35 627 ? 634 . 7773197 

  17. He N. Zhang C. Qi X. Zhao S. Tao Y. Yang G. ( 2013 ). Draft genome sequence of the mulberry tree Morus notabilis . Nat. Commun. 4 : 2445 . 10.1038/ncomms3445 24048436 

  18. Huang Y. H. Liu S. J. Yuan S. Guan C. Tian D. Y. Cui X. ( 2017 ). Overexpression of ovine AANAT and HIOMT genes in switchgrass leads to improved growth performance and salt-tolerance. Sci. Rep. 7 : 12212 . 10.1038/s41598-017-12566-2 28939842 

  19. Iriti M. Rossoni M. Faoro F. ( 2006 ). Melatonin content in grape: myth or panacea? J. Sci. Food Agric. 86 1432 ? 1438 . 10.1002/jsfa.2537 

  20. Iriti M. Vigentini I. ( 2015 ). Tryptophan-ethylester, the false (unveiled) melatonin isomer in red wine. Int. J. Tryptophan Res. 8 27 ? 29 . 10.4137/IJTR.S22450 25922582 

  21. Jiao F. Luo R. Dai X. Liu H. Yu G. Han S. ( 2020 ). Chromosome-Level Reference Genome and Population Genomic Analysis Provide Insights into the Evolution and Improvement of Domesticated Mulberry ( Morus alba ). Mol. Plant 13 1001 ? 1012 . 10.1016/j.molp.2020.05.005 32422187 

  22. Kang K. Kong K. Park S. Natsagdorj U. Kim Y. S. Back K. ( 2011 ). Molecular cloning of a plant N-acetylserotonin methyltransferase and its expression characteristics in rice. J. Pineal Res. 50 304 ? 309 . 10.1111/j.1600-079X.2010.00841.x 21210840 

  23. Kang K. Lee K. Park S. Byeon Y. Back K. ( 2013 ). Molecular cloning of rice serotonin N-acetyltransferase, the penultimate gene in plant melatonin biosynthesis. J. Pineal Res. 55 7 ? 13 . 10.1111/jpi.12011 22998587 

  24. Kocadagli T. Yilmaz C. Gokmen V. ( 2014 ). Determination of melatonin and its isomer in foods by liquid chromatography tandem mass spectrometry. Food Chem. 153 151 ? 156 . 10.1016/j.foodchem.2013.12.036 24491714 

  25. Lerner A. B. Case J. D. Takahashi Y. Lee T. H. Mori W. ( 1958 ). Isolation of melatonin, a pineal factor that lightens melanocytes. J. Am. Chem. Soc. 80 : 2587 . 10.1021/ja01543a060 

  26. Lewy A. J. Ahmed S. Jackson J. M. Sack R. L. ( 1992 ). Melatonin shifts human circadian rhythms according to a phase-response curve. Chronobiol. Int. 9 380 ? 392 . 10.3109/07420529209064550 1394610 

  27. Lieberman H. R. Waldhauser F. Garfield G. Lynch H. J. Wurtman R. J. ( 1984 ). Effects of melatonin on human mood and performance. Brain Res. 323 201 ? 207 . 10.1016/0006-8993(84)90290-7 6525511 

  28. Liu C. Zhao A. Zhu P. Li J. Han L. Wang X. ( 2015 ). Characterization and Expression of Genes Involved in the Ethylene Biosynthesis and Signal Transduction during Ripening of Mulberry Fruit. PLoS One 10 : e0122081 . 10.1371/journal.pone.0122081 25822202 

  29. Liu W. Dake Z. Chunfang Z. Chen C. Xin P. Yuan C. ( 2017 ). Genomic Analysis of the ASMT Gene Family in Solanum lycopersicum . Molecules 22 : 1984 . 10.3390/molecules22111984 29144405 

  30. Manchester L. C. Poeggeler B. Alvares F. L. Ogden G. B. Reiter R. J. ( 1995 ). Melatonin immunoreactivity in the photosynthetic prokaryote Rhodospirillum rubrum : implications for an ancient antioxidant system. Cell. Mol. Biol. Res. 41 391 ? 395 . 8867786 

  31. Mukherjee S. David A. Yadav S. Balu?ka F. Bhatla S. C. ( 2014 ). Salt stress-induced seedling growth inhibition coincides with differential distribution of serotonin and melatonin in sunflower seedling roots and cotyledons. Physiol. Plant. 152 714 ? 728 . 10.1111/ppl.12218 24799301 

  32. Pan L. Zheng J. Liu J. Guo J. Liu F. Liu L. ( 2019 ). Analysis of the ASMT Gene Family in Pepper ( Capsicum annuum L.): identification, Phylogeny, and Expression Profiles. Int. J. Genomics 2019 : 7241096 . 10.1155/2019/7241096 31065551 

  33. Poggeler B. Balzer I. Hardeland R. Lerchl A. ( 1991 ). Pineal hormone melatonin oscillates also in the dinoflagellateGonyaulax polyedra. Naturwissenschaften 78 268 ? 269 . 10.1007/BF01134354 

  34. Pothinuch P. Tongchitpakdee S. ( 2011 ). Melatonin contents in mulberry ( Morus spp .) leaves: effects of sample preparation, cultivar, leaf age and tea processing. Food Chem. 128 415 ? 419 . 10.1016/j.foodchem.2011.03.045 25212150 

  35. Reiter R. J. ( 1998 ). Oxidative damage in the central nervous system: protection by melatonin. Prog. Neurobiol. 56 359 ? 384 . 10.1016/S0301-0082(98)00052-5 9770244 

  36. Reiter R. J. Tan D. X. Rosalescorral S. Manchester L. C. ( 2013 ). The universal nature, unequal distribution and antioxidant functions of melatonin and its derivatives. Mini Rev. Med. Chem. 13 373 ? 384 . 10.2174/1389557511313030006 23190034 

  37. Rodrigueznaranjo M. I. Gilizquierdo A. Troncoso A. M. Cantos E. Garciaparrilla M. C. ( 2011 ). Melatonin: a new bioactive compound in wine. J. Food Compost. Anal. 24 603 ? 608 . 10.1016/j.jfca.2010.12.009 

  38. Sanchez-Salcedo E. M. Mena P. Garcia-Viguera C. Martinez J. J. Hernandez F. ( 2015 ). Phytochemical evaluation of white ( Morus alba L.) and black ( Morus nigra L.) mulberry fruits, a starting point for the assessment of their beneficial properties. J. Funct. Foods 12 399 ? 408 . 10.1016/j.jff.2014.12.010 

  39. Sangkyu P. Yeong B. Kyoungwhan B. ( 2013 ). Functional analyses of three ASMT gene family members in rice plants. J. Pineal Res. 55 409 ? 415 . 10.1111/jpi.12088 24033370 

  40. Spadoni G. Balsamini C. Diamantini G. Tontini A. Tarzia G. Mor M. ( 2001 ). 2-N-acylaminoalkylindoles: design and quantitative structure-activity relationship studies leading to MT2-selective melatonin antagonists. J. Med. Chem. 44 2900 ? 2912 . 10.1021/jm001125h 11520198 

  41. Sprenger J. Hardeland R. Fuhrberg B. Han S. Z. ( 1999 ). Melatonin and Other 5-Methoxylated Indoles in Yeast : presence in High Concentrations and Dependence on Tryptophan Availability. Cytologia 64 209 ? 213 . 10.1508/cytologia.64.209 

  42. Stasica P. Ulanski P. Rosiak J. M. ( 1998 ). Melatonin as a hydroxyl radical scavenger. J. Pineal Res. 25 65 ? 6 . 10.1111/j.1600-079X.1998.tb00387.x 9694406 

  43. Tan D. X. Hardeland R. Manchester L. C. Rosales-Corral S. Coto-Montes A. Boga J. A. ( 2012 ). Emergence of naturally occurring melatonin isomers and their proposed nomenclature. J. Pineal Res. 53 113 ? 121 . 10.1111/j.1600-079X.2012.00979.x 22332602 

  44. Tan D. X. Reiter R. J. ( 2020 ). An evolutionary view of melatonin synthesis and metabolism related to its biological functions in plants. J. Exp. Bot. 71 4677 ? 4689 . 10.1093/jxb/eraa235 32413108 

  45. Tarzia G. Diamantini G. Digiacomo B. Spadoni G. Esposti D. Nonno R. ( 1997 ). 1-(2-alkanamidoethyl)-6-methoxyindole derivatives: a new class of potent indole melatonin analogues. J. Med. Chem. 40 2003 ? 2010 . 10.1021/jm960653j 9207941 

  46. Tarzia G. Diamantini G. Spadoni G. ( 1999 ). Indole Melatonin Agonists and Antagonists Derived by Shifting the Melatonin Side Chain from the C-3 to the N-1 or to the C-2 Indole Position. Biol. Signals Recept. 8 24 ? 31 . 10.1159/000014565 10085459 

  47. Vitalini S. Dei Cas M. Rubino F. M. Vigentini I. Foschino R. Iriti M. ( 2020 ). LC-MS/MS-Based Profiling of Tryptophan-Related Metabolites in Healthy Plant Foods. Molecules 25 : 311 . 10.3390/molecules25020311 31940983 

  48. Vitalini S. Gardana C. Simonetti P. Fico G. Iriti M. ( 2013 ). Melatonin, melatonin isomers and stilbenes in Italian traditional grape products and their antiradical capacity. J. Pineal Res. 54 322 ? 333 . 10.1111/jpi.12028 23171152 

  49. Wang C. Yin L. Y. Shi X. Y. Xiao H. Kang K. Liu X. Y. ( 2016 ). Effect of Cultivar, Temperature, and Environmental Conditions on the Dynamic Change of Melatonin in Mulberry Fruit Development and Wine Fermentation. J. Food Sci. 81 M958 ? M967 . 10.1111/1750-3841.13263 26953927 

  50. Yeong B. Hyoung Yool L. Kyungjin L. Sangkyu P. Kyoungwhan B. ( 2013 ). Cellular localization and kinetics of the rice melatonin biosynthetic enzymes SNAT and ASMT. J. Pineal Res. 56 107 ? 114 . 10.1111/jpi.12103 24134674 

  51. Zhao Y. Tan D. X. Lei Q. Chen H. Wang L. Li Q. T. ( 2013 ). Melatonin and its potential biological functions in the fruits of sweet cherry. J. Pineal Res. 55 79 ? 88 . 10.1111/jpi.12044 23480341 

  52. Zheng S. Zhu Y. Liu C. Fan W. Xiang Z. Zhao A. ( 2021 ). Genome-wide identification and characterization of genes involved in melatonin biosynthesis in Morus notabilis ( wild mulberry ). Phytochemistry 189 : 112819 . 10.1016/j.phytochem.2021.112819 34087504 

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