본 연구는 시멘트 지면에서 10km 달리기 전과 후 VAS(visual analogue pain rating scales)와 근골격계 손상과 관련한 혈중 표식인자(CPK; creatine phosphokinase, LDH; latate dehydrogenase, COMP; cartilage oligomeric matrix protein) 발현의 변화 차이를 규명하기 위하여 실시되었다. 이를 위해 20명의 마라토너가 자원하였으며, 청년집단 (YG, 24.60${\pm}$3.13yrs)과 중년 집단(MG, 44.30${\pm}$2.83yrs) 각각 10명씩 참가하였다. 실험을 위한 목표심박수는 최대운동검사를 통해 얻어진 HRmax의 70%로 하였다. CPK와 LDH 분석은 auto-analyzer (ADIVA1650, Bayer, USA)로, COMP는 enzyme-linked immunosorbent assay(AnaMar Medical, Gotenborg, Sweden)로 분석하였다. VAS, CPK 및 LDH는 달리기 후 두 집단 모두에서 유의하게 증가하였으나, 집단간 차이는 없는 것으로 나타났다. 그러나 COMP의 경우 달리기 후에도 유의한 증가가 관찰되었으며, 달리기 후 MG가 YG에 비해 유의하게 증가하였다. 결론적으로 달리기는 일반적으로 근골격계에 손상을 입힐 수 있으나, 골격계의 경우 연령의 증가에 의해서도 영향을 받는 것으로 사료된다.
본 연구는 시멘트 지면에서 10km 달리기 전과 후 VAS(visual analogue pain rating scales)와 근골격계 손상과 관련한 혈중 표식인자(CPK; creatine phosphokinase, LDH; latate dehydrogenase, COMP; cartilage oligomeric matrix protein) 발현의 변화 차이를 규명하기 위하여 실시되었다. 이를 위해 20명의 마라토너가 자원하였으며, 청년집단 (YG, 24.60${\pm}$3.13yrs)과 중년 집단(MG, 44.30${\pm}$2.83yrs) 각각 10명씩 참가하였다. 실험을 위한 목표심박수는 최대운동검사를 통해 얻어진 HRmax의 70%로 하였다. CPK와 LDH 분석은 auto-analyzer (ADIVA1650, Bayer, USA)로, COMP는 enzyme-linked immunosorbent assay(AnaMar Medical, Gotenborg, Sweden)로 분석하였다. VAS, CPK 및 LDH는 달리기 후 두 집단 모두에서 유의하게 증가하였으나, 집단간 차이는 없는 것으로 나타났다. 그러나 COMP의 경우 달리기 후에도 유의한 증가가 관찰되었으며, 달리기 후 MG가 YG에 비해 유의하게 증가하였다. 결론적으로 달리기는 일반적으로 근골격계에 손상을 입힐 수 있으나, 골격계의 경우 연령의 증가에 의해서도 영향을 받는 것으로 사료된다.
The purpose of this study was to clarify the changes of the VAS(visual analogue pain rating scales) and expression of blood biomarkers associated with skeletal-muscular damage(CPK; creatine phosphokinase, LDH; latate dehydrogenase, COMP; cartilage oligomeric matrix protein) at before and after 10km ...
The purpose of this study was to clarify the changes of the VAS(visual analogue pain rating scales) and expression of blood biomarkers associated with skeletal-muscular damage(CPK; creatine phosphokinase, LDH; latate dehydrogenase, COMP; cartilage oligomeric matrix protein) at before and after 10km running on cement road in males. Twenty marathoner participated in this study as subjects and they were composed in two group; i) Young group(YG, 24.60${\pm}$3.13yrs), ii) Middle group(MG, 44.30${\pm}$2.83yrs). The target heart rate(70%) for this study were calculated maximal exercise test. The auto-analyzer(ADIVA1650, Bayer, USA) were used to analyze blood CPK and LDH concentration, and enzyme-linked immunosorbent assay(AnaMar Medical, Gotenborg, Sweden) based on two monoclonal antibody were used to analyze blood COMP concentration. The VAS, blood CPK and LDH concentration were significantly increased after running compared to before in both groups whereas there were no significant differences between groups. The blood COMP concentration were also were significantly increased after running compared to before in both group. The blood COMP concentration after running were significantly higher in MG compared to YG. The results of this study suggest that running may induce skeletal-muscular damage in general but skeletal system can be affected more with ageing.
The purpose of this study was to clarify the changes of the VAS(visual analogue pain rating scales) and expression of blood biomarkers associated with skeletal-muscular damage(CPK; creatine phosphokinase, LDH; latate dehydrogenase, COMP; cartilage oligomeric matrix protein) at before and after 10km running on cement road in males. Twenty marathoner participated in this study as subjects and they were composed in two group; i) Young group(YG, 24.60${\pm}$3.13yrs), ii) Middle group(MG, 44.30${\pm}$2.83yrs). The target heart rate(70%) for this study were calculated maximal exercise test. The auto-analyzer(ADIVA1650, Bayer, USA) were used to analyze blood CPK and LDH concentration, and enzyme-linked immunosorbent assay(AnaMar Medical, Gotenborg, Sweden) based on two monoclonal antibody were used to analyze blood COMP concentration. The VAS, blood CPK and LDH concentration were significantly increased after running compared to before in both groups whereas there were no significant differences between groups. The blood COMP concentration were also were significantly increased after running compared to before in both group. The blood COMP concentration after running were significantly higher in MG compared to YG. The results of this study suggest that running may induce skeletal-muscular damage in general but skeletal system can be affected more with ageing.
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