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The Journal of investigative dermatology, v.128 no.5, 2008년, pp.1067 - 1070
Elias, Peter M ([1] 1Dermatology Service, Veterans Affairs Medical Center, and Department of Dermatology, University of California, San Francisco, California, USA [2] 2Department of Dermatology, University of California, San Francisco, California, USA) , Steinhoff, Martin ([1] 2Department of Dermatology, University of California, San Francisco, California, USA [2] 3Department of Dermatology, University of Muenster, Muenster, Germany)
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The pathogenesis of atopic dermatitis (AD) has been attributed largely to abnormalities in the adaptive immune system, with key roles played by T-helper 1(Th1)/Th2 cell dysregulation, IgE production, dendritic cell signaling, and mast-cell hyperactivity, resulting in the pruritic, inflammatory d...
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