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Abstract ▼ AI-Helper

Background Osteoporosis is a musculoskeletal disease characterized by decrease of bone strength and become more and more prevalent in Korea. Body weight is positively related with bone mineral density but relationship between waist circumference which reflects the amount of visceral fat and bone min...

Background Osteoporosis is a musculoskeletal disease characterized by decrease of bone strength and become more and more prevalent in Korea. Body weight is positively related with bone mineral density but relationship between waist circumference which reflects the amount of visceral fat and bone mineral density remains unclear. Methods We performed cross sectional study on healthy menopausal women who took annual health exam at the Seoul National University Hospital Healthcare System Gangnam Center. We excluded those who have medical disease or take medication that can affect bone mineral density(BMD), and finally analysed the data of 957 healthy postmenopausal women. We considered alcohol and exercise as lifestyle factors affecting BMD. We calculated odds ratio of abdominal obesity over BMD according to body mass index(BMI). Results When adjusted for age, height, weight, drinking and exercise, The odds ratio of having abnormal BMD was 2.51(95% CI 1.48-4.24) for lumbar vertebrae and 1.35(95% CI 0.77-2.49) for hip bone among women with abdominal obesity in normal or underweight group(BMI<23 kg/m2). Also there was tendency of increasing odds ratio with decreasing BMI. Conclusions There seems to be increased risk of having abnormal lumbar BMD among postmenopausal women with abdominal obesity in normal or underweight group(BMI<23 kg/m2). Following study on the mechanism of this observation is necessary.

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