[논문]Cardiopulmonary Exercise Test Characteristics in Patients with Chronic Obstructive Pulmonary Disease and Associated Pulmonary Hypertension

Holverda, Sebastiaan; Bogaard, Harm J.; Groepenhoff, H.; Postmus, Pieter E.; Boonstra, Anco; Vonk-Noordegraaf, Anton

doi:10.1159/000110207

[해외논문] Cardiopulmonary Exercise Test Characteristics in Patients with Chronic Obstructive Pulmonary Disease and Associated Pulmonary Hypertension

Respiration, v.76 no.2, 2008년, pp.160 - 167

Holverda, Sebastiaan (Department of Pulmonary Diseases and Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands) , Bogaard, Harm J. (Department of Pulmonary Diseases and Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands) , Groepenhoff, H. (Department of Pulmonary Diseases and Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands) , Postmus, Pieter E. (Department of Pulmonary Diseases and Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands) , Boonstra, Anco (Department of Pulmonary Diseases and Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands) , Vonk-Noordegraaf, Anton (Department of Pulmonary Diseases and Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands)

Abstract ▼ AI-Helper

Background: Pulmonary hypertension (PH) is a well-known complication of chronic obstructive pulmonary disease (COPD). It remains unclear whether exercise parameters can be used to discriminate between COPD patients with associated PH (COPD-PH) and COPD patients without associated PH (COPD-nonPH). Objective: To study whether the existence of pulmonary hypertension in COPD is related to characteristic findings in gas exchange and circulatory parameters during cardiopulmonary exercise testing (CPET). Methods: We retrospectively analyzed CPET data in 25 COPD patients in whom right heart catheterization had been performed. Differences were assessed between COPD-PH and COPD-nonPH patients in peak oxygen uptake (VO2 peak), ventilatory efficiency (VE/VCO2), oxygen pulse, maximal ventilation and pulse oximetry (SpO2). Results: PH was found in 10 of 25 patients (mPpa = 33 ± 7 mm Hg), in 15 patients mean pulmonary artery pressure (mPpa) was below 25 mm Hg (18 ± 3 mm Hg). CPET in COPD-PH was characterized by a higher VE/VCO2 at nadir, a higher VE/VCO2 slope, and a lower SpO2 at rest and during exercise, but values in both groups were overlapping considerably. In the whole group mPpa was associated with resting PaO2 (r = -0.70, p < 0.001), VE/VCO2 nadir (r = 0.43, p < 0.05), and inversely related to SpO2 at rest and during exercise (r = -0.58 and r = -0.64, p < 0.01, respectively). Conclusion: Although CPET characteristics showed a large overlap in both groups, the existence of PH in COPD is associated with a significantly reduced ventilatory efficiency during CPET. However, a low SpO2 at rest and a further decrease during exercise similarly suggest the presence of PH in COPD.Copyright © 2007 S. Karger AG, Basel

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10.1056%2FNEJM197204272861703
10.1159%2F000195950
10.1164%2Frccm.2107027
10.1378%2Fchest.127.5.1531
10.1136%2Fthx.2005.042994
10.1183%2F09031936.04.00118303
10.1136%2Fthx.36.10.752
10.1136%2Fthorax.57.12.1050
10.1183%2F09031936.03.00115402
10.1161%2Fhc2901.093198
10.1016%2Fj.jacc.2004.02.032
10.1183%2F09031936.05.00034805
10.1183%2F09031936.05.00034905
10.1183%2F09031936.05.00035005
10.1164%2Frccm.2202033
10.1378%2Fchest.94.5.931
10.1159%2F000196647
10.1378%2Fchest.102.4.1028
10.1016%2Fj.jacc.2006.01.048
10.1378%2Fchest.83.3.446
10.1186%2Fcc1049
10.1378%2Fchest.97.2.268
10.1161%2F01.CIR.0000091409.53101.E8
10.1164%2Frccm.200401-006OC

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[해외논문] Cardiopulmonary Exercise Test Characteristics in Patients with Chronic Obstructive Pulmonary Disease and Associated Pulmonary Hypertension

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[해외논문] Cardiopulmonary Exercise Test Characteristics in Patients with Chronic Obstructive Pulmonary Disease and Associated Pulmonary Hypertension

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