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Antioxidant and Hepatoprotective Activities of Cirsium setidens NAKAI against CCl4-Induced Liver Damage

The American journal of Chinese medicine, v.36 no.1, 2008년, pp.107 - 114  

Lee, Sung Hyun (School of Biotechnology, Kangwon National University, Chuncheon, Kangwon-do, 200-701, South Korea) ,  Heo, Seong-Il (School of Biotechnology, Kangwon National University, Chuncheon, Kangwon-do, 200-701, South Korea) ,  Li, Lan (School of Veterinary Medicine, Kangwon National University, Chuncheon, Kangwon-do, 200-701, South Korea) ,  Lee, Min Jie (School of Veterinary Medicine, Kangwon National University, Chuncheon, Kangwon-do, 200-701, South Korea) ,  Wang, Myeong-Hyeon (School of Biotechnology, Kangwon National University, Chuncheon, Kangwon-do, 200-701, South Korea)

Abstract AI-Helper 아이콘AI-Helper

The antioxidant activity and hepatoprotective potential of Cirsium setidens Nakai, a widely used medicinal plant, were investigated. The n-butanol (n-BuOH) fraction of leaves and roots of C. setidens had a higher 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity than the other solubl...

참고문헌 (17)

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  2. Castillo, Tirso, Koop, Dennis R., Kamimura, Seiichiro, Triadafilopoulos, George, Tsukamoto, Hidekazu. Role of cytochrome P-450 2E1 in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidation. Hepatology : official journal of the American Association for the Study of Liver Diseases, vol.16, no.4, 992-996.

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  6. Hartley, Dylan P., Kolaja, Kyle L., Reichard, John, Petersen, Dennis R.. 4-Hydroxynonenal and Malondialdehyde Hepatic Protein Adducts in Rats Treated with Carbon Tetrachloride: Immunochemical Detection and Lobular Localization. Toxicology and applied pharmacology, vol.161, no.1, 23-33.

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  10. Marı́, Montserrat, Cederbaum, Arthur I.. CYP2E1 Overexpression in HepG2 Cells Induces Glutathione Synthesis by Transcriptional Activation of γ-Glutamylcysteine Synthetase. The Journal of biological chemistry, vol.275, no.20, 15563-15571.

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  12. Free Radic. Biol. Med. Michiels C. 235 7 

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  14. J. Hepatol. Simibe M. M. 386 34 

  15. Yoshitake, Ikufumi, Ohishi, Eiko, Kubo, Kazuhiro. Hepatoprotective Effects of l-[(2-Thiazolin-2-yl)-amino]acetyl-4-(l,3-dithiol-2-ylidene)-2,3,4,5-tetrahydrolH-l-benzazepin-3,5-dione Hydrochloride (KF-14363) in Various Experimental Liver Injuries. The Japanese journal of pharmacology : official publication of the Japanese Pharmacological Society, vol.57, no.2, 127-136.

  16. Valko, Marian, Leibfritz, Dieter, Moncol, Jan, Cronin, Mark T.D., Mazur, Milan, Telser, Joshua. Free radicals and antioxidants in normal physiological functions and human disease. The international journal of biochemistry & cell biology, vol.39, no.1, 44-84.

  17. YOSHIDA, Takashi, MORI, Kazuko, HATANO, Tsutomu, OKUMURA, Tomoko, UEHARA, Ikue, KOMAGOE, Keiko, FUJITA, Yuzaburo, OKUDA, Takuo. Studies on inhibition mechanism of autoxidation by tannins and flavonoids. V. Radical-scavenging effects of tannins and related polyphenols on 1,1-diphenyl-2-picrylhydrazyl radical.. Chemical & pharmaceutical bulletin, vol.37, no.7, 1919-1921.

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